4-Nitrobenzyl bromide
- Product Name
- 4-Nitrobenzyl bromide
- CAS No.
- 100-11-8
- Chemical Name
- 4-Nitrobenzyl bromide
- Synonyms
- 1-(BROMOMETHYL)-4-NITROBENZENE;PARA NITRO BENZYL BROMIDE;P-NITROBENZYL BROMIDE;4NBB;Nitrobenzyl bromide;4-Nitrobenzyl;AKOS BBS-00004545;Nitrobenzyl broMid;p-Nitobenzylbromide;Nitro broMine benzyl
- CBNumber
- CB5485712
- Molecular Formula
- C7H6BrNO2
- Formula Weight
- 216.03
- MOL File
- 100-11-8.mol
4-Nitrobenzyl bromide Property
- Melting point:
- 98 °C
- Boiling point:
- 265.51°C (rough estimate)
- Density
- 1.6841 (rough estimate)
- refractive index
- 1.6120 (estimate)
- storage temp.
- Store at RT.
- solubility
- soluble in Chloroform, Ethyl Acetate
- form
- Crystalline Powder
- color
- Light yellow to beige
- Water Solubility
- It hydrolyzes in water. Soluble in alcohol and ether.
- BRN
- 742796
- Stability:
- Stable. Incomaptible with bases, amines, oxidizing agents, alcohols. May be moisture sensitive. Corrodes steel.
- CAS DataBase Reference
- 100-11-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzene, 1-(bromomethyl)-4-nitro-(100-11-8)
- EPA Substance Registry System
- Benzene, 1-(bromomethyl)-4-nitro- (100-11-8)
Safety
- Hazard Codes
- C,Xi
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 3261 8/PG 2
- WGK Germany
- 3
- RTECS
- XS7967000
- F
- 10-19-21
- Hazard Note
- Irritant/Corrosive
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29049085
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- N13054
- Product name
- 4-Nitrobenzyl bromide
- Purity
- 99%
- Packaging
- 25g
- Price
- $47.6
- Updated
- 2024/03/01
- Product number
- N13054
- Product name
- 4-Nitrobenzyl bromide
- Purity
- 99%
- Packaging
- 100g
- Price
- $66.6
- Updated
- 2024/03/01
- Product number
- N0181
- Product name
- 4-Nitrobenzyl Bromide
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $28
- Updated
- 2023/06/20
- Product number
- N0181
- Product name
- 4-Nitrobenzyl Bromide
- Purity
- >98.0%(GC)(T)
- Packaging
- 100g
- Price
- $87
- Updated
- 2023/06/20
- Product number
- A15236
- Product name
- 4-Nitrobenzyl bromide, 97+%
- Packaging
- 25g
- Price
- $42.1
- Updated
- 2023/06/20
4-Nitrobenzyl bromide Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powde
Uses
4-Nitrobenzyl bromide is used in the synthesis of di and tri-substituted azoles. It is also used in the preparation of N6-Benzyladenosine-5?-uronamides as selective A3 adenosine agonists.
Definition
ChEBI: A C-nitro compound that consists of nitrobenzene bearing a bromomethyl substituent at the para-position.
Purification Methods
Recrystallise the bromide four times from absolute EtOH, then twice from cyclohexane/hexane/*benzene (1:1:1), followed by sublimation at 0.1mm and final recrystallisation from the same solvent mixture. [Lichtin & Rao J Am Chem Soc 83 2417 1961.] It has also been crystallised from pet ether (b 80-100o, 10mL/g, charcoal). It slowly decomposes even when stored in a desiccator in the dark. IRRITANT. [Beilstein 5 IV 861.]