Physical properties
ChemicalBook > CAS DataBase List > Tetradecyltrimethylammonium bromide

Tetradecyltrimethylammonium bromide

Physical properties
Product Name
Tetradecyltrimethylammonium bromide
CAS No.
1119-97-7
Chemical Name
Tetradecyltrimethylammonium bromide
Synonyms
TTAB;Tetradecyltrimethylammonium bromide;MTAB;Tetradecyltrimethylammonium bromide;Tetradecyl trimethyl ammonium bromide;Myristyltrimethylammonium bromide;Tetradecanaminium,N,N,N-trimethyl-,bromide;1432;mytab;MitMAB
CBNumber
CB5335152
Molecular Formula
C17H38N.Br
Formula Weight
336.39
MOL File
1119-97-7.mol
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Tetradecyltrimethylammonium bromide Property

Melting point:
245-250 °C(lit.)
Density 
1.1328 (rough estimate)
vapor pressure 
0Pa at 25℃
refractive index 
1.5260 (estimate)
storage temp. 
Store below +30°C.
solubility 
DMF: 2 mg/ml DMSO: 16 mg/ml Ethanol: 33 mg/ml PBS (pH 7.2): 5 mg/ml
form 
Fine Crystalline Powder
color 
White
PH
pH (50g/l, 25℃ : 4.0～6.0
Water Solubility 
H2O:10%(w/v) 20 g/100 mL
λmax
λ: 240 nm Amax: ≤0.08
λ: 250 nm Amax: ≤0.05
λ: 260 nm Amax: ≤0.04
λ: 500 nm Amax: ≤0.02
Sensitive 
Hygroscopic
Merck 
14,6336
BRN 
3633227
Stability:
Stable. Hygroscopic. Incompatible with strong oxidizing agents.
InChIKey
CXRFDZFCGOPDTD-UHFFFAOYSA-M
LogP
2.2 at 20℃
CAS DataBase Reference
1119-97-7(CAS DataBase Reference)
EPA Substance Registry System
Tetradecyl trimethyl ammonium bromide (1119-97-7)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45-27
RIDADR 
UN 3263 8/PG 2
WGK Germany 
3
RTECS 
BS5776000
F 
3
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29239000
Toxicity
LD50 in mice, rats (mg/kg): 12.0, 15.0 i.v. (Issomaa, Bjondahl)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

H373May cause damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.40006
Product name
Tetradecyltrimethylammonium bromide
Purity
forsynthesis
Packaging
25g
Price
$30.8
Updated
2024/03/01
Sigma-Aldrich
Product number
87208
Product name
Myristyltrimethylammonium bromide
Purity
for ion pair chromatography, ≥99.0% (AT)
Packaging
10g
Price
$228
Updated
2024/03/01
Sigma-Aldrich
Product number
8.40006
Product name
Tetradecyltrimethylammonium bromide
Purity
forsynthesis
Packaging
100g
Price
$67.3
Updated
2024/03/01
Sigma-Aldrich
Product number
324411
Product name
Dynamin Inhibitor II, MiTMAB
Packaging
500mg
Price
$85.2
Updated
2024/03/01
TCI Chemical
Product number
T0906
Product name
Tetradecyltrimethylammonium Bromide
Purity
>98.0%(T)
Packaging
25g
Price
$18
Updated
2024/03/01
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Tetradecyltrimethylammonium bromide Chemical Properties,Usage,Production

Physical properties

Cetrimide is a white fine powder crystal with a melting point of 245°C to 250°C. A rough estimate of its density is 1.1328. It is soluble in water with a solubility of 20 g/100 mL.

Description

MiTMAB (1119-97-7) is a dynamin I/II inhibitor targeting the dynamin-phospholipid interaction and inhibiting dynamin GTPase activity with a Ki=940nM.1 Rapidly and reversibly inhibits multiple forms of endocytosis with no acute cellular damage1. A useful pharmacological tool for studying dynamin-mediated trafficking events.2 Induces cytokinesis failure and apoptosis in human cancer cells.3 Induces cytoprotective autophagy in human Jurkat T cells.4

Uses

Disinfectant; deodorant; laboratory reagent.

