Description
ChemicalBook > CAS DataBase List > 2,6-Diisopropylaniline

2,6-Diisopropylaniline

Description
Product Name
2,6-Diisopropylaniline
CAS No.
24544-04-5
Chemical Name
2,6-Diisopropylaniline
Synonyms
DIPA;2,6-Diisopropylbenzenamine;Amitraz E.C.;Aniline, 2,6-diisopropyl-;2,6-diisopropylphenylamine;2,6-bis(1-methylethyl)-benzenamin;Benzenamine, 2,6-bis(1-methylethyl)-;2,6-diisopropyl-anilin;Diisopropylaniline,90%;2,6-Di-i-propylaniline
CBNumber
CB5349476
Molecular Formula
C12H19N
Formula Weight
177.29
MOL File
24544-04-5.mol
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2,6-Diisopropylaniline Property

Melting point:
-45 °C (lit.)
Boiling point:
257 °C (lit.)
Density 
0.94 g/mL at 25 °C (lit.)
vapor pressure 
<0.01 mm Hg ( 20 °C)
refractive index 
n20/D 1.532(lit.)
Flash point:
255 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
<0.2g/l
form 
Liquid
pka
4.25±0.10(Predicted)
color 
Clear
Water Solubility 
<0.20 g/L
BRN 
2208763
InChIKey
WKBALTUBRZPIPZ-UHFFFAOYSA-N
LogP
3.18 at 20℃
CAS DataBase Reference
24544-04-5(CAS DataBase Reference)
NIST Chemistry Reference
Benzenamine, 2,6-bis(1-methylethyl)-(24544-04-5)
EPA Substance Registry System
2,6-Diisopropylaniline (24544-04-5)
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Safety

Hazard Codes 
Xi
Risk Statements 
52/53-36/37/38
Safety Statements 
61-37/39-26
WGK Germany 
2
RTECS 
BX4025000
TSCA 
Yes
HS Code 
29214980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
157716
Product name
2,6-Diisopropylaniline
Purity
technical grade, 90%
Packaging
100ml
Price
$46.93
Updated
2025/07/31
Sigma-Aldrich
Product number
157716
Product name
2,6-Diisopropylaniline
Purity
technical grade, 90%
Packaging
500ml
Price
$103.55
Updated
2025/07/31
TCI Chemical
Product number
D1755
Product name
2,6-Diisopropylaniline
Purity
>90.0%(GC)
Packaging
25mL
Price
$115
Updated
2025/07/31
TCI Chemical
Product number
D1755
Product name
2,6-Diisopropylaniline
Purity
>90.0%(GC)
Packaging
100mL
Price
$125
Updated
2025/07/31
Sigma-Aldrich
Product number
374733
Product name
2,6-Diisopropylaniline
Purity
97%
Packaging
5g
Price
$81.1
Updated
2025/07/31
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2,6-Diisopropylaniline Chemical Properties,Usage,Production

Description

2,6-Diisopropylaniline is an organic compound with the formula H2NC6H3(CHMe2)2 (Me = CH3). It is a colorless liquid although, like many anilines, samples can appear yellow or brown.

Chemical Properties

Clear liquid

Uses

2,6-Diisopropylaniline acts as an intermediate used in the production of carbodiimides stabilizers, synthetic resins, antioxidants and active pharmaceutical ingredients. It is also used in the preparation of multitopic Schiff-base ligand precursors and 4,5-bis(2,6-diisopropylanilino)-2,7-di-tert-butyl-9,9-dimethylthioxanthene. It also undergoes condensation reaction with triacetylmethane to get -[1-(2,6-diisopropylphenylamino)ethylidene]pentane-2,4-dione. Further, it is used to prepare N-heterocyclic carbene complexes for alfa-arylation of acyclic ketones, amination of haloarenes and aqueous Suzuki coupling. In addition to this, it is used in the prepartion of organocatalyst based on naphthalene diimides.

Uses

2,6-Diisopropylaniline was used in the preparation of multitopic Schiff-base ligand precursors. It was also used in the preparation of NSN-donor proligand, 4,5-bis(2,6-diisopropylanilino)-2,7-di-tert-butyl-9,9-dimethylthioxanthene.

Uses

2,6-Diisopropylaniline is used as intermediate for the manufacture of carbodiimides stabilizers, RIM-PUR, synthetic resins, pesticides, antioxidants, pharmaceuticals and other products.
2,6-Diisopropylaniline may be used in the preparation of multitopic Schiff-base ligand precursors.It may be used in the preparation of NSN-donor proligand, 4,5-bis(2,6-diisopropylanilino)-2,7-di-tert-butyl-9,9-dimethylthioxanthene. It may be used to prepare N-heterocyclic carbene complexes for α-arylation of acyclic ketones, amination of haloarenes, and aqueous Suzuki coupling.
2,6-Diisopropylaniline may be used in the preparation of organocatalyst based on naphthalene diimides (NDIs).

Reactions

2,6-Diisopropylaniline is an amine. It undergoes condensation with triacetylmethane in toluene in the presence of p-toluenesulfonic acid provides 3-[1-(2,6-diisopropylphenylamino)ethylidene]pentane-2,4-dione. 2,6-Diisopropylaniline is an aromatic amine. It reacts with bis(trimethylsilylmethyl)yttrium complexes supported by bulky amidopyridinate (Ap) and amidinate (Amd) ligands to afford yttrium alkyl anilido species. This reaction involves the elimination of TMS (Trimethylsilane).

General Description

2,6-Diisopropylaniline is an aromatic amine. It reacts with bis(trimethylsilylmethyl)yttrium complexes supported by bulky amidopyridinate (Ap) and amidinate (Amd) ligands to afford yttrium alkyl anilido species. This reaction involves the elimination of TMS (Trimethylsilane).

Purification Methods

This method for purifying 2,6-Diisopropylaniline comprises bringing 2,6-diisopropylaniline into contact with an alkyl- or arylsulfonic acid to produce the alkyl- or arylsulfonic acid salt of the 2,6-diisopropylaniline, recrystallizing the sulfonic acid salt in an organic solvent, and subsequently treating the obtained crystals with an alkali.

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2,6-Diisopropylaniline Suppliers

Lonza Group Ltd
Tel
--
Fax
--
Email
info@lonza.com
Country
Switzerland
ProdList
295
Advantage
68
LONZA AG
Tel
--
Fax
--
Email
contact@lonza.com
Country
Switzerland
ProdList
122
Advantage
58
Matrix Fine Chemicals GmbH
Tel
--
Fax
--
Email
nfo@matrix-fine-chemicals.com
Country
Switzerland
ProdList
6968
Advantage
58
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from 2,6-Diisopropylaniline manufacturers

Shandong Vital Biotechnology Co., Ltd.
Product
2,6-Diisopropylaniline 24544-04-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100tons
Release date
2025-11-20
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
2,6-Diisopropylaniline 24544-04-5
Price
US $2.20-8.80/kg
Min. Order
1kg
Purity
99%min
Supply Ability
100kg
Release date
2025-06-12
Hangzhou Verychem Science And Technology Co.Ltd
Product
2,6-Diisopropylaniline 24544-04-5
Price
US $0.00/kg
Min. Order
1000kg
Purity
99%min
Supply Ability
200 tons
Release date
2025-04-27

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