ChemicalBook > CAS DataBase List > 4-Methylsulphonylacetophenone

4-Methylsulphonylacetophenone

Product Name
4-Methylsulphonylacetophenone
CAS No.
10297-73-1
Chemical Name
4-Methylsulphonylacetophenone
Synonyms
4-(Methyl Sulfonyl);Etoricoxib USP RC A;Etocoxib impurity 1;4'-Mesylacetophenone;4-Methylsulphonylace;Etoricoxib impurity C;Acetophenone Impurity 2;P-METHYLSULFONYLACETOPHENONE;4-METHYLSULFONYLACETOPHENONE;Etoricoxib Related CoMpound A
CBNumber
CB5339796
Molecular Formula
C9H10O3S
Formula Weight
198.24
MOL File
10297-73-1.mol
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4-Methylsulphonylacetophenone Property

Melting point:
126-129 °C(lit.)
Boiling point:
305.56°C (rough estimate)
Density 
1.3339 (rough estimate)
refractive index 
1.5250 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Crystalline Powder or Needles
color 
White to slightly yellow
CAS DataBase Reference
10297-73-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29144000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
549304
Product name
4′-(Methylsulfonyl)acetophenone
Purity
97%
Packaging
25g
Price
$97.8
Updated
2022/05/15
TCI Chemical
Product number
M1678
Product name
4'-(Methylsulfonyl)acetophenone
Purity
>98.0%(GC)
Packaging
25g
Price
$84
Updated
2024/03/01
TCI Chemical
Product number
M1678
Product name
4'-(Methylsulfonyl)acetophenone
Purity
>98.0%(GC)
Packaging
250g
Price
$522
Updated
2024/03/01
Alfa Aesar
Product number
H54072
Product name
4'-(Methylsulfonyl)acetophenone, 97+%
Packaging
1g
Price
$28.65
Updated
2024/03/01
Alfa Aesar
Product number
H54072
Product name
4'-(Methylsulfonyl)acetophenone, 97+%
Packaging
5g
Price
$89.65
Updated
2024/03/01
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4-Methylsulphonylacetophenone Chemical Properties,Usage,Production

Chemical Properties

white to slightly yellow cryst. powder or needles

Uses

4-(Methylsulfonyl)acetophenone is an impurity of Etoricoxib (E934100), which is a specific inhibitor of COX-2.

Uses

4′-(Methylsulfonyl)acetophenone may be used in the synthesis of:

  • 3-(4-Methylsulfonylphenyl)-4-phenyl-2(5H)-furanone with potent apoptosis-inducing ability.
  • Bromo-4-methylsulfonylacetophenone, an intermediate for preparing DL-threo-2-dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol.
  • 1-N-Substituted-3,5-diphenyl-2-pyrazoline derivatives, which show promising anti-inflammatory activity.

4-Methylsulphonylacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Methylsulphonylacetophenone Suppliers

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View Lastest Price from 4-Methylsulphonylacetophenone manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
4-Methylsulphonylacetophenone 10297-73-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-10
Hebei Zhanyao Biotechnology Co. Ltd
Product
4'-Methylsulphonyl Acetophenone 10297-73-1
Price
US $10.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2021-10-29
Career Henan Chemical Co
Product
4-Methylsulphonylacetophenone 10297-73-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2018-08-20

10297-73-1, 4-MethylsulphonylacetophenoneRelated Search:

4'-Methylacetophenone Dichloroacetonitrile Diphenyl ether 4-Nitroacetophenone 4'-Chloroacetophenone 4-Methylsulphonyl benzaldehyde 4'-Methoxyacetophenone 4'-Hydroxyacetophenone 3-Nitroacetophenone Phenyl salicylate 3-Methoxyacetophenone PHENYL VALERATE PIPERACETAZINE (250 MG) Etoricoxib Impurity 9 2-CHLORO-1,3-DIMETHYLAMINO TRIMETHINIUM HEXAFLUOROPHOSPHATE PHENYL RESIN Etoricoxib Etoricoxib Impurity 15

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