Azido-PEG4-beta-D-glucose
- Product Name
- Azido-PEG4-beta-D-glucose
- CAS No.
- 1609083-15-9
- Chemical Name
- Azido-PEG4-beta-D-glucose
- Synonyms
- Azido-PEG4-β-D-glucose;Azido-PEG4-beta-D-glucose
- CBNumber
- CB63062357
- Molecular Formula
- C14H27N3O9
- Formula Weight
- 381.38
- MOL File
- 1609083-15-9.mol
Azido-PEG4-beta-D-glucose Property
- solubility
- Soluble in Water, DMSO, DMF
- form
- Oil
- color
- Light brown to brown
N-Bromosuccinimide Price
- Product number
- BP-22505
- Product name
- Azido-PEG4-beta-D-glucose
- Purity
- 98%
- Packaging
- 100mg
- Price
- $540
- Updated
- 2021/12/16
- Product number
- BP-22505
- Product name
- Azido-PEG4-beta-D-glucose
- Purity
- 98%
- Packaging
- 1g
- Price
- $2500
- Updated
- 2021/12/16
Azido-PEG4-beta-D-glucose Chemical Properties,Usage,Production
Description
Azido-PEG4-beta-D-glucose is a PEG linker containing one azide group and one D-glucose group. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media. D-glucose increases solubility in aqueous media and increases the selectivity of the PEGylation reaction.
Uses
Azido-PEG4-beta-D-glucose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG4-beta-D-glucose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG4-beta-D-glucose Preparation Products And Raw materials
Raw materials
Preparation Products
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