2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID

Product Name: 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
CAS No.: 64118-84-9
Chemical Name: 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
Synonyms: 4-HYDROXY DICLOFENAC;4-OHD;4'-OHD;Hydroxydiclofenac;4-HYDROXY DICLOFEC;4'-HYDROXYDICLOFENAC;4'-hydroxydiclofenac;Diclofenac Impurity 15;DICLOFENAC, 4'-HYDROXY-;4'-HYDROXYDICLOFENAC STANDARD
CBNumber: CB5672615
Molecular Formula: C14H11Cl2NO3
Formula Weight: 312.15
MOL File: 64118-84-9.mol

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2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Property

Melting point:: 178-185°C dec.
Boiling point:: 432.7±45.0 °C(Predicted)
Density: 1.520±0.06 g/cm3(Predicted)
Flash point:: 2℃
storage temp.: -20°C
solubility: Soluble in DMSO, ethanol or methanol
pka: 4.17±0.10(Predicted)
form: Solid
color: White to off-white
BRN: 4198042
Stability:: Light Sensitive

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Safety

Hazard Codes: T,N,Xn,F
Risk Statements: 25-37/38-41-50/53-36-20/21/22-11
Safety Statements: 26-39-45-60-61-36/37-16
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: AG6542800
HazardClass: 6.1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H3661
Product name: 4′-Hydroxydiclofenac
Purity: ≥98% (HPLC)
Packaging: 1vial
Price: $1440
Updated: 2024/03/01

Sigma-Aldrich

Product number: H-052
Product name: 4′-Hydroxydiclofenac solution
Purity: 100?μg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1mL
Price: $369
Updated: 2024/03/01

Sigma-Aldrich

Product number: 32412
Product name: 4′-Hydroxydiclofenac
Purity: VETRANAL , analytical standard
Packaging: 10mg
Price: $888
Updated: 2024/03/01

Alfa Aesar

Product number: J64095
Product name: 4'-Hydroxydiclofenac
Packaging: 5mg
Price: $540.65
Updated: 2024/03/01

Cayman Chemical

Product number: 10008518
Product name: 4-hydroxy Diclofenac
Purity: ≥97%
Packaging: 1mg
Price: $117
Updated: 2024/03/01

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2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Chemical Properties,Usage,Production

Description

4-hydroxy Diclofenac is a CYP2C9 metabolite of the NSAID diclofenac . By inhibiting COX and subsequently suppressing PGE₂ synthesis, it demonstrates anti-inflammatory and analgesic properties.

Chemical Properties

Light Violet Solid

Uses

A metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor

Uses

A Cytochrome P450 2C9 (CYP2C9) metabolite of diclofenac

Uses

A metabolite of Diclofenac, a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor.

Definition

ChEBI: An monocarboxylic acid that is the 4'-hydroxylated metabolite of diclofenac.

General Description

4′-Hydroxydiclofenac is one of the metabolites of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used in human and veterinary medicine.

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Suppliers

Canada 3 China 67 Germany 1 India 7 Switzerland 1 United Kingdom 3 United States 16 Global 98

Toronto Research Chemicals

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64118-84-9, 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACIDRelated Search:

2-(2,6-Dichloroanilino) benzaldehyde 2-[(2,6-dichlorophenyl)amino]benzoicacid Oxindole Diclofenac sodium 1-(2,6-Dichlorophenyl)indolin-2-one (2-(2,6-DICHLOROANILINO)PHENYL) METHANOL 2-(2-Bromo-6-chlorophenyl)amino)-phenylacetic acid sodium salt 95% Diclofenac Impurity 7 Diclofenac Impurity 16 2,6-DICHLORODIPHENYLAMINE 4-HYDROXY-2'-METHYLDIPHENYLAMINE Phenylacetic acid 1-(2,6-Dichlorophenyl)-2-indolinone 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID 4-Amino-3-chlorophenol hydrochloride 2-ANILINOPHENYLACETIC ACID (2-(2,6-Dichloro-4-hydroxyanilino)-5-hydroxyphenyl)acetic acid 4Hydroxy Diclofenac-D4 (Major)

(o-(2,6-dichloro-4-hydroxyanilino)phenyl)-aceticaci

(o-(2,6-dichloro-4-hydroxyanilino)phenyl)aceticacid

DICLOFENAC, 4'-HYDROXY-

4'-OHD

4-OHD

4-HYDROXY DICLOFENAC

4'-HYDROXYDICLOFENAC

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID

4'-HYDROXYDICLOFENAC STANDARD

[2-(2,6-Dichloro-4-hydroxyanilino)phenyl]acetic acid

2-(2,6-Dichloro-4-hydroxyanilino)benzeneacetic acid

Benzeneacetic acid, 2-[(2,6-dichloro-4-hydroxyphenyl)aMino]-

Hydroxydiclofenac

4′-Hydroxydiclofenac solution

4'-Hydroxydiclofenac VETRANAL(TM), analytical standard

Diclofenac Impurity 15

2-(2-((2,6-dichloro-4-hydroxyphenyl)amino)phenyl)acetic acid

4-HYDROXY DICLOFEC

4'-hydroxydiclofenac

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID

64118-84-9

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