Prednisone 21-acetate

Product Name: Prednisone 21-acetate
CAS No.: 125-10-0
Chemical Name: Prednisone 21-acetate
Synonyms: Ferr;nisone;Cblconin;d-Corlin;delcortin;deltalone;delta-corlin;PREDNISONE ACETATE;Prendnisone acetate;Prednisone 21-acetat
CBNumber: CB5360752
Molecular Formula: C23H28O6
Formula Weight: 400.46
MOL File: 125-10-0.mol

More

Less

Prednisone 21-acetate Property

Melting point:: 240-242°C (dec.)
alpha: D25 +186° (dioxane)
Boiling point:: 582.0±50.0 °C(Predicted)
Density: 1.28±0.1 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Chloroform (Slightly), Dioxane (Sparingly), DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 12.31±0.60(Predicted)
color: White to Off-White
Water Solubility: 23mg/L(25 ºC)
InChIKey: MOVRKLZUVNCBIP-RFZYENFJSA-N
SMILES: C1(=O)C=C2[C@](C)(C=C1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1=O)(C)[C@@](O)(C(=O)COC(C)=O)CC3)CC2
CAS DataBase Reference: 125-10-0(CAS DataBase Reference)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P314Get medical advice/attention if you feel unwell.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: P2955
Product name: Prednisone Acetate
Packaging: 1G
Price: $96
Updated: 2025/07/31

TCI Chemical

Product number: P2955
Product name: Prednisone Acetate
Packaging: 5G
Price: $288
Updated: 2025/07/31

TRC

Product number: P703825
Product name: Prednisone21-Acetate
Packaging: 1g
Price: $1070
Updated: 2021/12/16

AK Scientific

Product number: J52410
Product name: Prednisoneacetate
Packaging: 1g
Price: $49
Updated: 2021/12/16

ChemScene

Product number: CS-0013902
Product name: Prednisoneacetate
Purity: 99.61%
Packaging: 500mg
Price: $50
Updated: 2021/12/16

More

Less

Prednisone 21-acetate Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Adrenocortical steroid antiinflammatory.

Definition

ChEBI: Cortancyl is a steroid ester, a 20-oxo steroid, an acetate ester, a 17alpha-hydroxy steroid, an 11-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a prednisone.

in vivo

Prednisone acetate (5 mg/kg, Intragastric gavage, once a day for 4 weeks) induces hippocampal LTP impairment by causing neuronal lesions in the dentate gyrus, which reduced glutamic acid (Glu) and NMDAR2A, and impaired spatial memory in Hippocampal LTP impairment model mice^[1].
Prednisone acetate (6 mg/kg, gavage, once a day for 15 days) reduces ocular and peripheral inflammatory responses and restores Th1/Th2 and Th17/Treg immune homeostasis through orchestrating the Notch signaling pathway in Experimental autoimmune uveitis (EAU) rats^[2].

Animal Model:	C57BL/6 mice ^[1]
Dosage:	5 mg/kg
Administration:	Intragastric gavage (i.g.)
Result:	Significantly failed to gain weight. Decreased the population spike (%) after high-frequency stimulation. Reduced the crossing times compared with the control group. Resulted in the impairment of memory, and caused a trend of more serious impairment. Reduced the levels of Glu and gamma-aminobutyric acid (GABA) in the hippocampus. Reduced the expressions of N-methyl-D-aspartate receptors in the hippocampus.

Animal Model:	Experimental autoimmune uveitis ^[2]
Dosage:	6 mg/kg
Administration:	gavage
Result:	Showed fewer manifestations in eyes from day 9 after immunization. Reduced the inflammation in EAU rats. Bound with the pocket of Notch signaling-related molecules with good affinity. Exhibited anti-inflammatory effects through inhibiting Notch signaling activation. Decreased Th1, Th17 and increased Th2, Treg frequencies in EAU.

