Azido-PEG1-CH2CO2-NHS

Product Name: Azido-PEG1-CH2CO2-NHS
CAS No.: 1480545-09-2
Chemical Name: Azido-PEG1-CH2CO2-NHS
Synonyms: Azido-PEG1-CH2CO2-NHS;Azido-Peg1-CH2CO2-NH3;Azido-PEG1-CH2COO-NHS ester;Azido-PEG1-CH2COOH NHS Ester;2,5-dioxopyrrolidin-1-yl 2-(2-azidoethoxy)acetate
CBNumber: CB23373563
Molecular Formula: C8H10N4O5
Formula Weight: 242.19
MOL File: 1480545-09-2.mol

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Azido-PEG1-CH2CO2-NHS Property

solubility: Soluble in DMSO, DCM, DMF

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Hazard and Precautionary Statements (GHS)

Signal word: Warning

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-24047
Product name: Azido-PEG1-CH2CO2-NHS
Purity: 98%
Packaging: 100mg
Price: $280
Updated: 2021/12/16

BroadPharm

Product number: BP-24047
Product name: Azido-PEG1-CH2CO2-NHS
Purity: 98%
Packaging: 250mg
Price: $560
Updated: 2021/12/16

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Azido-PEG1-CH2CO2-NHS Chemical Properties,Usage,Production

Description

Azido-PEG1-CH2CO2-NHS is a PEG linker containing azide and NHS ester moieties. The hydrophilic PEG spacer increases the water solubility of compounds in aqueous media. The azide group can react with alkynes, BCN and DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

Azido-PEG1-CH2CO2-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG1-CH2CO2-NHS Preparation Products And Raw materials

Raw materials

Preparation Products

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Azido-PEG1-CH2CO2-NHS Suppliers

China 15 United States 2 Global 17

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-0431-80514535 19917294565
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Shaanxi borno biotechnology co., LTD

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Shanghai Minhan Pharmaceutical Technology Co., Ltd.

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Zhengzhou Akem Chemical Co., Ltd

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Beijing Jin Ming Biotechnology Co., Ltd.

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Affinity（Wuhan）Ltd.

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Shanghai Easy CDMO Co.,Ltd

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TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29257
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1480545-09-2, Azido-PEG1-CH2CO2-NHSRelated Search:

Ald-PEG5-Azide Azido-PEG1-methyl ester Azido-PEG1-methylamine Azido-PEG3-methyl ester Azido-PEG7-acid Azido-PEG5-PFP ester Azide-PEG7-Tos Azido-PEG4-beta-D-glucose Azidoethyl-SS-ethylamine

Azido-PEG1-CH2CO2-NHS

2,5-dioxopyrrolidin-1-yl 2-(2-azidoethoxy)acetate

Azido-PEG1-CH2COOH NHS Ester

Azido-PEG1-CH2COO-NHS ester

Azido-Peg1-CH2CO2-NH3

1480545-09-2