ChemicalBook > CAS DataBase List > Ethyl 3-methyl-1H-pyrazole-5-carboxylate

Ethyl 3-methyl-1H-pyrazole-5-carboxylate

Product Name
Ethyl 3-methyl-1H-pyrazole-5-carboxylate
CAS No.
4027-57-0
Chemical Name
Ethyl 3-methyl-1H-pyrazole-5-carboxylate
Synonyms
5-Methyl-1H-pyrazole-3-carboxylic acid ethyl ester;1H-Pyrazole-3-carboxylic acid, 5-methyl-, ethyl ester;AKOS PAO-0427;BUTTPARK 29\06-79;3-Ethoxycarbonyl-5-methylpyrazole;ETHYL 3-METHYLPYRAZOLE-5-CARBOXYLATE;ETHYL 3-METHYL-5-PYRAZOLECARBOXYLATE;Ethyl 5-methylpyrazole-3-carboxylate;Ethyl3-Methylpyrazole-5-carboxylate>5-(Ethoxycarbonyl)-3-methyl-1H-pyrazole
CBNumber
CB5360136
Molecular Formula
C7H10N2O2
Formula Weight
154.17
MOL File
4027-57-0.mol
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Ethyl 3-methyl-1H-pyrazole-5-carboxylate Property

Melting point:
80-84 °C (lit.)
Boiling point:
299.1±20.0 °C(Predicted)
Density 
1.171±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
11.60±0.10(Predicted)
color 
White to Light yellow
BRN 
4192
InChIKey
BOTXQJAHRCGJEG-UHFFFAOYSA-N
CAS DataBase Reference
4027-57-0(CAS DataBase Reference)
NIST Chemistry Reference
3(5)-methyl-5(3)-ethoxycarbonylpyrazole(4027-57-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29331990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
558354
Product name
Ethyl 3-methylpyrazole-5-carboxylate
Purity
98%
Packaging
5g
Price
$70.9
Updated
2024/03/01
TCI Chemical
Product number
E1100
Product name
Ethyl 3-Methylpyrazole-5-carboxylate
Purity
>98.0%(GC)
Packaging
1g
Price
$20
Updated
2024/03/01
TCI Chemical
Product number
E1100
Product name
Ethyl 3-Methylpyrazole-5-carboxylate
Purity
>98.0%(GC)
Packaging
5g
Price
$78
Updated
2024/03/01
Alfa Aesar
Product number
A12304
Product name
Ethyl 3-methyl-1H-pyrazole-5-carboxylate, 97%
Packaging
5g
Price
$126.65
Updated
2024/03/01
Alfa Aesar
Product number
A12304
Product name
Ethyl 3-methyl-1H-pyrazole-5-carboxylate, 97%
Packaging
1g
Price
$39.4
Updated
2021/12/16
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Ethyl 3-methyl-1H-pyrazole-5-carboxylate Chemical Properties,Usage,Production

Chemical Properties

White to yellow solid

Uses

Ethyl 3-Methyl-5-pyrazolecarboxylate is a useful synthetic intermediate. It is used to prepare tetrahydroisoquinoline amide substituted Ph pyrazoles as selective Bcl-2 inhibitors. It is also studies as a hypolipidemic agent.

Uses

Ethyl 3-methylpyrazole-5-carboxylate may be used to synthesize the following ligands:

  • potassium salt of new dihydrobis(3-carboxyethyl-5-methylpyrazolyl)borate (BpCOOEt,Me)
  • [(3-carboxy-5-methyl-1H-1-pyrazolyl) (3-methyl-5-carboxy-1H-1-pyrazolyl)methane, which readily forms Zn(II) and Cd(II) complexes
  • bis(3-carboxy-5-methyl-1H-1-pyrazolyl)methane, which readily forms Zn(II) and Cd(II) complexes

General Description

Ethyl 3-methylpyrazole-5-carboxylate can be prepared by reacting ethyl acetylpyruvate and hydrazine.

Ethyl 3-methyl-1H-pyrazole-5-carboxylate Preparation Products And Raw materials

Raw materials

Hydrazinium hydroxide solution Ethanol Acetone Hydrazine monohydrochloride Diethyl oxalate Sodium

Preparation Products

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Ethyl 3-methyl-1H-pyrazole-5-carboxylate Suppliers

Americas 1 Belgium 1 China 212 Europe 2 France 1 Germany 5 India 14 Japan 2 Russia 1 Switzerland 1 The Netherlands 1 United Kingdom 12 United States 31 Global 284
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View Lastest Price from Ethyl 3-methyl-1H-pyrazole-5-carboxylate manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Ethyl 3-methyl-1H-pyrazole-5-carboxylate 4027-57-0
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2020-04-24
Career Henan Chemical Co
Product
Ethyl 3-methyl-1H-pyrazole-5-carboxylate 4027-57-0
Price
US $2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
customise
Release date
2018-08-09

4027-57-0, Ethyl 3-methyl-1H-pyrazole-5-carboxylateRelated Search:

Methylparaben Bensulfuron methyl Benzocaine Kresoxim-methyl 3-Methylpyrazole Ethyl formate Thiophanate-methyl Pyrazole RESMETHRIN Urethane Methyl acrylate Methyl Parathion-methyl Methyl bromide Ethyl chloroformate ETHYL 1-ETHYL-3-METHYL-1H-PYRAZOLE-5-CARBOXYLATE 5-TERT-BUTYL-2H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER 5-METHYL-1-PHENYL-1H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER

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  • BUTTPARK 29\06-79
  • AKOS PAO-0427
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  • Ethyl 5-methylpyrazole-3-carboxylate
  • 5-Methylpyrazole-3-carboxylic acid ethyl ester
  • 5-Methyl-1H-pyrazol-3-carboxylic acid ethyl ester
  • ethyl 5-methyl-2,3-dihydro-1H-pyrazole-3-carboxylate
  • 4027-57-0
  • Pyrazoles
  • Building Blocks
  • C7 to C8
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Esters
  • Pyrazoles & Triazoles
  • Pyrazole
  • Pyrazoles & Triazoles
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyrazoles
  • Pyrazole series
  • Acids and Derivatives
  • Heterocycles