ChemicalBook > CAS DataBase List > 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID

Product Name
2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
CAS No.
64118-84-9
Chemical Name
2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
Synonyms
4-HYDROXY DICLOFENAC;4-OHD;4'-OHD;Hydroxydiclofenac;4-HYDROXY DICLOFEC;4'-HYDROXYDICLOFENAC;4'-hydroxydiclofenac;Diclofenac Impurity 15;DICLOFENAC, 4'-HYDROXY-;4'-HYDROXYDICLOFENAC STANDARD
CBNumber
CB5672615
Molecular Formula
C14H11Cl2NO3
Formula Weight
312.15
MOL File
64118-84-9.mol
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2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Property

Melting point:
178-185°C dec.
Boiling point:
432.7±45.0 °C(Predicted)
Density 
1.520±0.06 g/cm3(Predicted)
Flash point:
2℃
storage temp. 
-20°C
solubility 
Soluble in DMSO, ethanol or methanol
pka
4.17±0.10(Predicted)
BRN 
4198042
Stability:
Light Sensitive
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Safety

Hazard Codes 
T,N,Xn,F
Risk Statements 
25-37/38-41-50/53-36-20/21/22-11
Safety Statements 
26-39-45-60-61-36/37-16
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
AG6542800
HazardClass 
6.1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H3661
Product name
4′-Hydroxydiclofenac
Purity
≥98% (HPLC)
Packaging
1vial
Price
$1440
Updated
2024/03/01
Sigma-Aldrich
Product number
H-052
Product name
4′-Hydroxydiclofenac solution
Purity
100?μg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$369
Updated
2024/03/01
Sigma-Aldrich
Product number
32412
Product name
4′-Hydroxydiclofenac
Purity
VETRANAL , analytical standard
Packaging
10mg
Price
$888
Updated
2024/03/01
Alfa Aesar
Product number
J64095
Product name
4'-Hydroxydiclofenac
Packaging
5mg
Price
$540.65
Updated
2024/03/01
Cayman Chemical
Product number
10008518
Product name
4-hydroxy Diclofenac
Purity
≥97%
Packaging
1mg
Price
$117
Updated
2024/03/01
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2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Chemical Properties,Usage,Production

Description

4-hydroxy Diclofenac is a CYP2C9 metabolite of the NSAID diclofenac . By inhibiting COX and subsequently suppressing PGE2 synthesis, it demonstrates anti-inflammatory and analgesic properties.

Chemical Properties

Light Violet Solid

Uses

A metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor

Uses

A Cytochrome P450 2C9 (CYP2C9) metabolite of diclofenac

Uses

A metabolite of Diclofenac, a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor.

Definition

ChEBI: An monocarboxylic acid that is the 4'-hydroxylated metabolite of diclofenac.

General Description

4′-Hydroxydiclofenac is one of the metabolites of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used in human and veterinary medicine.

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Suppliers

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64118-84-9, 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACIDRelated Search:

2-(2,6-Dichloroanilino) benzaldehyde 2-[(2,6-dichlorophenyl)amino]benzoicacid Oxindole Diclofenac sodium 1-(2,6-Dichlorophenyl)indolin-2-one (2-(2,6-DICHLOROANILINO)PHENYL) METHANOL 2-(2-Bromo-6-chlorophenyl)amino)-phenylacetic acid sodium salt 95% Diclofenac Impurity 7 Diclofenac Impurity 16 2,6-DICHLORODIPHENYLAMINE 4-HYDROXY-2'-METHYLDIPHENYLAMINE Phenylacetic acid 1-(2,6-Dichlorophenyl)-2-indolinone 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID 4-Amino-3-chlorophenol hydrochloride 2-ANILINOPHENYLACETIC ACID (2-(2,6-Dichloro-4-hydroxyanilino)-5-hydroxyphenyl)acetic acid 4Hydroxy Diclofenac-D4 (Major)

  • (o-(2,6-dichloro-4-hydroxyanilino)phenyl)-aceticaci
  • (o-(2,6-dichloro-4-hydroxyanilino)phenyl)aceticacid
  • DICLOFENAC, 4'-HYDROXY-
  • 4'-OHD
  • 4-OHD
  • 4-HYDROXY DICLOFENAC
  • 4'-HYDROXYDICLOFENAC
  • 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
  • 4'-HYDROXYDICLOFENAC STANDARD
  • [2-(2,6-Dichloro-4-hydroxyanilino)phenyl]acetic acid
  • 2-(2,6-Dichloro-4-hydroxyanilino)benzeneacetic acid
  • Benzeneacetic acid, 2-[(2,6-dichloro-4-hydroxyphenyl)aMino]-
  • Hydroxydiclofenac
  • 4′-Hydroxydiclofenac solution
  • 4'-Hydroxydiclofenac VETRANAL(TM), analytical standard
  • Diclofenac Impurity 15
  • 2-(2-((2,6-dichloro-4-hydroxyphenyl)amino)phenyl)acetic acid
  • 4-HYDROXY DICLOFEC
  • 4'-hydroxydiclofenac
  • 64118-84-9
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