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Lanoconazole

Product Name
Lanoconazole
CAS No.
101530-10-3
Chemical Name
Lanoconazole
Synonyms
le;Astat;itrile;nnd-318;tjn-318;Lanocozole;latoconazole;LANOCONAZOLE;Lanoconazole USP/EP/BP;[4-(2-chloro-phenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-yl-acetonitrile
CBNumber
CB5333996
Molecular Formula
C14H10ClN3S2
Formula Weight
319.83
MOL File
101530-10-3.mol
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Lanoconazole Property

Melting point:
141.50C
Boiling point:
477.6±55.0 °C(Predicted)
Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
3.76±0.10(Predicted)
color 
White
CAS DataBase Reference
101530-10-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
RTECS 
NI3393500
Toxicity
LD50 in male, female mice, rats (mg/kg): 3224, 2715, 993, 652 orally; 2158, 1743, 1655, 2596 i.p.; >5000 both species s.c.; LD50 dermally in rats: >5000 mg/kg (Munt)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
32991
Product name
Lanoconazole
Purity
VETRANAL
Packaging
25mg
Price
$94
Updated
2024/03/01
TRC
Product number
L174500
Product name
Lanoconazole
Packaging
100mg
Price
$600
Updated
2021/12/16
AK Scientific
Product number
G613
Product name
Lanoconazole
Packaging
5mg
Price
$49
Updated
2021/12/16
ChemScene
Product number
CS-0003253
Product name
Lanoconazole
Purity
98.48%
Packaging
5mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-0003253
Product name
Lanoconazole
Purity
98.48%
Packaging
10mg
Price
$85
Updated
2021/12/16
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Lanoconazole Chemical Properties,Usage,Production

Description

Lanoconazole is a potent antifungal imidazole launched in Japan for the treatment of dermal mycoses. Lanoconazole is reported to be an inhibitor of ergosterol biosynthesis thus altering the ultra structure of the cell wall. It exhibits potent antifungal activity against a wide range of pathogenic fungi including yeast, dermatophytes, dermatiaceous fungi, dimorphic fungi, Aspergihs spp., Penici//ium spp., and Candida spp., being particularly active against Trichophyton spp.. It is considerably more potent than other agents of the same family such as bifonazole and clotrimazole. Clinical efficacy was demonstrated by remarkable improvements in skin symptoms of the patients with tinea pedis, tinea corporis and cruis, candidiasis or tinea versicolor.

Chemical Properties

Light-Yellow Crystals

Originator

Nihon Nohyaku (Japan)

Uses

Antifungal.

Definition

ChEBI: Lanoconazole is a conazole antifungal drug and an imidazole antifungal drug.

brand name

Astat

Lanoconazole Preparation Products And Raw materials

Raw materials

Silica gel N,N-Dimethylformamide Potassium hydroxide Dipotassium rabdosiin Rabdosiin SULFATE STANDARD

Preparation Products

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Lanoconazole Suppliers

Canada 1 China 66 Europe 1 India 4 South Korea 1 Switzerland 1 United Kingdom 5 United States 17 Global 96
CHEMICAL LAND21
Tel
--
Fax
--
Email
sales21@chemicalland21.com
Country
South Korea
ProdList
6303
Advantage
74
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View Lastest Price from Lanoconazole manufacturers

Dideu Industries Group Limited
Product
Lanoconazole 101530-10-3
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-07-16
Career Henan Chemical Co
Product
Lanoconazole 101530-10-3
Price
US $1.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
200KG
Release date
2019-08-30

101530-10-3, LanoconazoleRelated Search:

Tetraphenylcyclopentadienone Miconazole nitrate Phenyl salicylate Iminodiacetonitrile Dimethyl disulfide Itraconazole Selenium sulfide Fluconazole Diphenyl ether Imidazole PHENYL VALERATE Ketoconazole Voriconazole PHENYL RESIN Difluorochloromethane Benzeneacetonitrile Phenylacetic acid acetonitrile

  • LANOCONAZOLE
  • [4-(2-chloro-phenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-yl-acetonitrile
  • (+-)-(e)-(4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene)-1-imidazolylacetonitri
  • (e)-alpha-(4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene)-1h-imidazole-1-aceton
  • 1h-imidazole-1-acetonitrile,alpha-(4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene)
  • (E)-alpha-(4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene)-1H-imidazole-1-acetonitrile
  • 1H-Imidazole-1-acetonitrile, alpha-(4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene)-, (E)-(+-)
  • (E)-2-[4-(2-Chlorophenyl)-1,3-dithiolane-2-ylidene]-2-(1-imidazolyl)acetonitrile
  • itrile
  • latoconazole
  • le
  • nnd-318
  • tjn-318
  • (E)-(+/-)-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile
  • 1H-Imidazole-1-acetonitrile, a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (aE)- (9CI)
  • 1H-Imidazole-1-acetonitrile, a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (E)-
  • 1H-Imidazole-1-acetonitrile, a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (E)-(+-)-
  • Astat
  • 2-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-yl-acetonitrile
  • (+-)-(E)-(4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene)-1-imidazolylacetonitrile
  • Lanocozole
  • 1H-Imidazole-1-acetonitrile, α-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (αE)-
  • Lanoconazole USP/EP/BP
  • 101530-10-3
  • C14H10ClN3S2
  • Intermediates & Fine Chemicals
  • Pharmaceuticals