METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE
- Product Name
- METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE
- CAS No.
- 3337-59-5
- Chemical Name
- METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE
- Synonyms
- AURORA 17218;RARECHEM AL BF 0933;LABOTEST-BB LT00455579;METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE;METHYL-4-HYDROXY-3 5-DICHLOROBENZOATE;Methyl 3,5-Dichloro-4-Hydroxylbenzoate;4-HYDROXY-3,5-DICHLOROBENZOIC ACID METHYL ESTER;3,5-DICHLORO-4-HYDROXYBENZOIC ACID METHYL ESTER;4-HYDROXY-3,5-DICHLOROBENZOICACID METHYL ESTER 97%;3 5-DICHLORO-4-HYDROXYBENZOICACID METHYL ESTER 97%
- CBNumber
- CB5467194
- Molecular Formula
- C8H6Cl2O3
- Formula Weight
- 221.04
- MOL File
- 3337-59-5.mol
METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE Property
- Melting point:
- 122-125°C
- Boiling point:
- 340.99°C (rough estimate)
- Density
- 1.4760 (rough estimate)
- refractive index
- 1.4800 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 5.43±0.23(Predicted)
- Appearance
- Off-white to pink Solid
- CAS DataBase Reference
- 3337-59-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- M301405
- Product name
- Methyl3,5-dichloro-4-hydroxybenzoate
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- M301405
- Product name
- Methyl3,5-dichloro-4-hydroxybenzoate
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 114629
- Product name
- Methyl 3,5-dichloro-4-hydroxybenzoate
- Purity
- 97%
- Packaging
- 25g
- Price
- $74
- Updated
- 2021/12/16
- Product number
- 114629
- Product name
- Methyl 3,5-dichloro-4-hydroxybenzoate
- Purity
- 97%
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- 114629
- Product name
- Methyl 3,5-dichloro-4-hydroxybenzoate
- Purity
- 97%
- Packaging
- 5g
- Price
- $22
- Updated
- 2021/12/16
METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE Chemical Properties,Usage,Production
Synthesis
99-76-3
3337-59-5
The general procedure for the synthesis of methyl 3,5-dichloro-4-hydroxybenzoate from methyl nipagin was as follows: 4-hydroxybenzoic acid (0.2 g; 1.3 mmol) was mixed with N-chlorosuccinimide (0.37 g; 2.76 mmol) in anhydrous dichloromethane (15 ml) at room temperature, followed by the addition of titanium tetrachloride (0.1 ml; 0.9 mmol) . The reaction mixture was stirred for 5 hours. After completion of the reaction, ice (about 10 g) was added and stirring was continued for 30 min at room temperature. The mixture was diluted with ethyl acetate to 100 ml. The organic phase was separated, washed sequentially with water (2 x 10 ml) and brine (10 ml), dried over anhydrous magnesium sulfate and filtered, and the filtrate was concentrated to dryness. The residue was purified by silica gel column chromatography (dichloromethane as eluent) to afford methyl 3,5-dichloro-4-hydroxybenzoate (0.19 g; 65% yield) as a colorless solid. The 1H-NMR (CDCl3) data were as follows: δ 7.96 (s, 2H), 6.18 (s, 1H), 3.89 (s, 3H).
References
[1] Patent: WO2014/63199, 2014, A1. Location in patent: Page/Page column 89
[2] Gazzetta Chimica Italiana, 1899, vol. 29 I, p. 387,388
METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE Suppliers
- Tel
- --
- Fax
- --
- labchem-tec@wako-chem.co.jp
- Country
- Japan
- ProdList
- 6819
- Advantage
- 80
View Lastest Price from METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE manufacturers
- Product
- METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE 3337-59-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-11
- Product
- METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE 3337-59-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-07-11
- Product
- METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE 3337-59-5
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 800
- Release date
- 2019-09-02