Description References
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Imperatorin

Description References
Product Name
Imperatorin
CAS No.
482-44-0
Chemical Name
Imperatorin
Synonyms
AMMIDIN;Marmelide;MARMELOSIN;Pentosalen;NSC 402949;Imperatori;8-ISOAMYLEN;IMPERATORIN;AKOS 214-72;Enoxypsoralen
CBNumber
CB5355754
Molecular Formula
C16H14O4
Formula Weight
270.28
MOL File
482-44-0.mol
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Imperatorin Property

Melting point:
98-100°C
Boiling point:
333.4°C (rough estimate)
Density 
1.1311 (rough estimate)
refractive index 
1.4350 (estimate)
storage temp. 
-20°C
solubility 
DMSO: ≥5mg/mL
form 
powder
color 
off-white to light brown
λmax
301nm(MeOH)(lit.)
Merck 
14,4925
InChIKey
OLOOJGVNMBJLLR-UHFFFAOYSA-N
LogP
2.983 (est)
CAS DataBase Reference
482-44-0(CAS DataBase Reference)
NIST Chemistry Reference
7H-furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-butenyl)oxy]-(482-44-0)
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Safety

Safety Statements 
24/25
WGK Germany 
3
RTECS 
LV1575000
HS Code 
29419090
Hazardous Substances Data
482-44-0(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
I6659
Product name
Imperatorin
Purity
≥98% (HPLC), powder
Packaging
5mg
Price
$148
Updated
2024/03/01
TCI Chemical
Product number
I0904
Product name
Imperatorin
Purity
>98.0%(HPLC)
Packaging
25mg
Price
$84
Updated
2024/03/01
TCI Chemical
Product number
I0904
Product name
Imperatorin
Purity
>98.0%(HPLC)
Packaging
100mg
Price
$228
Updated
2024/03/01
Cayman Chemical
Product number
26070
Product name
Imperatorin
Purity
≥98%
Packaging
10mg
Price
$74
Updated
2024/03/01
Cayman Chemical
Product number
26070
Product name
Imperatorin
Purity
≥98%
Packaging
25mg
Price
$111
Updated
2024/03/01
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Imperatorin Chemical Properties,Usage,Production

Description

Imperatorin is a kind of furocoumarin and phytochemical that present in citrus fruits. It could be isolated from Urena lobata L. (Malvaceae). It is biosynthesized from Umbelliferae in vivo. It has been found that it has anti-hypertrophic and anti-convulsant effects, and is useful in the HIV-1 research. Previous studies have shown that Imperatorin requires the transcription factor Sp1 to exert its inhibitory effect on the HIV-1. It can further inhibit the expression of cyclin D1 to cause cell cycle arrest at G1 stage. Moreover, it can suppress the HIV-1 replication inside the primary T lymphocytes and transformed cell lines. This inhibitory effect on HIV-1 can also be effectively observed in the HeLa cells. In addition, it has also been shown that it can cause apoptosis of human promyelocytic leukaemia via the cytochrome c/caspase-9 pathway.

References

https://www.scbt.com/scbt/product/imperatorin-482-44-0
https://pubchem.ncbi.nlm.nih.gov/compound/imperatorin#section=Top
https://en.wikipedia.org/wiki/Imperatorin

Chemical Properties

White Solid

Uses

Imperatorin (cas# 482-44-0) is a compound useful in organic synthesis.

Definition

ChEBI: A member of the class of psoralens that is psoralen substituted by a prenyloxy group at position 8. Isolated from Angelica dahurica and Angelica koreana, it acts as a acetylcholinesterase inhibitor.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.

