3-CHLORO-4-(4-METHYLPIPERAZIN-1-YL)ANILINE

Product Name: 3-CHLORO-4-(4-METHYLPIPERAZIN-1-YL)ANILINE
CAS No.: 16154-72-6
Chemical Name: 3-CHLORO-4-(4-METHYLPIPERAZIN-1-YL)ANILINE
Synonyms: Albb-005529;AKOS B033196;AKOS BB-7856;ASISCHEM Z03257;TIMTEC-BB SBB011555;3-CHLORO-4-(4-METHYLPIPERAZIN-1-YL)ANILINE;3-chloro-4-(4-methyl-1-piperazinyl)aniline;1-(4-AMINO-2-CHLOROPHENYL)-4-METHYLPIPERAZINE;3-chloro-4-(4-methylpiperazin-1-yl)benzenamine;BENZENAMINE, 3-CHLORO-4-(4-METHYL-PIPERAZINYL)
CBNumber: CB5410099
Molecular Formula: C11H16ClN3
Formula Weight: 225.72
MOL File: 16154-72-6.mol

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3-CHLORO-4-(4-METHYLPIPERAZIN-1-YL)ANILINE Property

Melting point:: 141 °C
Boiling point:: 382.1±42.0 °C(Predicted)
Density: 1?+-.0.06 g/cm3(Predicted)
storage temp.: 2-8°C, protect from light
pka: 7.54±0.42(Predicted)
Appearance: Off-white to gray Solid

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC

Product number: C367733
Product name: 3-Chloro-4-(4-methylpiperazin-1-yl)aniline
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA02588
Product name: 1-(4-Amino-2-chlorophenyl)-4-methylpiperazine
Packaging: 500mg
Price: $100
Updated: 2021/12/16

AK Scientific

Product number: N485
Product name: 1-(4-Amino-2-chlorophenyl)-4-methylpiperazine
Packaging: 1g
Price: $126
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA02588
Product name: 1-(4-Amino-2-chlorophenyl)-4-methylpiperazine
Packaging: 1g
Price: $170
Updated: 2021/12/16

Matrix Scientific

Product number: 008154
Product name: 3-Chloro-4-(4-methyl-piperazin-1-yl)-phenylamine
Packaging: 500mg
Price: $208
Updated: 2021/12/16

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3-CHLORO-4-(4-METHYLPIPERAZIN-1-YL)ANILINE Chemical Properties,Usage,Production

Synthesis

16154-62-4

16154-72-6

General procedure for the synthesis of 1-(4-amino-2-chlorophenyl)-4-methylpiperazine from 1-(2-chloro-4-nitrophenyl)-4-methylpiperazine: 1-(2-chloro-4-nitrophenyl)-4-methylpiperazine (13.5 g, 52.8 mmol) was dissolved in methanol (200 mL) and platinum(IV) oxide (0.120 g, 0.528 mmol) was added as catalyst. The reaction system was evacuated and replaced twice with hydrogen, and then the reaction was stirred under hydrogen atmosphere for 48 hours. After completion of the reaction, the crude reaction mixture was filtered through a diatomaceous earth pad and the filter cake was washed with methanol. The filtrate was concentrated to give 1-(4-amino-2-chlorophenyl)-4-methylpiperazine as an orange solid (12 g, 100% yield). The product was characterized by 1H NMR (400 MHz, methanol-d4): δ 2.35 (s, 3H), 2.62 (br.s., 4H), 2.95 (br.s., 4H), 6.63 (dd, J = 8.53, 2.76 Hz, 1H), 6.75-6.81 (m, 1H), 6.90-6.97 (m, 1H); the mass spectra (MS ) showed m/z 226 ([M+H]+).

