ChemicalBook > CAS DataBase List > β-Glycerophosphate disodium salt pentahydrate

β-Glycerophosphate disodium salt pentahydrate

Product Name
β-Glycerophosphate disodium salt pentahydrate
CAS No.
13408-09-8
Chemical Name
β-Glycerophosphate disodium salt pentahydrate
Synonyms
trichloromethyl carbonochloridate;β-Glycerophosphate;β-Glycerophosphate (sodium salt hydrate);SodiuM 1,3-dihydroxypropan-2-yl phosphate;β-Glycerophosphate disodium salt pentahydrate;β-Glycerol phosphate disodium salt pentahydrate;Sodium B Glycerophosphate;Disodium β-glycerol phosphate;beta-Glycerophosphate, 200mM soln;Sodium--glycerophosphate, GR 99%+
CBNumber
CB5502680
Molecular Formula
C3H12NaO7P
Formula Weight
214.09
MOL File
13408-09-8.mol
More
Less

β-Glycerophosphate disodium salt pentahydrate Property

Melting point:
>300°C
storage temp. 
2-8°C
solubility 
H2O: 0.1 g/mL, clear, colorless
form 
White powder
color 
Whiteto Off-White
Water Solubility 
Soluble in water.
Merck 
14,8622
BRN 
3744328
Stability:
Hygroscopic
InChI
InChI=1S/C3H9O6P.Na.H2O.H/c4-1-3(2-5)9-10(6,7)8;;;/h3-5H,1-2H2,(H2,6,7,8);;1H2;
InChIKey
PEMUISUYOHQFQH-UHFFFAOYSA-L
SMILES
O(P(O)(O)=O)C(CO)CO.[NaH].O
More
Less

Safety

WGK Germany 
3
RTECS 
UA0600000
F 
10-21
TSCA 
Yes
HS Code 
29199000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
35675
Product name
β-Glycerophosphate, Disodium Salt, Pentahydrate - CAS 13408-09-8 - Calbiochem
Purity
Aphosphategroupdonorinmatrixmineralizationstudiesthatactsasaprotein
Packaging
50g
Price
$56.2
Updated
2024/03/01
Sigma-Aldrich
Product number
35675
Product name
β-Glycerophosphate, Disodium Salt, Pentahydrate - CAS 13408-09-8 - Calbiochem
Purity
Aphosphategroupdonorinmatrixmineralizationstudiesthatactsasaprotein
Packaging
100g
Price
$85.2
Updated
2024/03/01
Sigma-Aldrich
Product number
35675
Product name
β-Glycerophosphate, Disodium Salt, Pentahydrate - CAS 13408-09-8 - Calbiochem
Purity
Aphosphategroupdonorinmatrixmineralizationstudiesthatactsasaprotein
Packaging
250g
Price
$187
Updated
2024/03/01
TCI Chemical
Product number
D3964
Product name
Disodium beta-Glycerophosphate Pentahydrate[for Biochemical Research]
Purity
>95.0%(T)
Packaging
1g
Price
$34
Updated
2024/03/01
TCI Chemical
Product number
D3964
Product name
Disodium beta-Glycerophosphate Pentahydrate[for Biochemical Research]
Purity
>95.0%(T)
Packaging
5g
Price
$71
Updated
2024/03/01
More
Less

β-Glycerophosphate disodium salt pentahydrate Chemical Properties,Usage,Production

Description

β-Glycerophosphate is a protein phosphatase inhibitor that acts as a phosphate group donor in matrix mineralization studies. It promotes bone matrix mineralization when delivered to osteoblasts by providing a source of phosphate ions. β-Glycerophosphate (10 mM) accelerates calcification of cultured vascular smooth muscle cells through an alkaline phosphatase-related mechanism.

Chemical Properties

Solid

Uses

β-Glycerol Phosphate was shown to have promoted mineralization in vitro by modulating bone cell metabolic activity and/or serving as a local source of inorganic phosphate ions.

Uses

Sodium β-glycerophosphate pentahydrate is used as a phosphatase inhibitor. It promotes bone matrix mineralization while delivering to osteoblasts by providing a source of phosphate ions. It is used in the development of hydrogels and scaffolds, which finds applications in tissue engineering and cell growth. It is used as an additive in isolation mediums by providing phosphate ions to isolate. It is utilized to promote mineralization in vitro by modulating bone cell metabolic activity.

General Description

A phosphate group donor in matrix mineralization studies. Accelerates calcification in vascular smooth muscle cells. Also acts as a protein phosphatase inhibitor.

Biochem/physiol Actions

Beta-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It functions as an organic phosphate donor and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells. BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression

Purification Methods

Crystallise it from water. [Attwood et al. Biochem J 253 389 1988, Beilstein 1 IV 2766.]