Uses

Myristyltrimethylammonium has been used in a study to assess a surfactant-controlled synthetic method to obtain a nanophase of mesoporous ceria-zirconia solid solution containing cationic defects in the crystalline structure.??It has also been used in a study to determine the low molecular weight of organic acids in soils and plants by capillary zone electrophoresis.

Definition

Myristyltrimethylammonium bromide is an organic molecular entity.

General Description

Myristyltrimethylammonium bromide is a cationic/zwitterionic type of surfactant.

Purification Methods

Crystallise the bromide from acetone or a mixture of Me2CO and >5% MeOH or Me2CO/EtOH. Wash it with diethyl ether and dry it in a vacuum oven at 60o. It is a cationic detergent. Its solubility is 1g/5g H2O. [Dearden & Wooley J Phys Chem 91 2404 1987, Shelton et al. J Am Chem Soc 68 754 1946, Beilstein 4 III 419, 4 IV 813.]

References

1) ANNIE QUAN. Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II.[J]. Molecular Pharmacology, 2007, 72 6: 1425-1439. DOI:10.1124/mol.107.034207.
2) SAMIR VYAS. Development and validation of a stability indicating method for the enantioselective estimation of omeprazole enantiomers in the enteric-coated formulations by high-performance liquid chromatography.[J]. Journal of Pharmacy and Bioallied Sciences, 2011, 3 2: 310-314. DOI:10.4103/0975-7406.80766.
3) SIMON DE BECO. Endocytosis is required for E-cadherin redistribution at mature adherens junctions.[J]. ACS Catalysis , 2009: 7010-7015. DOI:10.1073/pnas.0811253106.
4) YOON HEE KIM . Inhibition of autophagy enhances dynamin inhibitor-induced apoptosis via promoting Bak activation and mitochondrial damage in human Jurkat T cells[J]. Biochemical and biophysical research communications, 2016, 478 4: Pages 1609-1616. DOI:10.1016/j.bbrc.2016.08.165.

Tetradecyltrimethylammonium bromide Preparation Products And Raw materials

Raw materials

Preparation Products

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Tetradecyltrimethylammonium bromide Suppliers

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View Lastest Price from Tetradecyltrimethylammonium bromide manufacturers

Hebei Longbang Technology Co., Ltd
Product
Tetradecyltrimethylammonium bromide 1119-97-7
Price
US $6.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20TONS
Release date
2024-05-28
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Tetradonium bromide 1119-97-7
Price
US $70.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-05-28
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
alkyltrimethylammoniumbromide 1119-97-7
Price
US $70.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-05-29

1119-97-7, Tetradecyltrimethylammonium bromideRelated Search:

Hexadecyl trimethyl ammonium bromide Octadecy trimethyl ammonium bromide Cetrimide Tetradecyl trimethyl ammonium chloride N-Hexadecyltrimethylammonium chloride Dodecyltrimethylammonium Bromide 1-TETRADECANESULFONIC ACID SODIUM SALT SODIUM TETRADECYL SULFATE Dodecyltrimethylammonium chloride Trimethylstearylammonium Chloride dodecylbis(2-hydroxyethyl)methylammonium chloride Vecuronium bromide TETRAOCTADECYLAMMONIUM BROMIDE Dimethylditetradecylammonium bromide Rocuronium bromide CETYLDIMETHYLETHYLAMMONIUM BROMIDE TETRAHEXADECYLAMMONIUM BROMIDE Ammonium bromide

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  • morpant
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  • Myristyltrimethylammonium bromide Vetec(TM) reagent grade, >=99%
  • Dynamin Inhibitor II, MiTMAB - CAS 1119-97-7 - Calbiochem
  • TTAB
  • TRIMETHYLMYRISTYLAMMONIUM BROMIDE
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  • tetradonium
  • tetradoniumbromide
  • trimethyltetradecyl-ammoniubromide
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  • Myristyltrimethylamm
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  • 1432
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