ChemicalBook > CAS DataBase List > m-PEG9-COOH

m-PEG9-COOH

Product Name: m-PEG9-COOH
CAS No.: 2576495-35-5
Chemical Name: m-PEG9-COOH
Synonyms: m-PEG9-COOH;4,7,10,13,16,19,22,25,28-Nonaoxanonacosanoic acid;2,5,8,11,14,17,20,23,26-Nonaoxanonacosan-29-oic acid;mPEG8-CH2CH2COOH/4,7,10,13,16,19,22,25,28-Nonaoxanonacosanoic acid;3-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
CBNumber: CB55478210
Molecular Formula: C20H40O11
Formula Weight: 456.52
MOL File: 2576495-35-5.mol

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m-PEG9-COOH Property

Boiling point:: 536.3±50.0 °C(Predicted)
Density: 1.111±0.06 g/cm3(Predicted)
storage temp.: 2-8°C, sealed storage, away from moisture
pka: 4.28±0.10(Predicted)
form: Liquid
color: Colorless to light yellow
InChI: InChI=1S/C20H40O11/c1-23-4-5-25-8-9-27-12-13-29-16-17-31-19-18-30-15-14-28-11-10-26-7-6-24-3-2-20(21)22/h2-19H2,1H3,(H,21,22)
InChIKey: HVDSDOIAPZITDA-UHFFFAOYSA-N
SMILES: C(O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOC

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Hazard and Precautionary Statements (GHS)

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m-PEG9-COOH Chemical Properties,Usage,Production

Uses

m-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

m-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

m-PEG9-COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from m-PEG9-COOH manufacturers

LAURENT

Product: mPEG8-CH2CH2COOH 2576495-35-5
Price: US $221.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 500kg
Release date: 2025-11-20

Xian confluore Biological Technology Co., Ltd.

Product: m-PEG9-COOH 2576495-35-5
Price: US $0.00/g
Min. Order: 5g
Purity: >98.00%
Supply Ability: 5g
Release date: 2024-03-27

2576495-35-5, m-PEG9-COOHRelated Search:

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m-PEG9-COOH

2,5,8,11,14,17,20,23,26-Nonaoxanonacosan-29-oic acid

4,7,10,13,16,19,22,25,28-Nonaoxanonacosanoic acid

mPEG8-CH2CH2COOH/4,7,10,13,16,19,22,25,28-Nonaoxanonacosanoic acid

3-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

2576495-35-5