Azide-PEG7-Tos

Product Name: Azide-PEG7-Tos
CAS No.: 1418561-41-7
Chemical Name: Azide-PEG7-Tos
Synonyms: N3-PEG7-Tos;N3-PEG7-OTos;Azide-PEG7-Tos;Azido-PEG7-OTs;Azido-PEG7-Tos;20-Azido-3,6,9,12,15,18-hexaoxaicosyl 4-methylbenzenesulfonate;N3-PEG7-Tos/3,6,9,12,15,18-Hexaoxaeicosan-1-ol, 20-azido-, 1-(4-methylbenzenesulfonate)
CBNumber: CB53363859
Molecular Formula: C21H35N3O9S
Formula Weight: 505.58
MOL File: 1418561-41-7.mol

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Azide-PEG7-Tos Property

solubility: Soluble in DMSO, DCM, DMF

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23441
Product name: Azide-PEG7-Tos
Purity: 98%
Packaging: 250mg
Price: $390
Updated: 2021/12/16

Activate Scientific

Product number: AS107837
Product name: N3-PEG7-Tos
Purity: 97%
Packaging: 250mg
Price: $401
Updated: 2021/12/16

Activate Scientific

Product number: AS107837
Product name: N3-PEG7-Tos
Purity: 97%
Packaging: 1g
Price: $869
Updated: 2021/12/16

Acrotein

Product number: B-1425
Product name: N3-PEG7-Tos
Purity: 97%
Packaging: 1g
Price: $605
Updated: 2021/12/16

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Azide-PEG7-Tos Chemical Properties,Usage,Production

Description

Azide-PEG7-Tos is a PEG linker containing an azide group and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions.

Uses

Azide-PEG7-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG7-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azide-PEG7-Tos Preparation Products And Raw materials

Raw materials

Preparation Products

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Azide-PEG7-Tos Suppliers

China 23 United States 2 Global 25

Bide Pharmatech Ltd.

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Jinan elephant international trading co., LTD

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Amatek Scientific Co. Ltd.

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Xi'an Confluore Biological Technology Co., Ltd.

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Career Henan Chemica Co

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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Zhengzhou Convergence Chemical Co. LTD

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Zhengzhou Akem Chemical Co., Ltd

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Beijing Jin Ming Biotechnology Co., Ltd.

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Affinity（Wuhan）Ltd.

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Shanghai Haohong Scientific Co., Ltd.

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Shanghai Easy CDMO Co.,Ltd

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Shandong fen Boyu Biotechnology Co.,LTD

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TargetMol Chemicals Inc.

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Shanghai Yanfen Biochemical Technology Co.,LTD

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Shandong Dongde New Materials Co., Ltd

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Taizhou Chuanxu Pharmaceutical Technology Co., Ltd.

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Enzo Biochem Inc

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Henan Mengtai Pharmaceutical Technology Co., Ltd

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Xian confluore Biological Technology Co., Ltd.

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Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
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View Lastest Price from Azide-PEG7-Tos manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Azido-PEG7-Tos 1418561-41-7
Price: US $0.00/g
Min. Order: 1g
Purity: >95.00%
Supply Ability: 1g
Release date: 2024-03-23

1418561-41-7, Azide-PEG7-TosRelated Search:

BocNH-PEG7-CH2CH2N3 Azido-PEG7-NHS ester 1-Azido-23-bromo-3,6,9,12,15,18,21-heptaoxatricosane Amino-PEG8-azide Azido-PEG8-acid Azido-PEG7-hydrazide Azido-PEG7-azide Azido-PEG7-COOtBu N3-PEG7-OH Ald-PEG5-Azide Azido-PEG1-methyl ester Azido-PEG1-CH2CO2-NHS Azido-PEG1-methylamine Azido-PEG3-methyl ester Azido-PEG7-acid Azido-PEG5-PFP ester Azido-PEG4-beta-D-glucose Azidoethyl-SS-ethylamine

Azido-PEG7-OTs

Azide-PEG7-Tos

N3-PEG7-Tos

Azido-PEG7-Tos

N3-PEG7-Tos/3,6,9,12,15,18-Hexaoxaeicosan-1-ol, 20-azido-, 1-(4-methylbenzenesulfonate)

N3-PEG7-OTos

20-Azido-3,6,9,12,15,18-hexaoxaicosyl 4-methylbenzenesulfonate

1418561-41-7