Lanoconazole

Product Name: Lanoconazole
CAS No.: 101530-10-3
Chemical Name: Lanoconazole
Synonyms: le;Astat;itrile;nnd-318;tjn-318;Lanocozole;latoconazole;LANOCONAZOLE;Lanoconazole USP/EP/BP;[4-(2-chloro-phenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-yl-acetonitrile
CBNumber: CB5333996
Molecular Formula: C14H10ClN3S2
Formula Weight: 319.83
MOL File: 101530-10-3.mol

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Lanoconazole Property

Melting point:: 141.50C
Boiling point:: 477.6±55.0 °C(Predicted)
Density: 1.43±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 3.76±0.10(Predicted)
color: White
CAS DataBase Reference: 101530-10-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
RTECS: NI3393500
Toxicity: LD50 in male, female mice, rats (mg/kg): 3224, 2715, 993, 652 orally; 2158, 1743, 1655, 2596 i.p.; >5000 both species s.c.; LD50 dermally in rats: >5000 mg/kg (Munt)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 32991
Product name: Lanoconazole
Purity: VETRANAL
Packaging: 25mg
Price: $94
Updated: 2024/03/01

TRC

Product number: L174500
Product name: Lanoconazole
Packaging: 100mg
Price: $600
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 11324
Product name: Lanoconazole
Packaging: 10mg
Price: $860
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003122
Product name: LANOCONAZOLE
Purity: 95.00%
Packaging: 100MG
Price: $1593.9
Updated: 2021/12/16

ChemScene

Product number: CS-0003253
Product name: Lanoconazole
Purity: 98.48%
Packaging: 25mg
Price: $160
Updated: 2021/12/16

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Lanoconazole Chemical Properties,Usage,Production

Description

Lanoconazole is a potent antifungal imidazole launched in Japan for the treatment of dermal mycoses. Lanoconazole is reported to be an inhibitor of ergosterol biosynthesis thus altering the ultra structure of the cell wall. It exhibits potent antifungal activity against a wide range of pathogenic fungi including yeast, dermatophytes, dermatiaceous fungi, dimorphic fungi, Aspergihs spp., Penici//ium spp., and Candida spp., being particularly active against Trichophyton spp.. It is considerably more potent than other agents of the same family such as bifonazole and clotrimazole. Clinical efficacy was demonstrated by remarkable improvements in skin symptoms of the patients with tinea pedis, tinea corporis and cruis, candidiasis or tinea versicolor.

Chemical Properties

Light-Yellow Crystals

Originator

Nihon Nohyaku (Japan)

Uses

Antifungal.

Definition

ChEBI: Lanoconazole is a conazole antifungal drug and an imidazole antifungal drug.

brand name

Astat

Lanoconazole Preparation Products And Raw materials

Raw materials

Silica gel N,N-Dimethylformamide Potassium hydroxide Dipotassium rabdosiin Rabdosiin SULFATE STANDARD

Preparation Products

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Lanoconazole Suppliers

Canada 1 China 66 Europe 1 India 4 South Korea 1 Switzerland 1 United Kingdom 5 United States 17 Global 96

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Shanghai Witofly Chemical Co.,Ltd

Tel
Email: sales@witofly.com
Country: China
ProdList: 2864
Advantage: 52

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

Wuhan Dahua Pharmaceutical Co., Ltd.

Tel: 027-59262863 13277907145 3091977954
Fax: 027-59420980
Country: China
ProdList: 4943
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10274
Advantage: 55

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View Lastest Price from Lanoconazole manufacturers

Dideu Industries Group Limited

Product: Lanoconazole 101530-10-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-16

Career Henan Chemical Co

Product: Lanoconazole 101530-10-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 200KG
Release date: 2019-08-30

101530-10-3, LanoconazoleRelated Search:

Tetraphenylcyclopentadienone Miconazole nitrate Phenyl salicylate Iminodiacetonitrile Dimethyl disulfide Itraconazole Selenium sulfide Fluconazole Diphenyl ether Imidazole PHENYL VALERATE Ketoconazole Voriconazole PHENYL RESIN Difluorochloromethane Benzeneacetonitrile Phenylacetic acid acetonitrile

LANOCONAZOLE

[4-(2-chloro-phenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-yl-acetonitrile

(+-)-(e)-(4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene)-1-imidazolylacetonitri

(e)-alpha-(4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene)-1h-imidazole-1-aceton

1h-imidazole-1-acetonitrile,alpha-(4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene)

(E)-alpha-(4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene)-1H-imidazole-1-acetonitrile

1H-Imidazole-1-acetonitrile, alpha-(4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene)-, (E)-(+-)

(E)-2-[4-(2-Chlorophenyl)-1,3-dithiolane-2-ylidene]-2-(1-imidazolyl)acetonitrile

itrile

latoconazole

le

nnd-318

tjn-318

(E)-(+/-)-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile

1H-Imidazole-1-acetonitrile, a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (aE)- (9CI)

1H-Imidazole-1-acetonitrile, a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (E)-

1H-Imidazole-1-acetonitrile, a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (E)-(+-)-

Astat

2-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-yl-acetonitrile

(+-)-(E)-(4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene)-1-imidazolylacetonitrile

Lanocozole

1H-Imidazole-1-acetonitrile, α-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (αE)-

Lanoconazole USP/EP/BP

101530-10-3

C14H10ClN3S2

Intermediates & Fine Chemicals

Pharmaceuticals