References

[1]. chung ch, golub ee, forbes e, et al. mechanism of action of beta-glycerophosphate on bone cell mineralization. calcif tissue int. 1992 oct;51(4):305-11.
[2]. fujimoto h, mabuchi i. isolation of cleavage furrows from eggs of regular sea urchins and identification of furrow-specific proteins. j biochem. 1997 sep;122(3):518-24.
[3]. lecanda f, avioli lv, cheng sl. regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2. j cell biochem. 1997 dec 1;67(3):386-96.
[4]. shioi a, nishizawa y, jono s, et al. beta-glycerophosphate accelerates calcification in cultured bovine vascular smooth muscle cells. arterioscler thromb vasc biol. 1995 nov;15(11):2003-9.

β-Glycerophosphate disodium salt pentahydrate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

β-Glycerophosphate disodium salt pentahydrate Suppliers

Americas 1 Canada 2 China 177 Europe 1 France 1 Germany 4 India 15 Japan 1 Poland 1 Switzerland 3 United Kingdom 4 United States 25 Global 235
Anhui Shite Pharmaceutical Technology Co., LTD
Tel
0555-8228058 13621628489
Fax
0512-63261912
Email
sales1@stepuppharm.com
Country
China
ProdList
229
Advantage
55
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19179
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Nanjing MeiBo Biological Technology Co., Ltd.
Tel
025-58619198
Fax
025-58619197
Email
sales@mbbio.com
Country
China
ProdList
319
Advantage
60
Tangshan Moneide Trading Co., Ltd.
Tel
0315-8309571 15633399667
Fax
+86-315-7726572
Email
sales@moneidechem.com
Country
China
ProdList
704
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4554
Advantage
62
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9347
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Shanghai Ruji Biology Technology Co., Ltd.
Tel
+86-21-65211385-8001 36031160
Fax
+86-21-65211385-8004
Email
sales@shruji.com
Country
China
ProdList
3224
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
7295
Advantage
60
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Watec Laboratories, Inc.
Tel
18602586511
Fax
0519-85267382
Email
info@wateclaboratories.com
Country
China
ProdList
143
Advantage
60
Beijing NuoqiYa Biotechnology Co., Ltd.
Tel
4000-819-385 010-62329685 13718666987
Fax
010-62340519
Country
China
ProdList
1971
Advantage
55
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7977
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
VWR(Shanghai) Co., Ltd
Tel
400-821-8006
Fax
+86-21-58558801
Email
info_china@vwr.com
Country
China
ProdList
3040
Advantage
75
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9941
Advantage
58
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
Raw material medicin reagent co.,Ltd
Tel
Email
sales@njromanme.com
Country
China
ProdList
4529
Advantage
58
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Grader reagent
Tel
18221735425
Email
sales@xinpingchem.com
Country
China
ProdList
9942
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29785
Advantage
68
Shanghai YiWen Pharmaceutical Co., Ltd.
Tel
13621628489
Email
1322392736@qq.com
Country
China
ProdList
263
Advantage
58
Shanghai Yihe Biological Technology Co., Ltd.
Tel
17721395025
Fax
021-68882955
Email
2423903095@qq.com
Country
China
ProdList
4066
Advantage
58
Shenzhen Sendi Biological Technology Co., Ltd.
Tel
18124570582 TEL：0755-23574479 2355327139
Fax
0755-23229476 QQ: 2355327139
Email
siliao02@yccreate.com
Country
China
ProdList
6116
Advantage
58
Anhui kuer Bioengineering Co., Ltd
Tel
0551-65171243 13856024262
Email
kuer@kuerhuaxue.com
Country
China
ProdList
2997
Advantage
55
Guangzhou Kafen Biotech Co.,Ltd
Tel
18029243487 2355327168
Fax
020-31121510
Email
gy@yccreate.com
Country
China
ProdList
4749
Advantage
55
Taian Jiaye Biotechnology Co.Ltd
Tel
13127280945
Email
285424065@qq.com
Country
China
ProdList
9976
Advantage
55
More
Less

View Lastest Price from β-Glycerophosphate disodium salt pentahydrate manufacturers

Career Henan Chemical Co
Product
BETA-GLYCEROL PHOSPHATE DISODIUM SALT 13408-09-8
Price
US $2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
ask
Release date
2018-12-22
Career Henan Chemical Co
Product
N-(1-NAPHTHYL)-3-AMINOPROPANESULFONIC ACID SODIUM SALT 13408-09-8
Price
US $2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
ask
Release date
2018-12-22
Career Henan Chemical Co
Product
PHENYL PHOSPHATE DISODIUM SALT 13408-09-8
Price
US $1.00/KG
Min. Order
1KG
Purity
95%-99%
Supply Ability
1000kg
Release date
2018-12-24

