Azide-PEG7-Tos
- Product Name
- Azide-PEG7-Tos
- CAS No.
- 1418561-41-7
- Chemical Name
- Azide-PEG7-Tos
- Synonyms
- N3-PEG7-Tos;N3-PEG7-OTos;Azide-PEG7-Tos;Azido-PEG7-OTs;Azido-PEG7-Tos;20-Azido-3,6,9,12,15,18-hexaoxaicosyl 4-methylbenzenesulfonate;N3-PEG7-Tos/3,6,9,12,15,18-Hexaoxaeicosan-1-ol, 20-azido-, 1-(4-methylbenzenesulfonate)
- CBNumber
- CB53363859
- Molecular Formula
- C21H35N3O9S
- Formula Weight
- 505.58
- MOL File
- 1418561-41-7.mol
Azide-PEG7-Tos Property
- solubility
- Soluble in DMSO, DCM, DMF
N-Bromosuccinimide Price
- Product number
- BP-23441
- Product name
- Azide-PEG7-Tos
- Purity
- 98%
- Packaging
- 250mg
- Price
- $390
- Updated
- 2021/12/16
- Product number
- AS107837
- Product name
- N3-PEG7-Tos
- Purity
- 97%
- Packaging
- 250mg
- Price
- $401
- Updated
- 2021/12/16
- Product number
- AS107837
- Product name
- N3-PEG7-Tos
- Purity
- 97%
- Packaging
- 1g
- Price
- $869
- Updated
- 2021/12/16
- Product number
- B-1425
- Product name
- N3-PEG7-Tos
- Purity
- 97%
- Packaging
- 1g
- Price
- $605
- Updated
- 2021/12/16
Azide-PEG7-Tos Chemical Properties,Usage,Production
Description
Azide-PEG7-Tos is a PEG linker containing an azide group and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions.
Uses
Azide-PEG7-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG7-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azide-PEG7-Tos Preparation Products And Raw materials
Raw materials
Preparation Products
Azide-PEG7-Tos Suppliers
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- 400-164-7117 13681763483
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- +86-21-61629029
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- China
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- +1-781-999-5354; +17819995354
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- United States
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- China
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- 13303867194
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View Lastest Price from Azide-PEG7-Tos manufacturers
- Product
- Azido-PEG7-Tos 1418561-41-7
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >95.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23