References

[1] Patent: WO2011/120026, 2011, A1. Location in patent: Page/Page column 35
[2] Patent: WO2016/22460, 2016, A1. Location in patent: Page/Page column 138
[3] Patent: WO2017/66428, 2017, A1. Location in patent: Page/Page column 250

3-CHLORO-4-(4-METHYLPIPERAZIN-1-YL)ANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-CHLORO-4-(4-METHYLPIPERAZIN-1-YL)ANILINE Suppliers

China 56 France 1 Germany 3 India 2 Russia 1 Ukraine 1 United Kingdom 3 United States 12 Global 79

Wuhan Chemwish Technology Co., Ltd

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Shanghai Hanhong Scientific Co.,Ltd.

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Email: info@hanhongsci.com
Country: China
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China Langchem Inc.

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NovoChemy Ltd.

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Shanghai Yolne Chemical Co., Ltd.

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Clearsynth Labs Limited

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HBCChem, Inc.

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Country: United States
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Hangzhou Milestone Pharmtech Co., Ltd.

Tel: 0571-82896630 18969958410
Email: sales_hz@milestonepharmtech.com
Country: China
ProdList: 4894
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View Lastest Price from 3-CHLORO-4-(4-METHYLPIPERAZIN-1-YL)ANILINE manufacturers

Qingdao RENAS Polymer Material Co., Ltd.

Product: 3-chloro-4-(4-methylpiperazin-1-yl)aniline 16154-72-6
Price: US $0.00/kg
Min. Order: 20kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2025-04-14

16154-72-6, 3-CHLORO-4-(4-METHYLPIPERAZIN-1-YL)ANILINERelated Search:

3-chloro-2-(4-methylpiperazin-1-yl)aniline 5-CHLORO-2-(4-METHYLPIPERAZIN-1-YL)ANILINE TIMTEC-BB SBB006244 Methanone, [4-(2-chloro-4-nitrophenyl)-1-piperazinyl](5-methyl-3-phenyl-4-isoxazolyl)- BUTTPARK 83\09-70 3-CHLORO-4-(4-ETHYL-PIPERAZIN-1-YL)-PHENYLAMINE [4-(4-AMINO-2-CHLORO-PHENYL)-PIPERAZIN-1-YL]-(4-PROPOXY-PHENYL)-METHANONE [4-(4-AMINO-2-CHLORO-PHENYL)-PIPERAZIN-1-YL]-O-TOLYL-METHANONE 2-[4-(2-CHLORO-4-NITROPHENYL)PIPERAZIN-1-YL]ETHANOL 3-CHLORO-4-[4-(2-CHLORO-BENZYL)-PIPERAZIN-1-YL]-PHENYLAMINE 1-[4-(4-AMINO-2-CHLORO-PHENYL)-PIPERAZIN-1-YL]-2-METHYL-PROPAN-1-ONE 3-CHLORO-4-(4-METHYLPIPERAZIN-1-YL)ANILINE 3-CHLORO-4-[4-(THIEN-2-YLCARBONYL)PIPERAZIN-1-YL]ANILINE [4-(4-AMINO-2-CHLORO-PHENYL)-PIPERAZIN-1-YL]-PHENYL-METHANONE [4-(4-AMINO-2-CHLORO-PHENYL)-PIPERAZIN-1-YL]-(4-CHLORO-PHENYL)-METHANONE

3-CHLORO-4-(4-METHYLPIPERAZIN-1-YL)ANILINE

3-CHLORO-4-(4-METHYL-PIPERAZIN-1-YL)-PHENYLAMINE

AKOS BB-7856

AKOS B033196

1-(4-AMINO-2-CHLOROPHENYL)-4-METHYLPIPERAZINE

ASISCHEM Z03257

TIMTEC-BB SBB011555

BENZENAMINE, 3-CHLORO-4-(4-METHYL-PIPERAZINYL)

3-chloro-4-(4-methyl-1-piperazinyl)aniline

Albb-005529

3-chloro-4-(4-methylpiperazin-1-yl)benzenamine

3-chloro-4-(4-methyl-1-piperazinyl)aniline trihydrochloride

Benzenamine, 3-chloro-4-(4-methyl-1-piperazinyl)-

3-Chloro-4-(4-methylpiperazin-1-yl)benzenamine - [C28653]

16154-72-6

C11H16ClN3

C11H16N3Cl

Miscellaneous