Imperatorin Preparation Products And Raw materials

Raw materials

Preparation Products

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Imperatorin Suppliers

ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4941
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
Aktin Chemicals, Inc.
Tel
86-28-85159085
Fax
86-28-85152372
Email
info@aktinchem.com
Country
China
ProdList
297
Advantage
62
Shenzhen Sungening Bio-Tech Co., Ltd
Tel
+86-0755-89668383
Fax
+86-0755-89594066/4038
Email
sales@sungening.com
Country
China
ProdList
1319
Advantage
65
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4647
Advantage
58
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View Lastest Price from Imperatorin manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Imperatorin 482-44-0
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-10-12
Shanghai Standard Technology Co., Ltd.
Product
Imperatorin 482-44-0
Price
US $0.00/mg
Min. Order
5mg
Purity
Analytical Standard
Supply Ability
10 g
Release date
2019-10-12
NanJing Spring & Autumn Biological Engineering CO., LTD.
Product
Imperatorin 482-44-0 482-44-0
Price
US $15.00/mg
Min. Order
20mg
Purity
≥98%
Supply Ability
1000.00 kgs
Release date
2019-07-09

482-44-0, ImperatorinRelated Search:


  • 2-g)(1)benzopyran-7-one,9-((3-methyl-2-butenyl)oxy)-7h-furo(
  • 6-hydroxy-7-((3-methyl-2-butenyl)oxy)-5-benzofuranacrylicacidelta-lacto
  • 6-hydroxy-7-((3-methyl-2-butenyl)oxy)-5-benzofuranacrylicacidelta-lactone
  • 6-hydroxy-7-(3-methyl-2-butenyloxy)-5-benzofuranacrylicacidomega-lactone
  • 8-isopentenyloxypsoralene
  • 9-((3-methyl-2-butenyl)oxy)-7h-furo(3,2-g)(1)benzopyran-7-one
  • 9-[(3-methyl-2-butenyl)oxy]-7h-furo[3,2-g][1]benzopyran-7-one
  • IMPERATORIN
  • 8-ISOAMYLEN
  • 8-ISOAMYLENOXYPSORALEN
  • AKOS 214-72
  • AMMIDIN
  • MARMELOSIN
  • Enoxypsoralen
  • Pentosalen
  • 8-Isopentenyloxypsoralen
  • 9-(3-Methylbut-2-enyloxy)-7H-furo[3,2-g]chromen-7-one
  • IMPERATORIN WITH HPLC
  • 9-[(3-Methyl-2-butenyl)-oxy]-7H-furo[3,2-γ],[1][benzopyran-7-one
  • 8-isopent-2-enyloxy-6,7-furanocoumarin
  • Marmelide
  • Imperatorin 482-44-0
  • 9-(3-methylbut-2-enoxy)-7-furo[3,2-g][1]benzopyranone
  • AMMidin,8-Isopentenyloxypsoralen
  • MARMELOSIN (IMPERATORIN)
  • Ammidin, Marmelide, Marmelosin, NSC 402949, 9-[(3-Methyl-2-buten-1-yl)oxy]-7h-furo[3,2-g][1]benzopyran-7-one
  • Imperatorin,8-Isopentenyloxypsoralen
  • 9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one
  • MARMELOSIN (IMPERATORIN)(RG)
  • 9-[(3-Methyl-2-buten-1-yl)oxy]-7h-furo[3,2-g][1]benzopyran-7-one
  • NSC 402949
  • Imperatorin, >=98%
  • Ammidin Marmelide Marmelosin NSC 402949
  • Baizhi Extract
  • Imperatorin (Ammidin)
  • Imperatorin CRS
  • Neu5Ac[1Me,4789Ac]α(2-6)Gal[24Bz,3Bn]-β-MPImperatorin
  • 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-buten-1-yl)oxy]-
  • 8-(3-Methyl-2-butenyloxy)psoralen
  • 8-Prenyloxypsoralen
  • 9-[(3-Methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one
  • Imperatorin USP/EP/BP
  • Imperatorin powder, ≥97%
  • Imperatorin powder, ≥98% (HPLC)
  • 9-((3-Methylbut-2-en-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one
  • Imperatori
  • Fluoroestradiol Impurity 34
  • Marmelosin (20 mg)
  • Aegle Marmelos Fruit Dry Extract (175 mg)
  • 482-44-0
  • 482-4-0
  • C16H14O4
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract