Azido-PEG7-acid

Product Name: Azido-PEG7-acid
CAS No.: 1446411-32-0
Chemical Name: Azido-PEG7-acid
Synonyms: N3-PEG7-CH2COOH;23-Azido-3,6,9,12,15,18,21-heptaoxatricosan-1-oic Acid;N3-PEG7-CH2COOH/3,6,9,12,15,18,21-Heptaoxatricosanoic acid, 23-azido-
CBNumber: CB45478192
Molecular Formula: C16H31N3O9
Formula Weight: 409.44
MOL File: 1446411-32-0.mol

More

Less

Azido-PEG7-acid Property

InChI: InChI=1S/C16H31N3O9/c17-19-18-1-2-22-3-4-23-5-6-24-7-8-25-9-10-26-11-12-27-13-14-28-15-16(20)21/h1-15H2,(H,20,21)
InChIKey: OHDHUWBOUOIMHQ-UHFFFAOYSA-N
SMILES: O(CCOCCOCC(=O)O)CCOCCOCCOCCOCCN=[N+]=[N-]

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Activate Scientific

Product number: AS106453
Product name: N3-PEG7-CH2COOH
Purity: 97%
Packaging: 100mg
Price: $184
Updated: 2021/12/16

Activate Scientific

Product number: AS106453
Product name: N3-PEG7-CH2COOH
Purity: 97%
Packaging: 1g
Price: $743
Updated: 2021/12/16

Acrotein

Product number: B-0905
Product name: N3-PEG7-CH2COOH
Purity: 97%
Packaging: 0.25g
Price: $247.5
Updated: 2021/12/16

More

Less

Azido-PEG7-acid Chemical Properties,Usage,Production

Uses

Azido-PEG7-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG7-CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Biological Activity

Azido-PEG7-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Azido-PEG7-acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Azido-PEG7-acid Suppliers

China 25 United States 1 Global 26

Ningxia Yiming Biomedical Technology Co., Ltd

Tel: 18754046789
Email: yiming@163.cn
Country: China
ProdList: 65
Advantage: 58

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

Shanghai Yihe Biological Technology Co., Ltd.

Tel: 021-68882955 17721395025
Fax: 021-68882955
Email: 2423903095@qq.com
Country: China
ProdList: 4992
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
Advantage: 58

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1615
Advantage: 58

Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 20405
Advantage: 58

Shanghai Minhan Pharmaceutical Technology Co., Ltd.

Tel: 17612188245
Fax: QQ 2816925681
Email: 2816925681@qq.com
Country: China
ProdList: 2989
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Affinity（Wuhan）Ltd.

Tel: 15841022315
Email: sales@affinitytech.cn
Country: China
ProdList: 3000
Advantage: 58

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 5061
Advantage: 58

1446411-32-0, Azido-PEG7-acidRelated Search:

Ald-PEG5-Azide Azido-PEG1-methyl ester Azido-PEG1-CH2CO2-NHS Azido-PEG1-methylamine Azido-PEG3-methyl ester Azido-PEG5-PFP ester Azide-PEG7-Tos Azido-PEG4-beta-D-glucose Azidoethyl-SS-ethylamine

N3-PEG7-CH2COOH

N3-PEG7-CH2COOH/3,6,9,12,15,18,21-Heptaoxatricosanoic acid, 23-azido-

23-Azido-3,6,9,12,15,18,21-heptaoxatricosan-1-oic Acid

1446411-32-0