Azido-PEG4-alpha-D- mannose
- Product Name
- Azido-PEG4-alpha-D- mannose
- CAS No.
- 1632372-86-1
- Chemical Name
- Azido-PEG4-alpha-D- mannose
- Synonyms
- ADN72861;Azido-PEG4-α-D-mannose;Azido-PEG4-alpha-D- mannose;(2S,3S,4S,5S,6R)-2-(2-(2-(2-(2-Azidoethoxy)ethoxy)ethoxy)ethoxy)-6-(hydroxymethyl)tetrahydro-2Hpyran-3,4,5-triol
- CBNumber
- CB04849542
- Molecular Formula
- C14H27N3O9
- Formula Weight
- 381.38
- MOL File
- 1632372-86-1.mol
Azido-PEG4-alpha-D- mannose Property
- form
- Viscous Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- BP-23832
- Product name
- Azido-PEG4-alpha-D-mannose
- Purity
- 98%
- Packaging
- 50mg
- Price
- $320
- Updated
- 2021/12/16
- Product number
- BP-23832
- Product name
- Azido-PEG4-alpha-D-mannose
- Purity
- 98%
- Packaging
- 100mg
- Price
- $540
- Updated
- 2021/12/16
Azido-PEG4-alpha-D- mannose Chemical Properties,Usage,Production
Description
Azido-PEG4-alpha-D-glucose is a PEG linker containing azide group and D-glucose moieties. The azide group enables copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN. The hydrophilic PEG spacer increases solubility in aqueous media. D-glucose increases solubility in aqueous media and increases the selectivity of the PEGylation reaction.
Uses
Azido-PEG4-alpha-D-mannose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG4-alpha-D-mannose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG4-alpha-D- mannose Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Azido-PEG4-alpha-D- mannose manufacturers
- Product
- Azido-PEG4-alpha-D-mannose 1632372-86-1
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >98.00%
- Supply Ability
- 100mg
- Release date
- 2024-03-23