METHYSTICIN
- Product Name
- METHYSTICIN
- CAS No.
- 20697-20-5
- Chemical Name
- METHYSTICIN
- Synonyms
- KAVATIN;KAVAHIN;metysticin;METHYSTICIN;(±)-Methysticin;(±)-Methystici);METHYSTICIN USP/EP/BP;Methysticin (DL-Methysticin;5,6-Dihydro-4-methoxy-6-(3,4-(methylenedioxy)styryl)-2H-pyran-2-one;6-[(E)-2-(1,3-benzodioxol-5-yl)ethenyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one
- CBNumber
- CB5456785
- Molecular Formula
- C15H14O5
- Formula Weight
- 274.27
- MOL File
- 20697-20-5.mol
METHYSTICIN Property
- Melting point:
- 129-131 °C
- Boiling point:
- 496.5±45.0 °C(Predicted)
- Density
- 1.31±0.1 g/cm3(Predicted)
N-Bromosuccinimide Price
- Product number
- VAA69720
- Product name
- DL-Methysticin
- Packaging
- 5mg
- Price
- $900
- Updated
- 2026/06/05
- Product number
- VAA69720
- Product name
- DL-Methysticin
- Packaging
- 2mg
- Price
- $900
- Updated
- 2026/06/05
- Product number
- VAA69720
- Product name
- DL-Methysticin
- Packaging
- 1mg
- Price
- $900
- Updated
- 2026/06/05
- Product number
- VAA69720
- Product name
- DL-Methysticin
- Packaging
- 10mg
- Price
- $900
- Updated
- 2026/06/05
- Product number
- VAA69720
- Product name
- DL-Methysticin
- Packaging
- 0.5mg
- Price
- $900
- Updated
- 2026/06/05
METHYSTICIN Chemical Properties,Usage,Production
Uses
DL-Methysticin is a useful synthetic compound.
in vivo
The kavalactone Methysticin (6 mg/kg) is administered once a week for a period of 6 months to 6 month old transgenic APP/Psen1 mice by oral gavage. Methysticin treatment activates the Nrf2 pathway in the hippocampus and cortex of mice. The Aβ deposition in brains of Methysticin-treated APP/Psen1 mice is not altered compared to untreated mice. However, Methysticin treatment significantly reduces microgliosis, astrogliosis and secretion of the pro-inflammatory cytokines TNF-α and IL-17A. Methysticin treatment results in a significant activation of the Nrf2/ARE pathway in hippocampus and the cortex but not in the midbrain and cerebellum of ARE-luciferase reporter gene mice. Methysticin treatment significantly increases the expression of both genes compared to untreated animals[2].
IC 50
CYP1A1
METHYSTICIN Preparation Products And Raw materials
Raw materials
Preparation Products
METHYSTICIN Suppliers
- Tel
- --
- Fax
- --
- info@yuhaochemical.com
- Country
- China
- ProdList
- 6387
- Advantage
- 52
- Tel
- 021-58955995
- Fax
- 609-228-5909
- sales@medchemexpress.cn
- Country
- United States
- ProdList
- 4861
- Advantage
- 58
- Tel
- 021-51320588
- Fax
- 0086-21-51320502
- tauto@tautobiotech.com
- Country
- China
- ProdList
- 3988
- Advantage
- 66
- Tel
- 021-61119791,13386096464
- Fax
- 021-50190009
- bzswkf@foxmail.com
- Country
- China
- ProdList
- 3921
- Advantage
- 50
- Tel
- +86-21-58589556
- Fax
- +86-21-58589557
- Country
- China
- ProdList
- 413
- Advantage
- 55
- Tel
- 86-021-61559134 15921386130
- Fax
- 021-55068248
- 3423497944@qq.com
- Country
- China
- ProdList
- 8144
- Advantage
- 55
- Tel
- 702-983-3769
- Fax
- 702-983-3769
- sales@albtechnology.com
- Country
- United States
- ProdList
- 2993
- Advantage
- 55
- Tel
- 18607101326 15172504745
- Fax
- +86-27-84254680
- aileen@chemfaces.com
- Country
- China
- ProdList
- 6905
- Advantage
- 55
- Tel
- 888-539-0666
- Fax
- 888-539-0666
- info@emmx.com
- Country
- United States
- ProdList
- 8447
- Advantage
- 60
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 89686
- Advantage
- 60