Azido-PEG1-methyl ester
- Product Name
- Azido-PEG1-methyl ester
- CAS No.
- 1835759-80-2
- Chemical Name
- Azido-PEG1-methyl ester
- Synonyms
- Azido-PEG1-methyl ester
- CBNumber
- CB13162861
- Molecular Formula
- C6H11N3O3
- Formula Weight
- 173.17
- MOL File
- 1835759-80-2.mol
N-Bromosuccinimide Price
- Product number
- BP-22934
- Product name
- Azido-PEG1-methylester
- Purity
- 98%
- Packaging
- 100mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- BP-22934
- Product name
- Azido-PEG1-methylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $450
- Updated
- 2021/12/16
- Product number
- BP-22934
- Product name
- Azido-PEG1-methylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $660
- Updated
- 2021/12/16
- Product number
- BP-22934
- Product name
- Azido-PEG1-methylester
- Purity
- 98%
- Packaging
- 1g
- Price
- $980
- Updated
- 2021/12/16
Azido-PEG1-methyl ester Chemical Properties,Usage,Production
Description
Azido-PEG1-methyl ester is a crosslinker containing an azide group and a methyl ester. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
Azido-PEG1-methyl ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-methyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG1-methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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