ChemicalBook > CAS DataBase List > N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine

N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine

Product Name
N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine
CAS No.
93285-75-7
Chemical Name
N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine
Synonyms
Iaa-Biotin;IODOACETYL LC BIOTIN;Biotin-C6-iodoacetamide;N-IODOACETYL-N-BIOTINYLHEXYLENEDIAMINE;N-IODOACETYL-N'-BIOTINYLHEXYLENEDIAMINE;N-Iodoacetyl-N'-biotinyl-1,6-hexanediamine;N-BIOTINYL-N'-(IODOACETYL)-1,6-HEXANEDIAMINE;N-Biotinyl-Na€-(iodoacetyl)-1,6-hexanediamine;N-Iodoacetyl-N-biotinylhexylenediaMine(Iodoacetyl-LC-Biotin);(3aS,4S,6aR)-Hexahydro-N-[6-[(iodoacetyl)amino]hexyl]-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide
CBNumber
CB5664328
Molecular Formula
C18H31IN4O3S
Formula Weight
510.43
MOL File
93285-75-7.mol
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N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine Property

Boiling point:
793.7±60.0 °C(Predicted)
Density 
1.414±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
Sealed in dry,2-8°C
solubility 
≥51 mg/mL in DMSO with gentle warming; insoluble in EtOH; insoluble in H2O
form 
solid
pka
13.90±0.40(Predicted)
color 
White to off-white
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Safety

Hazard Codes 
Xi
HS Code 
2928009090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

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N-Bromosuccinimide Price

TRC
Product number
B396025
Product name
N-Biotinyl-N’-(iodoacetyl)-1,6-hexanediamine
Packaging
50mg
Price
$560
Updated
2021/12/16
ApexBio Technology
Product number
A8009
Product name
Iodoacetyl-LC-Biotin
Packaging
100mg
Price
$185
Updated
2021/12/16
BroadPharm
Product number
BP-22638
Product name
Iodoacetyl-LC-Biotin
Purity
97%
Packaging
100mg
Price
$280
Updated
2021/12/16
BroadPharm
Product number
BP-22638
Product name
Iodoacetyl-LC-Biotin
Purity
97%
Packaging
250mg
Price
$560
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0009003
Product name
N-IODOACETYL-N-BIOTINYLHEXYLENEDIAMINE
Purity
95.00%
Packaging
100MG
Price
$715.75
Updated
2021/12/16
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N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine Chemical Properties,Usage,Production

Description

iodoacetyll-LC-Biotin is a sulfhydryl-reactive biotinylation reagent that forms stable, irreversible thioether bonds when reacting with with sulfhydryls (-SH) group at alkaline pH. The hexylenediamine spacer arm gives this reagent the membrane-impermeability which enables intracellular labeling of biomolecules.

Uses

N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine can be a useful reagent for biotinylation of proteins and subsequent use in a protein microarray.

Uses

amine reactive biotinylation reagent

Biological Activity

iodoacetyl-lc-biotin (n-iodoacetyl-n-biotinylhexylenediamine), a sulfhydryl-reactive biotinylation agent, is a water-insoluble reagent that requires the dissolution of suitable solvents, including dimethyl sulfoxide (dmso) and dimethylformamide (dmf), prior to the addition into aqueous reactions. iodoacetyl-lc-biotin consists of a bicyclic biotin rings structure, a 1,6-diaminohexane spacer group attached to the valeric acid side chain of biotin and an iodoacetyl group at the end of the spacer providing sulfhydryl reactivity. the iodoacetyl group at the end of iodoacetyl-lc-biotin is able to react with sulfhydryl groups on proteins and other molecules forming a nonreversible bond. the long spacer arm of iodoacetyl-lc-biotin enables the modified molecule to better bind to the avidin or streptavidin probes.bioconjugate techniques , 2nd ed. by greg t.hermanson (pierce biotechnology, thermo fisher scientific, rockford, il). academic press (an imprint of elsevier): london, amsterdam, burlington, san diego . 2008. isbn 978-0-12-370501-3.

N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine Suppliers

Canada 1 China 33 India 2 Japan 1 United Kingdom 1 United States 15 Global 53
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
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View Lastest Price from N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Biotin-C6-iodoacetamide 93285-75-7
Price
US $0.00/mg
Min. Order
250mg
Purity
>95.00%
Supply Ability
250mg
Release date
2024-03-30

93285-75-7, N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMineRelated Search:

BIOTIN HPDP BIOTINAMIDOCAPROYL HYDRAZIDE 1-BiotinaMido-4-[4`-(MaleiMidoMethyl)cyclohexanecarboxaMido]butane(Biotin-BMCC) Succinimidyl 6-(biotinamido)hexanoate 2-Iodoacetamide 1,7-DIAMINOHEPTANE N,N'-DIMETHYL-1,8-OCTANEDIAMINE 1,8-Diaminooctane 2,2'-Thiobisethylamine 2-METHYLTETRAHYDROTHIOPHENE N,N'-DIACETYL-1,6-DIAMINOHEXANE 2-HEPTANETHIOL N,N'-DIETHYL-1,6-DIAMINOHEXANE 2-(butylthio)ethanamine N-acetyl-1,6-diaminohexane N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine N,N'-DIFORMYL-1,6-DIAMINOHEXANE 3-THIOPHENAMINE, TETRAHYDRO-

  • N-IODOACETYL-N'-BIOTINYLHEXYLENEDIAMINE
  • N-IODOACETYL-N-BIOTINYLHEXYLENEDIAMINE
  • N-BIOTINYL-N'-(IODOACETYL)-1,6-HEXANEDIAMINE
  • IODOACETYL LC BIOTIN
  • (3aS,4S,6aR)-Hexahydro-N-[6-[(iodoacetyl)amino]hexyl]-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide
  • N-Iodoacetyl-N'-biotinyl-1,6-hexanediamine
  • (3aS,4S,6aR)-Hexahydro-N-[6-[(2-iodoacetyl)aMino]hexyl]-2-oxo-1H-thieno[3,4-d]iMidazole-4-pentanaMide
  • 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-[6-[(iodoacetyl)aMino]hexyl]-2-oxo-, (3aS,4S,6aR)-
  • N-Biotinyl-Na€-(iodoacetyl)-1,6-hexanediamine
  • N-Iodoacetyl-N-biotinylhexylenediaMine(Iodoacetyl-LC-Biotin)
  • 1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-N-[6-[(2-iodoacetyl)amino]hexyl]-2-oxo-, (3aS,4S,6aR)-
  • Iaa-Biotin
  • N-(6-(2-Iodoacetamido)hexyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
  • Biotin-C6-iodoacetamide
  • 93285-75-7
  • C18H31IN4O3S
  • BiotinylationReagents
  • MTS & Sulfhydryl Active Reagents
  • Biotin Derivatives
  • Cross Linking Reagents
  • biotinyl