1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane

Product Name: 1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane
CAS No.: 1056969-61-9
Chemical Name: 1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane
Synonyms: N3-PEG7-CH2CH2Br;1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane;N3-PEG7-CH2CH2Br/3,6,9,12,15,18,21-Heptaoxatricosane, 1-azido-23-bromo-
CBNumber: CB54657876
Molecular Formula: C16H32BrN3O7
Formula Weight: 458.35
MOL File: 1056969-61-9.mol

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1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane Property

storage temp.: 2-8°C, sealed storage, away from moisture
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS107836
Product name: N3-PEG7-CH2CH2Br
Purity: 97%
Packaging: 250mg
Price: $401
Updated: 2021/12/16

Activate Scientific

Product number: AS107836
Product name: N3-PEG7-CH2CH2Br
Purity: 97%
Packaging: 1g
Price: $869
Updated: 2021/12/16

Acrotein

Product number: B-1434
Product name: N3-PEG7-CH2CH2Br
Purity: 97%
Packaging: 0.5g
Price: $403.33
Updated: 2021/12/16

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1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane Chemical Properties,Usage,Production

Uses

Bromo-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG7-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Biological Activity

Bromo-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane Suppliers

China 20 United States 1 Global 21

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883
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Email: sales@huatengsci.com
Country: China
ProdList: 5873
Advantage: 58

Borenpharm Co., Ltd

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Country: China
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Amatek Scientific Co. Ltd.

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SHANGHAI FDC-CHEMICAL CO.,LTD

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Xi'an Confluore Biological Technology Co., Ltd.

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Beijing Jin Ming Biotechnology Co., Ltd.

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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80514535 19917294565
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View Lastest Price from 1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: N3-PEG7-Br 1056969-61-9
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2026-02-04

Xian confluore Biological Technology Co., Ltd.

Product: Azido-PEG7-Br 1056969-61-9
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

1056969-61-9, 1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosaneRelated Search:

BocNH-PEG7-CH2CH2N3 Azido-PEG7-NHS ester Azide-PEG7-Tos Amino-PEG8-azide Azido-PEG8-acid Azido-PEG7-hydrazide Azido-PEG7-azide Azido-PEG7-COOtBu N3-PEG7-OH

1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane

N3-PEG7-CH2CH2Br

N3-PEG7-CH2CH2Br/3,6,9,12,15,18,21-Heptaoxatricosane, 1-azido-23-bromo-

1056969-61-9