ChemicalBook > CAS DataBase List > U-74389G

U-74389G

Product Name
U-74389G
CAS No.
153190-29-5
Chemical Name
U-74389G
Synonyms
METHYLATED TIRILAZAD;U-74389G;U74389G,U 74389G;(Z)-2-BUTENEDIONATE;DESMETHYL TIRILAZAD;ABCSSKWSUJMJCP-WQDFMEOSSA-N;21-(4-(2,6 DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE;21-[4-(4,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL]-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE MALEATE;21-[4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]pregna-1,4,9[11]-triene-3,20-dione maleate salt;21-(4-(2,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE (Z)-2-BUTENEDIOATE
CBNumber
CB5461091
Molecular Formula
C41H54N6O6
Formula Weight
726.9
MOL File
153190-29-5.mol
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U-74389G Property

storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
ethanol: soluble20 mg/mL, clear, light yellow
form 
White solid.
color 
White
Sensitive 
Hygroscopic
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
U5882
Product name
U-74389G
Packaging
100mg
Price
$285
Updated
2024/03/01
Alfa Aesar
Product number
J67212
Product name
U-74389G
Purity
98%
Packaging
100mg
Price
$183
Updated
2021/12/16
Cayman Chemical
Product number
75860
Product name
U-74389G
Purity
≥99%
Packaging
50mg
Price
$72
Updated
2024/03/01
Cayman Chemical
Product number
75860
Product name
U-74389G
Purity
≥99%
Packaging
100mg
Price
$115
Updated
2024/03/01
Cayman Chemical
Product number
75860
Product name
U-74389G
Purity
≥99%
Packaging
250mg
Price
$266
Updated
2024/03/01
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U-74389G Chemical Properties,Usage,Production

Description

U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It protects against ischemia-reperfusion injury in animal heart, liver, and kidney models.

Uses

U-74389G is a potent inhibitor of superoxide-mediated lipid peroxidation.

References

1) Braughler et al. (1987) Novel 21-aminosteroids as potent inhibitors of iron-dependent lipid peroxidation; J. Biol. Chem., 262 10438 2) Campo et al. (1996) Protection of ischemic and reperfused rat myocardium by the nonglucocorticoid 21-aminosteroid U-74389G, a new inhibitor of lipid peroxidation; J. Pharmacol. Exp. Ther., 277 333 3) Perna et al. (1996) Protection of rat heart from ischaemia-reperfusion injury by the 21-aminosteroid U-74389G; Pharmacol. Res., 34 25

U-74389G Preparation Products And Raw materials

Raw materials

Preparation Products

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U-74389G Suppliers

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153190-29-5, U-74389GRelated Search:

Amlodipine 1-[4-[(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid N-[4-[[1-[2-(6-METHYL-2-PYRIDINYL)ETHYL]-4-PIPERIDINYL]CARBONYL]PHENYL]METHANESULFONAMIDE DIHYDROCHLORIDE Iron Chelator, Dp44mT U 74389F 2-Pyrimidinamine,4-(1-piperazinyl)-(9CI) 2,4,6-Triaminopyrimidine 4-(PIPERAZIN-1-YL)-2,6-DI-(PYRROLIDIN-1-YL)-PYRIMIDINE U-74389G 1-(1-HEPTYL)-PIPERAZINE 4-AMINO-6-(4-METHYL-1-PIPERAZINYL)PYRIMIDINE 1-N-NONYLPIPERAZINE 1-DECYLPIPERAZINE 1-OCTYLPIPERAZINE

  • U-74389G
  • (Z)-2-BUTENEDIONATE
  • 21-(4-(2,6 DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE
  • 21-(4-(2,6 DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE (Z)-2-BUTENEDIONATE
  • 21-(4-(2,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE (Z)-2-BUTENEDIOATE
  • 21-[4-(4,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL]-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE MALEATE
  • METHYLATED TIRILAZAD
  • DESMETHYL TIRILAZAD
  • 21-[4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]pregna-1,4,9[11]-triene-3,20-dione maleate salt
  • ABCSSKWSUJMJCP-WQDFMEOSSA-N
  • (8S,10S,13S,14S,17S)-17-(2-(4-(2,6-Di(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)acetyl)-10,13-dimethyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one maleate
  • U74389G,U 74389G
  • 153190-29-5
  • C37H50N6O2C4H4O4