Indeloxazine hydrochloride
- Product Name
- Indeloxazine hydrochloride
- CAS No.
- 65043-22-3
- Chemical Name
- Indeloxazine hydrochloride
- Synonyms
- Noin;Elen;CI 874;CI874l;CI-874l;YM 08054;YM 08054-1;Indeloxazine HCl;Indeloxazine hydrochloride;Indeloxadine hydrochloride
- CBNumber
- CB5481835
- Molecular Formula
- C14H18ClNO2
- Formula Weight
- 267.75
- MOL File
- 65043-22-3.mol
Indeloxazine hydrochloride Property
- Melting point:
- 169-170°; mp 155-156°
- storage temp.
- Sealed in dry,Room Temperature
Safety
- RIDADR
- 3249
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Toxicity
- LD50 in mice (mg/kg): 47 i.v. (Tachikawa)
N-Bromosuccinimide Price
- Product number
- API0002992
- Product name
- INDELOXAZINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $577.5
- Updated
- 2021/12/16
- Product number
- 35515
- Product name
- 2-(((1H-Inden-7-yl)oxy)methyl)morpholineHCl
- Purity
- 95+%
- Packaging
- 1g
- Price
- $1280
- Updated
- 2021/12/16
- Product number
- CD33000169
- Product name
- IndeloxazineHydrochloride
- Purity
- 95+%
- Packaging
- 1g
- Price
- $772
- Updated
- 2021/12/16
Indeloxazine hydrochloride Chemical Properties,Usage,Production
Description
Indeloxazine hydrochloride is a nootropic indicated for the treatment of senile dementia. In animal models indeloxazine reportedly enhances brain energy metabolism and monoamine content; its claimed protective effect on ischemia-induced amnesia is supported by the prolonged step-through latency in passive avoidance tests.
Chemical Properties
Polycrystalline compounds: pale yellow needle-like (needles) crystals from methanol, melting point 169-170 ℃: colorless needle-like (acicular) crystals from acetone, melting point 155-156 ℃. Acute toxicity LD50 mice (mg/kg): 47 IV. (+)-configuration: crystallized from ethanol, melting point 112~113°C. [α]D21+4.9° (C=5, methanol). (-)-configuration: crystallized from isopropanol, melting point 142~142.5°C. [α]D20-4.9° (C=5, methanol).
Originator
Yamanouchi (Japan)
Uses
Antidepressant.
brand name
Elen
Metabolic pathway
After oral administration of indeloxazine hydrochloride to rats, two conjugates, which are labile to a- glucosidase hydrolysis but refractory to b-glucosidase, are isolated from the urine and identified as a-D- glucopyranosides of trans-4-(2-morpholinylmethoxy)- 1,2-indandiol and trans-6-[[(1,2-dihydroxy-4- indanyl)oxy]-methyl]-3-morpholinone.
Indeloxazine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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