2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol

Product Name: 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
CAS No.: 168640-82-2
Chemical Name: 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
Synonyms: N?-PEG4-Ots;N3-PEG4-OTs;N3-PEG4-Tos;Azido-PEG4-Tos;Azido-PEG4-OTs;Azide-PEG4-Tos Azide-PEG4-Tos;11-Azido-3,6,9-trioxaundecanyl p-toluenesulfonate;2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate;2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol;N3-PEG4-Tos/Ethanol, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate)
CBNumber: CB51231413
Molecular Formula: C13H19N3O5S
Formula Weight: 0
MOL File: 168640-82-2.mol

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2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol Property

storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A926503
Product name: Azide-PEG4-Tos
Packaging: 5mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA07579
Product name: 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
Packaging: 25mg
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA07579
Product name: 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
Packaging: 50mg
Price: $80
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA07579
Product name: 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
Packaging: 100mg
Price: $130
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA07579
Product name: 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
Packaging: 250mg
Price: $250
Updated: 2021/12/16

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2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol Chemical Properties,Usage,Production

Description

Azide-PEG4-Tos is a heterofunctional crosslinker containing an azide (N3) group and a tosyl group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions. PEG spacer increases solubility in aqueous media.

Uses

Azide-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG4-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol Suppliers

China 49 India 1 United Kingdom 2 United States 4 Global 56

Beijing Ouhe Technology Co., Ltd

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View Lastest Price from 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol 168640-82-2
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2025-09-12

Xian confluore Biological Technology Co., Ltd.

Product: Azido-PEG4-Tos 168640-82-2
Price: US $0.00/g
Min. Order: 1g
Purity: >99.00%
Supply Ability: 1g
Release date: 2024-03-23

168640-82-2, 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanolRelated Search:

1-AZIDO-3,6,9-TRIOXAUNDECANE-11-OL Azido-PEG4-NHS Ester N3-PEG4-tBu 15-Azido-4,7,10,13-tetraoxapentadecanoic acid 1,14-Diazido-3,6,9,12-tetraoxatetradecane 22-Amino-5,8,11,14,17,20-hexaoxa-2-azadocosanoic acid 1,1-dimethylethyl ester 2-[2-(2-Azidoethoxy)ethoxy]ethanamine alpha, oMega-DisucciniMidyl hexaethylene glycol 2-(2-Azidoethoxy)ethanol H2N-PEG11-CH2CH2COOH N3-PEG3-tBu Acid-PEG3-mono-methyl ester Amino-PEG10-alcohol Azide-PEG4-Tos H2N-PEG3-CH2COOtBu alpha-aMine-oMega-propionic acid decaethylene glycol H2N-PEG12-tBu Azido-PEG7-azide

2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol

Azido-PEG4-Tos

2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate

11-Azido-3,6,9-trioxaundecanyl p-toluenesulfonate

N3-PEG4-Tos

Azido-PEG4-OTs

N3-PEG4-OTs

N3-PEG4-Tos/Ethanol, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate)

Azide-PEG4-Tos Azide-PEG4-Tos

N?-PEG4-Ots

168640-82-2

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