3-Hydroxyquinoline

Product Name: 3-Hydroxyquinoline
CAS No.: 580-18-7
Chemical Name: 3-Hydroxyquinoline
Synonyms: 3-QUINOLOL;CCRIS 4328;3-Quinolinol;quinolin-3-ol;3-Quinolinol >3-HYDROXYQUINOLINE;3-HYDROXYQUINOLINE 98%;3-Hydroxyquinoline, 95+%;3-HYDROXYQUINOLINE, 97+%;3-Hydroxyquinoline,97%,OR-3952
CBNumber: CB5438970
Molecular Formula: C9H7NO
Formula Weight: 145.16
MOL File: 580-18-7.mol

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3-Hydroxyquinoline Property

Melting point:: 198-202°C
Boiling point:: 264.27°C (rough estimate)
Density: 1.1555 (rough estimate)
refractive index: 1.4500 (estimate)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 4.28(at 20℃)
form: Crystalline Powder
color: Beige
Water Solubility: 587.9mg/L(20 ºC)
InChI: InChI=1S/C9H7NO/c11-8-5-7-3-1-2-4-9(7)10-6-8/h1-6,11H
InChIKey: IQQDNMHUOLMLNJ-UHFFFAOYSA-N
SMILES: N1C2C(=CC=CC=2)C=C(O)C=1

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Safety

Hazard Codes: Xn
Risk Statements: 22
RTECS: VC4050000
HS Code: 29334990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: Q0094
Product name: 3-Quinolinol
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $61
Updated: 2025/07/31

TCI Chemical

Product number: Q0094
Product name: 3-Quinolinol
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $190
Updated: 2025/07/31

TRC

Product number: H953140
Product name: 3-Hydroxyquinoline
Packaging: 5g
Price: $110
Updated: 2021/12/16

Matrix Scientific

Product number: 072900
Product name: 3-Hydroxyquinoline
Purity: 95+%
Packaging: 1g
Price: $14
Updated: 2021/12/16

Matrix Scientific

Product number: 072900
Product name: 3-Hydroxyquinoline
Purity: 95+%
Packaging: 5g
Price: $64
Updated: 2021/12/16

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3-Hydroxyquinoline Chemical Properties,Usage,Production

Chemical Properties

Beige crystalline powder

Uses

3-Hydroxyquinoline is a chemical reagent used in the preparation cyclic peptides with an antitumor functionality. Quinoline derivative as a result of the metabolism by cytochrome P 450.

Synthesis

191162-39-7

580-18-7

General procedure for the synthesis of 3-hydroxyquinoline from quinoline-3-boronic acid: to a round-bottomed flask were added quinoline-3-boronic acid (1.0 mmol), CuSO4-5H2O (0.02 g, 0.1 mmol), CNT-Chit film (10.0 mg), KOH (0.17 g, 3.0 mmol) and deionized water (5.00 mL). The reaction mixture was stirred openly at room temperature for 24 hours. After completion of the reaction, the mixture was filtered and the solids were washed with deionized water. The filtrate was acidified to pH 2-3 with dilute aqueous hydrochloric acid and subsequently extracted with ether (3 x 10 mL). The organic phases were combined and concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography with an eluent ratio of 70% hexane/30% ethyl acetate (v/v) to afford 3-hydroxyquinoline (0.1433 g, 93% yield) as an off-white solid.

References

[1] Tetrahedron Letters, 2018, vol. 59, # 52, p. 4597 - 4601
[2] Journal of the American Chemical Society, 2018, vol. 140, # 13, p. 4623 - 4631
[3] Organic Letters, 2012, vol. 14, # 13, p. 3494 - 3497
[4] Journal of Medicinal Chemistry, 2014, vol. 57, # 6, p. 2536 - 2548
[5] Advanced Synthesis and Catalysis, 2018, vol. 360, # 10, p. 2013 - 2019

3-Hydroxyquinoline Preparation Products And Raw materials

Raw materials

Preparation Products

Solvent Yellow 114

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3-Hydroxyquinoline Suppliers

Austria 1 Belgium 1 Canada 1 China 138 Germany 3 India 9 Japan 1 Switzerland 2 The Netherlands 1 United Kingdom 1 United States 20 Global 178

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Energy Chemical

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Capot Chemical Co., Ltd

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View Lastest Price from 3-Hydroxyquinoline manufacturers

Nanjing jinheyou Trading Co., Ltd.

Product: 3-Hydroxyquinoline 580-18-7
Price: US $0.00/g
Min. Order: 1g
Purity: 98%min
Supply Ability: 20kg/month
Release date: 2019-11-01

Career Henan Chemical Co

Product: 3-Hydroxyquinoline 580-18-7
Price: US $6.00/KG
Min. Order: 2KG
Purity: 98%
Supply Ability: 1KG,50KG,100KG
Release date: 2019-09-03

580-18-7, 3-HydroxyquinolineRelated Search:

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3-HYDROXYQUINOLINE

3-QUINOLOL

quinolin-3-ol

3-HYDROXYQUINOLINE 98%

3-HYDROXYQUINOLINE, 97+%

3-Quinolinol

CCRIS 4328

3-Hydroxyquinoline, 95+%

3-Quinolinol &gt

3-Hydroxyquinoline ISO 9001：2015 REACH

3-Hydroxyquinoline,97%,OR-3952

2,2'-Biquinoline-4,4'-diyl diacetate

580-18-7

Heterocyclic Series