U-74389G

Product Name: U-74389G
CAS No.: 153190-29-5
Chemical Name: U-74389G
Synonyms: METHYLATED TIRILAZAD;U-74389G;U74389G,U 74389G;(Z)-2-BUTENEDIONATE;DESMETHYL TIRILAZAD;ABCSSKWSUJMJCP-WQDFMEOSSA-N;21-(4-(2,6 DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE;21-[4-(4,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL]-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE MALEATE;21-[4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]pregna-1,4,9[11]-triene-3,20-dione maleate salt;21-(4-(2,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE (Z)-2-BUTENEDIOATE
CBNumber: CB5461091
Molecular Formula: C41H54N6O6
Formula Weight: 726.9
MOL File: 153190-29-5.mol

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U-74389G Property

storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: ethanol: soluble20 mg/mL, clear, light yellow
form: White solid.
color: White
Sensitive: Hygroscopic
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: U5882
Product name: U-74389G
Packaging: 100mg
Price: $285
Updated: 2024/03/01

Alfa Aesar

Product number: J67212
Product name: U-74389G
Purity: 98%
Packaging: 100mg
Price: $183
Updated: 2021/12/16

Cayman Chemical

Product number: 75860
Product name: U-74389G
Purity: ≥99%
Packaging: 50mg
Price: $72
Updated: 2024/03/01

Cayman Chemical

Product number: 75860
Product name: U-74389G
Purity: ≥99%
Packaging: 100mg
Price: $115
Updated: 2024/03/01

Cayman Chemical

Product number: 75860
Product name: U-74389G
Purity: ≥99%
Packaging: 250mg
Price: $266
Updated: 2024/03/01

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U-74389G Chemical Properties,Usage,Production

Description

U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It protects against ischemia-reperfusion injury in animal heart, liver, and kidney models.

Uses

U-74389G is a potent inhibitor of superoxide-mediated lipid peroxidation.

References

1) Braughler et al. (1987) Novel 21-aminosteroids as potent inhibitors of iron-dependent lipid peroxidation; J. Biol. Chem., 262 10438 2) Campo et al. (1996) Protection of ischemic and reperfused rat myocardium by the nonglucocorticoid 21-aminosteroid U-74389G, a new inhibitor of lipid peroxidation; J. Pharmacol. Exp. Ther., 277 333 3) Perna et al. (1996) Protection of rat heart from ischaemia-reperfusion injury by the 21-aminosteroid U-74389G; Pharmacol. Res., 34 25

U-74389G Preparation Products And Raw materials

Raw materials

Preparation Products

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U-74389G Suppliers

China 49 Switzerland 2 United Kingdom 1 United States 8 Global 60

SIGMA-RBI

Tel: --
Fax: --
Country: Switzerland
ProdList: 6896
Advantage: 91

Alexis Corporation

Tel: --
Fax: --
Email: alexis-ch@alexis-corp.ch
Country: Switzerland
ProdList: 3599
Advantage: 74

153190-29-5, U-74389GRelated Search:

Amlodipine 1-[4-[(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid N-[4-[[1-[2-(6-METHYL-2-PYRIDINYL)ETHYL]-4-PIPERIDINYL]CARBONYL]PHENYL]METHANESULFONAMIDE DIHYDROCHLORIDE Iron Chelator, Dp44mT U 74389F 2-Pyrimidinamine,4-(1-piperazinyl)-(9CI) 2,4,6-Triaminopyrimidine 4-(PIPERAZIN-1-YL)-2,6-DI-(PYRROLIDIN-1-YL)-PYRIMIDINE U-74389G 1-(1-HEPTYL)-PIPERAZINE 4-AMINO-6-(4-METHYL-1-PIPERAZINYL)PYRIMIDINE 1-N-NONYLPIPERAZINE 1-DECYLPIPERAZINE 1-OCTYLPIPERAZINE

U-74389G

(Z)-2-BUTENEDIONATE

21-(4-(2,6 DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE

21-(4-(2,6 DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE (Z)-2-BUTENEDIONATE

21-(4-(2,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL)-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE (Z)-2-BUTENEDIOATE

21-[4-(4,6-DI-1-PYRROLIDINYL-4-PYRIMIDINYL)-1-PIPERAZINYL]-PREGNA-1,4,9(11)-TRIENE-3,20-DIONE MALEATE

METHYLATED TIRILAZAD

DESMETHYL TIRILAZAD

21-[4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]pregna-1,4,9[11]-triene-3,20-dione maleate salt

ABCSSKWSUJMJCP-WQDFMEOSSA-N

(8S,10S,13S,14S,17S)-17-(2-(4-(2,6-Di(pyrrolidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)acetyl)-10,13-dimethyl-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-3-one maleate

U74389G,U 74389G

153190-29-5

C37H50N6O2C4H4O4