Triethyl acetyl citrate
- Product Name
- Triethyl acetyl citrate
- CAS No.
- 77-89-4
- Chemical Name
- Triethyl acetyl citrate
- Synonyms
- ACETYL TRIETHYL CITRATE;ATEC;O-AcetyL;triethyl 2-acetoxypropane-1,2,3-tricarboxylate;Uniplex 82;Triethyl O;citroflexa2;Citroflex A 2;Trithylcitratc;ethyl acetylcitrate
- CBNumber
- CB5483819
- Molecular Formula
- C14H22O8
- Formula Weight
- 318.32
- MOL File
- 77-89-4.mol
Triethyl acetyl citrate Property
- Melting point:
- -42°C
- Boiling point:
- 228-229 °C/100 mmHg (lit.)
- Density
- 1.136 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.439(lit.)
- Flash point:
- >230 °F
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble 1 in 140 of water; miscible with acetone, ethanol, and propan-2-ol.
- color
- Colourless
- Odor
- odorless
- BRN
- 1804947
- LogP
- 2.170 (est)
- CAS DataBase Reference
- 77-89-4(CAS DataBase Reference)
- NIST Chemistry Reference
- 1,2,3-Propanetricarboxylic acid, 2-acetoxy-, triethyl ester(77-89-4)
- EPA Substance Registry System
- 1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, triethyl ester (77-89-4)
Safety
- Safety Statements
- 23-24/25
- WGK Germany
- 1
- RTECS
- GE8225000
- HS Code
- 2918150000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 388351
- Product name
- Triethyl 2-acetylcitrate
- Purity
- 99%
- Packaging
- 500ml
- Price
- $61.8
- Updated
- 2024/03/01
- Product number
- 1009923
- Product name
- Acetyltriethyl citrate
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 500mg
- Price
- $450
- Updated
- 2022/05/15
- Product number
- A0086
- Product name
- Triethyl O-Acetylcitrate
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $33
- Updated
- 2024/03/01
- Product number
- A0086
- Product name
- Triethyl O-Acetylcitrate
- Purity
- >97.0%(GC)
- Packaging
- 500g
- Price
- $68
- Updated
- 2024/03/01
- Product number
- PHR1157
- Product name
- Triethyl 2-acetylcitrate
- Purity
- Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging
- 1g
- Price
- $170
- Updated
- 2024/03/01
Triethyl acetyl citrate Chemical Properties,Usage,Production
Chemical Properties
Acetyltriethyl citrate occurs as a clear, odorless, practically colorless oily liquid.
Uses
ATEC is produced by the reaction of citric acid triethyl ester with acetic acid anhydride. It is used as a solvent plasticizer for cellulose nitrate and cellulose acetate.
Uses
Triethyl O-Acetylcitrate is used in the preparation of poly(lactic) acid biodegradable and flexible films, acting as a plasticizer. Also used in the synthesis of control-release capsules containing polymeric coatings.
Definition
Aqueous-based pharmaceutical coat- ings.
Production Methods
Acetyltriethyl citrate is prepared by the esterification of citric acid with ethanol followed by acylation with acetic anhydride.
General Description
Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Triethyl 2-acetylcitrate is widely used in hydrophilic adhesives for medications and in biodegradable composition for papermaking and nonwoven production.
Pharmaceutical Applications
Acetyltriethyl citrate is used to plasticize polymers in formulated pharmaceutical coatings. The coating applications include capsules, tablets, beads and granules for taste masking, immediate release, sustained-release and enteric formulations. It is also used in diffusion-controlled release drug delivery systems.
Safety
Acetyltriethyl citrate is used in oral pharmaceutical formulations
and is generally regarded as a nontoxic and nonirritating material.
However, ingestion of large quantities may be harmful.
LD50 (cat, oral): 8.5 g/kg
LD50 (mouse, IP): 1.15 g/kg
LD50 (rat, oral): 7 g/kg
storage
Acetyltriethyl citrate should be stored in dry, closed containers at temperatures not exceeding 388℃. When stored in accordance with these conditions, acetyltriethyl citrate is a stable product.
Incompatibilities
Acetyltriethyl citrate is incompatible with strong alkalis and oxidizing materials.
Regulatory Status
Approved in the USA for direct food contact in food films.
Triethyl acetyl citrate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Triethyl acetyl citrate manufacturers
- Product
- Acetyl Triethyl Citrate 77-89-4
- Price
- US $200.00-95.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-04-25
- Product
- Triethyl acetyl citrate 77-89-4
- Price
- US $100.00/kg
- Min. Order
- 1kg
- Purity
- 98
- Supply Ability
- 4000
- Release date
- 2024-04-25
- Product
- Triethyl acetyl citrate 77-89-4
- Price
- US $20.00-1.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-10-13