ChemicalBook > CAS DataBase List > METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE

METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE

Product Name: METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE
CAS No.: 3337-59-5
Chemical Name: METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE
Synonyms: AURORA 17218;RARECHEM AL BF 0933;LABOTEST-BB LT00455579;METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE;METHYL-4-HYDROXY-3 5-DICHLOROBENZOATE;Methyl 3,5-Dichloro-4-Hydroxylbenzoate;4-HYDROXY-3,5-DICHLOROBENZOIC ACID METHYL ESTER;3,5-DICHLORO-4-HYDROXYBENZOIC ACID METHYL ESTER;4-HYDROXY-3,5-DICHLOROBENZOICACID METHYL ESTER 97%;3 5-DICHLORO-4-HYDROXYBENZOICACID METHYL ESTER 97%
CBNumber: CB5467194
Molecular Formula: C8H6Cl2O3
Formula Weight: 221.04
MOL File: 3337-59-5.mol

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METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE Property

Melting point:: 122-125°C
Boiling point:: 340.99°C (rough estimate)
Density: 1.4760 (rough estimate)
refractive index: 1.4800 (estimate)
storage temp.: Sealed in dry,Room Temperature
pka: 5.43±0.23(Predicted)
Appearance: Off-white to pink Solid
CAS DataBase Reference: 3337-59-5(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC

Product number: M301405
Product name: Methyl3,5-dichloro-4-hydroxybenzoate
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: M301405
Product name: Methyl3,5-dichloro-4-hydroxybenzoate
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Matrix Scientific

Product number: 114629
Product name: Methyl 3,5-dichloro-4-hydroxybenzoate
Purity: 97%
Packaging: 25g
Price: $74
Updated: 2021/12/16

Matrix Scientific

Product number: 114629
Product name: Methyl 3,5-dichloro-4-hydroxybenzoate
Purity: 97%
Packaging: 1g
Price: $10
Updated: 2021/12/16

Matrix Scientific

Product number: 114629
Product name: Methyl 3,5-dichloro-4-hydroxybenzoate
Purity: 97%
Packaging: 5g
Price: $22
Updated: 2021/12/16

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METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE Chemical Properties,Usage,Production

Synthesis

99-76-3

3337-59-5

The general procedure for the synthesis of methyl 3,5-dichloro-4-hydroxybenzoate from methyl nipagin was as follows: 4-hydroxybenzoic acid (0.2 g; 1.3 mmol) was mixed with N-chlorosuccinimide (0.37 g; 2.76 mmol) in anhydrous dichloromethane (15 ml) at room temperature, followed by the addition of titanium tetrachloride (0.1 ml; 0.9 mmol) . The reaction mixture was stirred for 5 hours. After completion of the reaction, ice (about 10 g) was added and stirring was continued for 30 min at room temperature. The mixture was diluted with ethyl acetate to 100 ml. The organic phase was separated, washed sequentially with water (2 x 10 ml) and brine (10 ml), dried over anhydrous magnesium sulfate and filtered, and the filtrate was concentrated to dryness. The residue was purified by silica gel column chromatography (dichloromethane as eluent) to afford methyl 3,5-dichloro-4-hydroxybenzoate (0.19 g; 65% yield) as a colorless solid. The 1H-NMR (CDCl3) data were as follows: δ 7.96 (s, 2H), 6.18 (s, 1H), 3.89 (s, 3H).

References

[1] Patent: WO2014/63199, 2014, A1. Location in patent: Page/Page column 89
[2] Gazzetta Chimica Italiana, 1899, vol. 29 I, p. 387,388

METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE Suppliers

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View Lastest Price from METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE 3337-59-5
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-11

Shaanxi Dideu Medichem Co. Ltd

Product: METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE 3337-59-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-07-11

Career Henan Chemical Co

Product: METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE 3337-59-5
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: JD 800
Release date: 2019-09-02

3337-59-5, METHYL 3,5-DICHLORO-4-HYDROXYBENZOATERelated Search:

ETHYL 3,5-DICHLORO-4-HYDROXYBENZOATE METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE 3,5-DICHLOROBENZOIC ACID METHYL ESTER 3,5-Dichloro-4-hydroxybenzoic acid GANGALEOIDIN LEOIDIN(SH) Avilamycin B 3,5-DICHLORO-4-HYDROXYBENZOIC ACID PROPYL ESTER 3,5-DICHLORO-4-METHOXYBENZOIC ACID ETHYL ESTER avilamycin A Avilamycin METHYL 3,5-DICHLORO-4-METHOXYBENZOATE flambamycin ETHYL 3,5-DICHLORO-4-PROPOXYBENZOATE Tiacumicin B N-BUTYL-3,5-DICHLORO-4-METHOXYENZOATE ETHYL 3,5-DICHLORO-4-HYDROXYBENZOATE HYD RATE, 98% METHYL-3,5-DICHLORO-4-HYDROXYBENZOATE HEMIHYDRATE,METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE MONOHYDRATE,METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE HYDRATE

Methyl 3,5-Dichloro-4-Hydroxylbenzoate

RARECHEM AL BF 0933

3,5-DICHLORO-4-HYDROXYBENZOIC ACID METHYL ESTER

4-HYDROXY-3,5-DICHLOROBENZOIC ACID METHYL ESTER

AURORA 17218

METHYL-4-HYDROXY-3 5-DICHLOROBENZOATE

METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE

LABOTEST-BB LT00455579

3 5-DICHLORO-4-HYDROXYBENZOICACID METHYL ESTER 97%

4-HYDROXY-3,5-DICHLOROBENZOICACID METHYL ESTER 97%

Benzoic acid, 3,5-dichloro-4-hydroxy-, methyl ester

3337-59-5

Cl2C6H2OHCOOCH3

Phenylacetic acid

Acids & Esters

Aromatic Esters

Chlorine Compounds

Phenols