IC 50

IL-17; IL-10; IL-4

Prednisone 21-acetate Preparation Products And Raw materials

Raw materials

Selenium dioxide Cortisone acetate

Preparation Products

More

Less

Prednisone 21-acetate Suppliers

Canada 1 China 333 Czech 1 Europe 2 Germany 1 India 5 Russia 1 United Kingdom 7 United States 25 Global 376

Toronto Research Chemicals

Tel: --
Fax: --
Email: info@trc-canada.com
Country: Canada
ProdList: 6038
Advantage: 71

More

Less

View Lastest Price from Prednisone 21-acetate manufacturers

Wuhan Haorong Biotechnology Co.,Ltd

Product: Prednisone 21-acetate / Dehydrocortisone acetate 125-10-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500
Release date: 2023-07-31

Henan Suikang Pharmaceutical Co.,Ltd.

Product: Prednisone 21-acetate 125-10-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99.0%
Supply Ability: 1tons
Release date: 2024-04-26

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Prednisone Acetate 125-10-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2024-04-25

125-10-0, Prednisone 21-acetateRelated Search:

Dimethyl disulfide Prednisone Meprednisone Dimethyl sulfate N,N-Dimethylformamide 2-Butoxyethyl acetate Prednisolone Dimethyl phthalate Dimethyl ether Dimethyl carbonate ETHANE Butyl acetate Sodium acetate Isopropyl acetate Dimethyl fumarate Ethylene glycol monoethyl ether acetate 1-Methoxy-2-propyl acetate Glatiramer acetate

17 ALPHA,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE-21-ACETATE

1-DEHYDROCORTISONE ACETATE

1,4-PREGNADIEN-17,21-DIOL-3,11,20-TRIONE 21-ACETATE

1,4-PREGNADIEN-17ALPHA,21-DIOL-3,11,20-TRIONE 21-ACETATE

[2-[(8s,9s,10s,13s,14s,17r)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate

Dehydrocortisone acetate

prednisone 21-acetate

PREDNISONE ACETATE

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione-21-acetate

17α,21-Dihydroxypregna-1,4-diene-3,11,20-trioneacetate

[2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

[2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] ethanoate

acetic acid [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-3,11-diketo-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] ester

Prednisone 21-acetat

1-Cortisone 21-Acetate

21-(Acetyloxy)-17-hydroxy-pregna-1,4-diene-3,11,20-trione

11,20-trione,21-(acetyloxy)-17-hydroxy-pregna-4-diene-3

4-diene-3,11,20-trione,17,21-dihydroxy-pregna-21-acetate

acetic acid [2-(17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl)-2-oxoethyl] ester

Prednisone/ Prednisone Acetate

Prednisone EP Impurity E

delcortin

delta’-dehydrocortisoneacetate

delta-corlin

deltalone

nisone

ACETIC ACID 2-((8S,9S,10R,13S,14S,17R)-17-HYDROXY-10,13-DIMETHYL-3,11-DIOXO-6,7,8,9,10,11,12,13,14,15,16,17-DODECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-17-YL)-2-OXO-ETHYL ESTER

21-Acetoxy-17α-hydroxypregna-1,4-diene-3,11,20-trione

Ferr

Pregna-1,4-diene-3,11,20-trione,21-(acetyloxy)-17-hydroxy-

Cblconin

Prednisone EP Impurity E (Prednisone 21-Acetate)

hot selling Prednisone 21-acetate

Prednisone 21-acetate USP/EP/BP

d-Corlin

Prednisone Impurity 6

Cortancyl (Prednisone 21-acetate)

21-Acetoxy-17a-hydroxypregna-1,4-diene-3,11,20-trione (Prednisone Acetate)

Prednisone 21-acetate / Dehydrocortisone acetate

Prendnisone acetate

Alitretinoin Impurity 22

Prednisolone Impurity 32

Prednisone acetate, Glucocorticoid

Prednisone acetate, 10 mM in DMSO

125-10-0

125-10-2

C23H28O6

40046

Intermediates & Fine Chemicals

Pharmaceuticals

Steroids

125-10-0