BocNH-PEG7-CH2CH2N3
- Product Name
- BocNH-PEG7-CH2CH2N3
- CAS No.
- 206265-96-5
- Chemical Name
- BocNH-PEG7-CH2CH2N3
- Synonyms
- N3-PEG7-NHBoc;Azido-PEG7-NHBoc;Boc-NH-PEG7-azide;Boc-N-Amido-PEG7-N3;BocNH-PEG7-CH2CH2N3;Azido-PEG7-Boc Amine;1-(Boc-amino)-23-azido-3,6,9,12,15,18,21-heptaoxatricosane;tert-butyl (23-azido-3,6,9,12,15,18,21-heptaoxatricosyl)carbamate;BocNH-PEG7-CH2CH2N3/5,8,11,14,17,20,23-Heptaoxa-2-azapentacosanoic acid, 25-azido-, 1,1-dimethylethyl ester
- CBNumber
- CB83340585
- Molecular Formula
- C21H42N4O9
- Formula Weight
- 494.59
- MOL File
- 206265-96-5.mol
N-Bromosuccinimide Price
- Product number
- BP-23584
- Product name
- t-boc-N-amido-PEG7-azide
- Purity
- 98%
- Packaging
- 100mg
- Price
- $190
- Updated
- 2021/12/16
- Product number
- BP-23584
- Product name
- t-boc-N-amido-PEG7-azide
- Purity
- 98%
- Packaging
- 500mg
- Price
- $390
- Updated
- 2021/12/16
- Product number
- AS104039
- Product name
- BocNH-PEG7-CH2CH2N3
- Purity
- 95+%
- Packaging
- 1g
- Price
- $588
- Updated
- 2021/12/16
- Product number
- BP-23584
- Product name
- t-boc-N-amido-PEG7-azide
- Purity
- 98%
- Packaging
- 1g
- Price
- $670
- Updated
- 2021/12/16
- Product number
- B-0918
- Product name
- BocNH-PEG7-CH2CH2N3
- Purity
- 95%
- Packaging
- 1g
- Price
- $495
- Updated
- 2021/12/16
BocNH-PEG7-CH2CH2N3 Chemical Properties,Usage,Production
Description
t-boc-N-amido-PEG7-azide is a PEG molecule with an azide(N3) group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Uses
Boc-NH-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-NH-PEG7-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
BocNH-PEG7-CH2CH2N3 Preparation Products And Raw materials
Raw materials
Preparation Products
BocNH-PEG7-CH2CH2N3 Suppliers
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View Lastest Price from BocNH-PEG7-CH2CH2N3 manufacturers
- Product
- Azido-PEG7-NHBoc 206265-96-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23