ChemicalBook > CAS DataBase List > 2-(Dimethylamino)pyridine-5-boronic acid hydrate

2-(Dimethylamino)pyridine-5-boronic acid hydrate

Product Name
2-(Dimethylamino)pyridine-5-boronic acid hydrate
CAS No.
579525-46-5
Chemical Name
2-(Dimethylamino)pyridine-5-boronic acid hydrate
Synonyms
2-DiMethylaMino-5-pyridineboronic acid;2-(Dimethylamino)pyridine-5-boronicacid;5-Borono-2-(dimethylamino)pyridine hydrate;6-(dimethylamino)pyridin-3-yl-3-boronic acid;B-[6-(Dimethylamino)-3-pyridinyl]boronic acid;2-(Dimethylamino)pyridine-5-boronic acid 97%;B-[6-(Dimethylamino)-pyridin-3-yl]boronic acid;6-(DIMETHYLAMINO)PYRIDINE-3-BORONIC ACID HYDRATE;2-(DIMETHYLAMINO)PYRIDINE-5-BORONIC ACID HYDRATE;Boronic acid, B-[6-(dimethylamino)-3-pyridinyl]-
CBNumber
CB5457434
Molecular Formula
C7H11BN2O2
Formula Weight
165.99
MOL File
579525-46-5.mol
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2-(Dimethylamino)pyridine-5-boronic acid hydrate Property

Boiling point:
352.3±52.0 °C(Predicted)
Density 
1.19±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
4.21±0.10(Predicted)
form 
Solid
color 
Yellow
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
D479165
Product name
6-(Dimethylamino)pyridine-3-boronicacid
Packaging
500mg
Price
$150
Updated
2021/12/16
Apolloscientific
Product number
OR2617
Product name
2-(Dimethylamino)pyridine-5-boronicacid
Purity
97%
Packaging
250mg
Price
$70
Updated
2021/12/16
SynQuest Laboratories
Product number
8H60-1-75
Product name
2-(Dimethylamino)pyridine-5-boronic acid
Packaging
250mg
Price
$77
Updated
2021/12/16
AK Scientific
Product number
X0891
Product name
6-(Dimethylamino)pyridine-3-boronicacid
Packaging
250mg
Price
$116
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD09777
Product name
6-(Dimethylamino)pyridin-3-ylboronic acid
Packaging
250mg
Price
$147.5
Updated
2021/12/16
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2-(Dimethylamino)pyridine-5-boronic acid hydrate Chemical Properties,Usage,Production

Uses

2-(Dimethylamino)pyridine-5-boronic acid, hydrade

Synthesis

26163-07-5

73183-34-3

579525-46-5

General procedure for the synthesis of 2-(dimethylamino)pyridine-5-boronic acid from 5-bromo-N,N-dimethylpyridin-2-amine and pinacol ester of bis(boronic acid): to a solution of 1,4-dioxane (20 mL) in 5-bromo-N,N-dimethylpyridin-2-amine (400 mg, 1.989 mmol), was added sequentially 4,4,4',4',5,5,5',5'-octa methyl-2,2'-bis(1,3,2-dioxaborolane) (606 mg, 2.387 mmol), PdCl2(dppf)-CH2Cl2 adduct (162 mg, 0.199 mmol) and potassium acetate (390 mg, 3.98 mmol). The reaction mixture was heated to 100 °C and stirred overnight under nitrogen protection. After completion of the reaction, the mixture was filtered and the filtrate was concentrated under vacuum to afford the crude product (6-(dimethylamino)pyridin-3-yl)boronic acid (420 mg, 0.496 mmol, 25% yield) as a brown oil.LCMS analysis showed the [M+H]+ peak at 167.1.

References

[1] Patent: WO2017/98440, 2017, A1. Location in patent: Page/Page column 170

2-(Dimethylamino)pyridine-5-boronic acid hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(Dimethylamino)pyridine-5-boronic acid hydrate Suppliers

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View Lastest Price from 2-(Dimethylamino)pyridine-5-boronic acid hydrate manufacturers

Dideu Industries Group Limited
Product
2-(Dimethylamino)pyridine-5-boronic acid hydrate 579525-46-5
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-28
Career Henan Chemical Co
Product
2-(Dimethylamino)pyridine-5-boronic acid hydrate 579525-46-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-25

579525-46-5, 2-(Dimethylamino)pyridine-5-boronic acid hydrateRelated Search:


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  • 2-(Dimethylamino)pyridine-5-boronic acid hydrate ISO 9001:2015 REACH
  • B-[6-(Dimethylamino)-3-pyridinyl]boronic acid
  • 6-(dimethylamino)pyridin-3-yl-3-boronic acid
  • 2-(Dimethylamino)pyridine-5-boronic acid hydrate95%
  • B-[6-(Dimethylamino)-pyridin-3-yl]boronic acid
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  • C7H11BN2O2H2O
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  • AMINETERTIARY
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