Bendamustine
- Product Name
- Bendamustine
- CAS No.
- 16506-27-7
- Chemical Name
- Bendamustine
- Synonyms
- 4-(5-(bis(2-chloroethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoic acid;Bendamustine;4-(5-(Bis(2-chloroethyl);-1-methyl-1H-benzo[d]imidazol-2-yl);5-(Bis(2-chloroethyl)amino)-1-methyl-2-benzimidazolebutyric acid;5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid;1H-BenziMidazole-2-butanoicacid, 5-[bis(2-chloroethyl)aMino]-1-Methyl-;4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid;alkylating,SDX-105,inhibit,DNA Alkylator/Crosslinker,antimetabolite,purine,anticancer,Apoptosis,Bendamustine,SDX 105,Inhibitor,DNA;BendamustineQ: What is Bendamustine Q: What is the CAS Number of Bendamustine Q: What is the storage condition of Bendamustine Q: What are the applications of Bendamustine
- CBNumber
- CB5340488
- Molecular Formula
- C16H21Cl2N3O2
- Formula Weight
- 358.26
- MOL File
- 16506-27-7.mol
Bendamustine Property
- Boiling point:
- 585.2±50.0 °C(Predicted)
- Density
- 1.31±0.1 g/cm3(Predicted)
- storage temp.
- -20°C, protect from light
- solubility
- DMSO : 100 mg/mL (279.13 mM; Need ultrasonic)
- pka
- 4.50±0.10(Predicted)
Safety
- Hazardous Substances Data
- 16506-27-7(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H341Suspected of causing genetic defects
H351Suspected of causing cancer
H360May damage fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P281Use personal protective equipment as required.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P308+P313IF exposed or concerned: Get medical advice/attention.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B132558
- Product name
- Bendamustine
- Packaging
- 100mg
- Price
- $290
- Updated
- 2021/12/16
- Product number
- API0005688
- Product name
- BENDAMUSTINE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $409.38
- Updated
- 2021/12/16
- Product number
- API0005688
- Product name
- BENDAMUSTINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1338
- Updated
- 2021/12/16
- Product number
- SC-19231
- Product name
- Bendamustine
- Purity
- 98
- Packaging
- 1g
- Price
- $417
- Updated
- 2021/12/16
- Product number
- CM161908
- Product name
- 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoicacid
- Purity
- 95%
- Packaging
- 1g
- Price
- $833
- Updated
- 2021/12/16
Bendamustine Chemical Properties,Usage,Production
Uses
Treatment of hematologic cancer, especially non-Hodgkin’s lymphoma.
Definition
ChEBI: Bendamustine is a member of benzimidazoles.
brand name
Ribomustine (Amcis AG, Switzerland).
Enzyme inhibitor
This nitrogen mustard and anticancer drug (FWfree-acid = 358.26 g/mol; CAS 16506-27-7), also known by its code name SDX-105, its trade names Treanda?, Treakisym?, Ribomustin?, and Levact?, as well as by its systematic name 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2- yl]butanoic acid, is a relatively nonspecific DNA alkylating agent that causes intra- and inter-strand cross-links. Bendamustine is used in the treatment of chronic lymphocytic leukemia (CLL), Hodgkin’s disease, nonHodgkin’s lymphoma, multiple myeloma and lung cancer. Pharmacokinetics: After intravenous infusion, >95% of the drug becomes protein-bound, mainly to albumin; however, only free bendamustine is active. Bendamustine is metabolized by liver cytochrome p450, and elimination (renal) is biphasic, with an initial half-life of 6–10 minutes and a terminal half-life of approximately 30 minutes.
Bendamustine Preparation Products And Raw materials
Raw materials
Preparation Products
Bendamustine Suppliers
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View Lastest Price from Bendamustine manufacturers
- Product
- Bendamustine 16506-27-7
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2020-01-03