13408-09-8, β-Glycerophosphate disodium salt pentahydrateRelated Search:

Bromothymol Blue CPNQ Disodium beta-glycerophosphate pentahydrate Ruthenium(III) chloride hydrate 5-Bromo-4-chloro-3-indolyl phosphate p-toluidine salt Sodium 3-phosphoglycerate β-Hydroxybutyrate (β-HB) Colorimetric Assay Kit β-Hydroxybutyrate (Ketone Body) Colorimetric Assay Kit β-Hydroxybutyrate (Ketone Body) Fluorometric Assay Kit β-Glycerophosphate disodium salt β-Glycerophosphate (BGP) Disodium Disodium β-glycerophosphate hydrate DEOXYRIBONUCLEIC ACID Glycerol BETA-GLYCEROL PHOSPHATE DISODIUM SALT PENTAHYDRATE

  • Sodium B Glycerophosphate
  • BETA-GLYCEROL PHOSPHATE DISODIUM SALT
  • Disodium β-glycerol phosphate
  • BLUE DUO PROTEIN MARKER, LOW RANGE BIOT
  • beta-Glycerophosphate, disodium salt pentahydrate, max. 2% alpha
  • BETA-GLYCEROL PHOSPHATE DISODIUM SAL
  • Disodium β-glycerol phosphate Glycerol 2-Phosphate Disodium Salt β-Glycerophosphoric Acid Disodium Salt
  • Disodium β-Glycerophosphate Pentahydrate
  • .beta.-Glycerophosphate (sodium salt hydrate)
  • β-Glycerol phosphate disodium salt pentahydrate
  • BETA-GLYCEROPHOSPHATE DISODIUM SALT
  • SODIUM SS-GLYCEROPHOSPHATE PENTAHYDRATE
  • SODIUM B-GLYCEROPHOSPHATE PENTAHYDRATE
  • á-glycerol phosphate disodium salt pentahydrate
  • sodium á-glycerophosphate pentahydrate
  • β-Glycerol phosphate pentahydrate disodium salt
  • Disodium beta-glycerol phosphate pentahydrate
  • beta-Glycerophosphoric acid disodium salt pentahydrate
  • chlorocarbonic acid trichloromethyl ester
  • trichloromethyl carbonochloridate
  • β-Glycerol phosphate disodium salt pentahydrate,Disodium β-glycerol phosphate
  • b-Glycerophosphate disodium salt pentahydrate 97+%
  • DisodiuM beta-Glycerophosphate Pentahydrate [for BiocheMical Research]
  • DisodiuM β-Glycerophosphate Pentahydrate [for BiocheMical Research]
  • SodiuM 1,3-dihydroxypropan-2-yl phosphate
  • Two sodiuMglycerophosphatefivewater
  • DisodiuM β-glycerol phosphate pentahydrate
  • SodiuM 1,3-dihydroxypropan-2-yl phosphate pentahydrate
  • β-glycerophosphoric acid disodium salt pentahydrate
  • Disodiumβ-GlycerophosphatePentahydrate[forBiochemicalResearch]&gt
  • Disodiumβ-GlycerophosphatePentahydrate&gt
  • BETA- LYCEROL PHOSPHATE DISODIUM SALT
  • β-Glycerophosphate (sodium salt hydrate)
  • β-Glycerophosphate disodium salt pentahydrate
  • beta-Glycerophosphate, 200mM soln
  • β-Glycerol phosphate disodium salt
  • beta-Glycerophosphate disodium salt 5-hydrate
  • β-Glycerophosphate
  • Disodium β-Glycerophosphate Pentahydrate
  • disodium 2-(phosphonatooxy)propane-1,3-diol
  • Sodium--glycerophosphate, GR 99%+
  • -β-Glycerol Phosphate Disodium Salt Pentahydrate
  • Disodium β-Glycerophosphate Pentahydrate [for Biochemical Research]
  • Sodium Beta-Glycerophosphate Pentahydrate, 98-102%, Extra Pure, SLR, Fisher Chemical
  • SODIUM-β-GLYCEROPHOSPHATE PENTAHYDRATE AR
  • 1,2,3-Propanetriol, 2-(dihydrogen phosphate), sodium salt, hydrate (1:2:5)
  • β-glycerophosphate Sodium Solution
  • Diso diump-Glycerophosphate Pentahydrate
  • 13408-09-8
  • HOCH22CHOPOONa25H2O
  • C3H7O6PNaH2O
  • buffer