2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
- Product Name
- 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
- CAS No.
- 64118-84-9
- Chemical Name
- 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
- Synonyms
- 4-HYDROXY DICLOFENAC;4-OHD;4'-OHD;Hydroxydiclofenac;4-HYDROXY DICLOFEC;4'-HYDROXYDICLOFENAC;4'-hydroxydiclofenac;Diclofenac Impurity 15;DICLOFENAC, 4'-HYDROXY-;4'-HYDROXYDICLOFENAC STANDARD
- CBNumber
- CB5672615
- Molecular Formula
- C14H11Cl2NO3
- Formula Weight
- 312.15
- MOL File
- 64118-84-9.mol
2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Property
- Melting point:
- 178-185°C dec.
- Boiling point:
- 432.7±45.0 °C(Predicted)
- Density
- 1.520±0.06 g/cm3(Predicted)
- Flash point:
- 2℃
- storage temp.
- -20°C
- solubility
- Soluble in DMSO, ethanol or methanol
- pka
- 4.17±0.10(Predicted)
- BRN
- 4198042
- Stability:
- Light Sensitive
Safety
- Hazard Codes
- T,N,Xn,F
- Risk Statements
- 25-37/38-41-50/53-36-20/21/22-11
- Safety Statements
- 26-39-45-60-61-36/37-16
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- AG6542800
- HazardClass
- 6.1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H3661
- Product name
- 4′-Hydroxydiclofenac
- Purity
- ≥98% (HPLC)
- Packaging
- 1vial
- Price
- $1440
- Updated
- 2024/03/01
- Product number
- H-052
- Product name
- 4′-Hydroxydiclofenac solution
- Purity
- 100?μg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging
- 1mL
- Price
- $369
- Updated
- 2024/03/01
- Product number
- 32412
- Product name
- 4′-Hydroxydiclofenac
- Purity
- VETRANAL , analytical standard
- Packaging
- 10mg
- Price
- $888
- Updated
- 2024/03/01
- Product number
- J64095
- Product name
- 4'-Hydroxydiclofenac
- Packaging
- 5mg
- Price
- $540.65
- Updated
- 2024/03/01
- Product number
- 10008518
- Product name
- 4-hydroxy Diclofenac
- Purity
- ≥97%
- Packaging
- 1mg
- Price
- $117
- Updated
- 2024/03/01
2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Chemical Properties,Usage,Production
Description
4-hydroxy Diclofenac is a CYP2C9 metabolite of the NSAID diclofenac . By inhibiting COX and subsequently suppressing PGE2 synthesis, it demonstrates anti-inflammatory and analgesic properties.
Chemical Properties
Light Violet Solid
Uses
A metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor
Uses
A Cytochrome P450 2C9 (CYP2C9) metabolite of diclofenac
Uses
A metabolite of Diclofenac, a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor.
Definition
ChEBI: An monocarboxylic acid that is the 4'-hydroxylated metabolite of diclofenac.
General Description
4′-Hydroxydiclofenac is one of the metabolites of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used in human and veterinary medicine.
2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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