3-Bromo-2-hydroxy-5-nitropyridine
- Product Name
- 3-Bromo-2-hydroxy-5-nitropyridine
- CAS No.
- 15862-33-6
- Chemical Name
- 3-Bromo-2-hydroxy-5-nitropyridine
- Synonyms
- 3-Bromo-5-nitro-2-pyridone;3-BROMO-5-NITRO-2-PYRIDINOL;3-Bromo-5-nitropyridin-2-ol;Pyridin-2-ol, 3-bromo-5-nitro-;3-BROMO-5-NITRO-2(1H)-PYRIDINONE;3-BROMO-2-HYDROXY-5-NITROPYRIDINE;3-Bromo-5-nitro-2-hydroxypyridine;2-Hydroxy-5-nitro-3-bromopyridine;2(1H)-Pyridinone, 3-bromo-5-nitro-;3-BroMo-2-hydroxyY-5-nitropyridine
- CBNumber
- CB5678682
- Molecular Formula
- C5H3BrN2O3
- Formula Weight
- 218.99
- MOL File
- 15862-33-6.mol
3-Bromo-2-hydroxy-5-nitropyridine Property
- Melting point:
- 213-218℃
- Boiling point:
- 300.9±42.0 °C(Predicted)
- Density
- 1.98±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 6.58±0.10(Predicted)
- form
- Solid
- color
- White to Light yellow
- InChI
- InChI=1S/C5H3BrN2O3/c6-4-1-3(8(10)11)2-7-5(4)9/h1-2H,(H,7,9)
- InChIKey
- KWSOHRDMTWDAOI-UHFFFAOYSA-N
- SMILES
- C1(=O)NC=C([N+]([O-])=O)C=C1Br
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 22-37/38-41
- Safety Statements
- 26-39
- RIDADR
- UN 2811 6.1 / PGIII
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- IRRITANT, KEEP COLD
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 750557
- Product name
- 3-Bromo-2-hydroxy-5-nitropyridine
- Purity
- 95%
- Packaging
- 1g
- Price
- $29.1
- Updated
- 2023/01/07
- Product number
- 750557
- Product name
- 3-Bromo-2-hydroxy-5-nitropyridine
- Purity
- 95%
- Packaging
- 5g
- Price
- $112
- Updated
- 2023/01/07
- Product number
- B4672
- Product name
- 3-Bromo-2-hydroxy-5-nitropyridine
- Purity
- >97.0%(GC)(T)
- Packaging
- 5g
- Price
- $57
- Updated
- 2025/07/31
- Product number
- B4672
- Product name
- 3-Bromo-2-hydroxy-5-nitropyridine
- Purity
- >97.0%(GC)(T)
- Packaging
- 25g
- Price
- $227
- Updated
- 2025/07/31
- Product number
- B686278
- Product name
- 3-Bromo-5-nitro-2(1H)-pyridinone
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
3-Bromo-2-hydroxy-5-nitropyridine Chemical Properties,Usage,Production
Uses
3-Bromo-2-hydroxy-5-nitropyridine is used widely in fields such as medicine, agricultural chemicals and organic syntheses.
Synthesis
5418-51-9
15862-33-6
General procedure for the synthesis of 3-bromo-2-hydroxy-5-nitropyridine from 2-hydroxy-5-nitropyridine: Step 1: A mixture of 2-hydroxy-5-nitropyridine (50 g, 0.358 mol) and water (7 L) was heated to 40 °C, followed by the slow dropwise addition of bromine (21 mL, 0.393 mol) over 20 min. The reaction mixture was cooled to 10 °C after continuous stirring at 40 °C for 2.5 hours. The crude product was separated by filtration and the solid was washed with water and dried under vacuum to give 70 g of 3-bromo-2-hydroxy-5-nitropyridine as a solid (90% yield). The product had a melting point of 212-214 °C (accompanied by decomposition); 1H NMR (CD3OD) δ 8.66 (d, J = 2.9 Hz, 1H), 8.64 (d, J = 2.9 Hz, 1H).
References
[1] Patent: WO2015/92011, 2015, A1. Location in patent: Page/Page column 31
[2] Patent: WO2009/21696, 2009, A1. Location in patent: Page/Page column 42
[3] Patent: US2006/79522, 2006, A1. Location in patent: Page/Page column 8; 12-13
[4] Patent: US2006/79523, 2006, A1. Location in patent: Page/Page column 9; 13
[5] Patent: US2006/79524, 2006, A1. Location in patent: Page/Page column 9; 13
3-Bromo-2-hydroxy-5-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
3-Bromo-2-hydroxy-5-nitropyridine Suppliers
- Tel
- 0519-89891966 13906113265
- 986329407@qq.com
- Country
- China
- ProdList
- 51
- Advantage
- 58
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
- Advantage
- 62
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 0531-88811783
- Fax
- +86 (531) 55696010 QQ 1762738062
- sales@trio-pharmatech.com
- Country
- China
- ProdList
- 1856
- Advantage
- 62
View Lastest Price from 3-Bromo-2-hydroxy-5-nitropyridine manufacturers
- Product
- 3-Bromo-2-hydroxy-5-nitropyridine 15862-33-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-29
- Product
- 3-Bromo-2-hydroxy-5-nitropyridine 15862-33-6
- Price
- US $6.00-0.20/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-03
- Product
- 3-Bromo-2-hydroxy-5-nitropyridine 15862-33-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-09-24