ChemicalBook > CAS DataBase List > 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID

Product Name
2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
CAS No.
64118-84-9
Chemical Name
2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
Synonyms
4-HYDROXY DICLOFENAC;4-OHD;4'-OHD;Hydroxydiclofenac;4-HYDROXY DICLOFEC;4'-HYDROXYDICLOFENAC;4'-hydroxydiclofenac;Diclofenac Impurity 15;DICLOFENAC, 4'-HYDROXY-;4'-HYDROXYDICLOFENAC STANDARD
CBNumber
CB5672615
Molecular Formula
C14H11Cl2NO3
Formula Weight
312.15
MOL File
64118-84-9.mol
More
Less

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Property

Melting point:
178-185°C dec.
Boiling point:
432.7±45.0 °C(Predicted)
Density 
1.520±0.06 g/cm3(Predicted)
Flash point:
2℃
storage temp. 
-20°C
solubility 
Soluble in DMSO, ethanol or methanol
pka
4.17±0.10(Predicted)
form 
Solid
color 
White to off-white
BRN 
4198042
Stability:
Light Sensitive
More
Less

Safety

Hazard Codes 
T,N,Xn,F
Risk Statements 
25-37/38-41-50/53-36-20/21/22-11
Safety Statements 
26-39-45-60-61-36/37-16
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
AG6542800
HazardClass 
6.1
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H3661
Product name
4′-Hydroxydiclofenac
Purity
≥98% (HPLC)
Packaging
1vial
Price
$1440
Updated
2024/03/01
Sigma-Aldrich
Product number
H-052
Product name
4′-Hydroxydiclofenac solution
Purity
100?μg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$369
Updated
2024/03/01
Sigma-Aldrich
Product number
32412
Product name
4′-Hydroxydiclofenac
Purity
VETRANAL , analytical standard
Packaging
10mg
Price
$888
Updated
2024/03/01
Alfa Aesar
Product number
J64095
Product name
4'-Hydroxydiclofenac
Packaging
5mg
Price
$540.65
Updated
2024/03/01
Cayman Chemical
Product number
10008518
Product name
4-hydroxy Diclofenac
Purity
≥97%
Packaging
1mg
Price
$117
Updated
2024/03/01
More
Less

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Chemical Properties,Usage,Production

Description

4-hydroxy Diclofenac is a CYP2C9 metabolite of the NSAID diclofenac . By inhibiting COX and subsequently suppressing PGE2 synthesis, it demonstrates anti-inflammatory and analgesic properties.

Chemical Properties

Light Violet Solid

Uses

A metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor

Uses

A Cytochrome P450 2C9 (CYP2C9) metabolite of diclofenac

Uses

A metabolite of Diclofenac, a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor.

Definition

ChEBI: An monocarboxylic acid that is the 4'-hydroxylated metabolite of diclofenac.

General Description

4′-Hydroxydiclofenac is one of the metabolites of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used in human and veterinary medicine.

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81960175
Fax
+1-541-2553641
Email
min.he@cato-chem.com
Country
China
ProdList
1955
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18070
Advantage
56
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
Advantage
50

64118-84-9, 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACIDRelated Search:


  • (o-(2,6-dichloro-4-hydroxyanilino)phenyl)-aceticaci
  • (o-(2,6-dichloro-4-hydroxyanilino)phenyl)aceticacid
  • DICLOFENAC, 4'-HYDROXY-
  • 4'-OHD
  • 4-OHD
  • 4-HYDROXY DICLOFENAC
  • 4'-HYDROXYDICLOFENAC
  • 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
  • 4'-HYDROXYDICLOFENAC STANDARD
  • [2-(2,6-Dichloro-4-hydroxyanilino)phenyl]acetic acid
  • 2-(2,6-Dichloro-4-hydroxyanilino)benzeneacetic acid
  • Benzeneacetic acid, 2-[(2,6-dichloro-4-hydroxyphenyl)aMino]-
  • Hydroxydiclofenac
  • 4′-Hydroxydiclofenac solution
  • 4'-Hydroxydiclofenac VETRANAL(TM), analytical standard
  • Diclofenac Impurity 15
  • 2-(2-((2,6-dichloro-4-hydroxyphenyl)amino)phenyl)acetic acid
  • 4-HYDROXY DICLOFEC
  • 4'-hydroxydiclofenac
  • 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
  • 64118-84-9
  • HU - HZ
  • Analytical Standards
  • Analytical Chromatography Product Catalog
  • Alphabetic
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals