ChemicalBook > CAS DataBase List > 1,3-Bis(4-aMinophenoxy)benzene

1,3-Bis(4-aMinophenoxy)benzene

Product Name: 1,3-Bis(4-aMinophenoxy)benzene
CAS No.: 2479-46-1
Chemical Name: 1,3-Bis(4-aMinophenoxy)benzene
Synonyms: TPE-R;1,3,4-APB;7FDA;4,4'-(m-Phenyle;RESORCINOLDIANILINE;4,4'-(1,3-Phenylened;resorcinoloxydianiline;4,4-(1,3-PHENEDIOXY)DIANILINE;1,3-BIS(4-AMINOPHENOXY)BENZENE;1,3-Bis(4'-Amino-phenoxyl)benz
CBNumber: CB5687981
Molecular Formula: C18H16N2O2
Formula Weight: 292.33
MOL File: 2479-46-1.mol

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1,3-Bis(4-aMinophenoxy)benzene Property

Melting point:: 115-118 °C(lit.)
Boiling point:: 434.27°C (rough estimate)
Density: 1.1925 (rough estimate)
refractive index: 1.5700 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: very faint turbidity in Acetonitrile
form: powder to crystal
pka: 5.06±0.10(Predicted)
color: White to Brown
InChI: InChI=1S/C18H16N2O2/c19-13-4-8-15(9-5-13)21-17-2-1-3-18(12-17)22-16-10-6-14(20)7-11-16/h1-12H,19-20H2
InChIKey: WUPRYUDHUFLKFL-UHFFFAOYSA-N
SMILES: C1(OC2=CC=C(N)C=C2)=CC=CC(OC2=CC=C(N)C=C2)=C1
CAS DataBase Reference: 2479-46-1(CAS DataBase Reference)
EPA Substance Registry System: Benzenamine, 4,4'-[1,3-phenylenebis(oxy)]bis- (2479-46-1)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: BY8236000
HS Code: 29222990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 476323
Product name: 4,4′-(1,3-Phenylenedioxy)dianiline
Purity: 98%
Packaging: 100g
Price: $407
Updated: 2025/07/31

TCI Chemical

Product number: B1680
Product name: 1,3-Bis(4-aminophenoxy)benzene
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $89
Updated: 2025/07/31

TRC

Product number: B405505
Product name: 1,3-Bis(4-aminophenoxy)benzene
Packaging: 500mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB62666
Product name: 1,3-Bis(4-aminophenoxy)benzene
Packaging: 50g
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB62666
Product name: 1,3-Bis(4-aminophenoxy)benzene
Packaging: 100g
Price: $80
Updated: 2021/12/16

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1,3-Bis(4-aMinophenoxy)benzene Chemical Properties,Usage,Production

Chemical Properties

Light yellow powder

Uses

1,3-Bis(4'-aminophenoxyl)benzene be used for the preparation of a polyimide material.

Application

1,3-Bis(4-aMinophenoxy)benzene (TPE-R) is a phenyl ether derivative with two anilines in the terminal closure. It has the following applications:
(1) TPE-R with BPDA and BPDA can be used to prepare a series of polyimide oligomer (Oligo-PI) resins with controlled molecular weights through polymerisation reactions. Oligo-PI resins have an asymmetric and amorphous structure, which allows for better processing of composite materials.
(2) TPE-R copolymerised with other monomers (e.g. PEG) for the manufacture of fuel cell membranes with high ionic conductivity (210 mS/cm) and sufficient thermal stability (up to 140 °C).
(3) Polyimide composites prepared from TPE-R and titanate nanotubes can be used for electromagnetic shielding at microwave frequencies.
(4) TPE-R as an aromatic ligand can be crystallised with a variety of transition metals to form 0D, 1D and 2D coordination metal polymers, which can be used for sensing nitroaromatic compounds.
(5) TPE-R reacts with polydimethylsiloxanes with varying degrees of chloromethyl side functionalisation to form sec-amides and undergo cross-linking to form two networks, a siloxane-organic network and a silica network.

Synthesis

13118-94-0

2479-46-1

GENERAL METHOD: A mixture of 1,3-bis(4-nitrophenoxy)benzene (1.8 g, 5.1 mmol) with 10% Pd/C (0.2 g) in methanol (70 mL) was subjected to a hydrogen atmosphere and stirred at room temperature overnight. Upon completion of the reaction, the reaction mixture was treated by diafiltration, followed by addition of water (50 mL) to the filtrate and extraction with dichloromethane three times (3 x 50 mL). The organic layers were combined, washed with brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by column chromatography to afford the target product 1,3-bis(4'-aminophenoxy)benzene as a brown solid in 56.0%, 55.0% and 69.0% yields.

Toxicity evaluation

orl-mus LD50:1240 mg/kg; orl-rat LD50:1378 mg/kg; ora-rat LD50:690 mg/kg [pubchem].

References

[1] Heteroatom Chemistry, 2013, vol. 24, # 1, p. 9 - 17
[2] Dyes and Pigments, 2015, vol. 121, p. 170 - 177
[3] Chinese Chemical Letters, 2013, vol. 24, # 10, p. 869 - 872

1,3-Bis(4-aMinophenoxy)benzene Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1,3-Bis(4-aMinophenoxy)benzene manufacturers

CHINATECH(TIANJIN) CHEMICAL CO.,LTD.

Product: 1,3-Bis(4-aminophenoxy)benzene (TPE-R) 2479-46-1
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: ≥99.5%
Supply Ability: 30MT
Release date: 2025-10-27

HANGZHOU HAILAN CHEMICAL CO.,LTD.

Product: 1,3-Bis(4-aMinophenoxy)benzene 2479-46-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 20tons
Release date: 2025-09-05

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 1,3-Bis(4-aMinophenoxy)benzene 2479-46-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-24

2479-46-1, 1,3-Bis(4-aMinophenoxy)benzeneRelated Search:

Allylbenzene Ethylbenzene 4-Aminophenylacetic acid Methyl anthranilate Sulfanilamide Aniline p-Anisidine Sulfanilic acid Benzocaine 4-Aminobenzoic acid Benzene 1,3-DIPHENOXYBENZENE 3-PHENOXYPHENOL 4-Phenoxyaniline Anthranilic acid 4,4'-(1,4-Phenylenedioxy)dianiline,4,4'-(P-PHENYLENEDIOXY)DIANILINE 1,3-Bis(3-aminophenoxy)benzene 3,5-BIS(4-NITROPHENOXY)BENZOIC ACID

4,4-(1,3-PHENEDIOXY)DIANILINE

Benzenamine, 4,4'-[1,3-phenylenebis(oxy)]bis-

4,4'-[1,3-phenylenebis(oxy)]dianiline

4,4'-(m-Phenylenebisoxy)bis(aniline)

4,4'-(m-Phenylenebisoxy)dianiline

4,4'-(m-Phenylenedioxy)bisaniline

RESORCINOL BIS(4-AMINOPHENYL) ETHER

TPE-R

1,3-BIS(4-AMINOPHENOXY)BENZENE

1,3,4-APB

1,3-Bis(4-aminophenoxy)benzene (TPE-R).

1,3-Bis(4'-Amino-phenoxyl)benz

RESORCINOLDIANILINE

4,4'-(M-PHENYLENEDIOXY)DIANILINE

4,4'-(m-Phenyle

1,3'-Bis(4-aminophenoxyl)benzene (1,3,4-APB,TPE-R)

1,3-Bis(4-aminophenoxy)benzene ,99%

4,4'-(1,3-Phenylened

1,3-Bis(4-AMinophenoxy) Benzene (TPE-R) 4,4'-(1,3-Phenylenedioxy) Dianiline

4,4'-(1,3-Phenylenedioxy)dianiline 98%

1,3'-Bis(4-aminophenoxyl)benzene (TPE-R)

1,3-phenylene-di-4-aminophenylether

4,4’-(1,3-phenylenebis(oxy))bis-benzenamin

p,p’-(m-phenylenedioxy)di-anilin

resorcinoloxydianiline

4,4'-[1,3-Phenylenebis(oxy)]bisaniline

1,3-Bis(4-aminophenoxy)benzene &gt

7FDA

1,3-Bis(4-aminophenoxy)benzene(TPE-R) CAS

1,3'-Bis(4-aminophenoxyl)benzene

1,3-bis(4'-Aminophenoxyl)benzene

4,4'-(1,3-phenylenedioxy)dianiline

1,3-bis(4'-aminophenoxy)benzene

4,4'-(1,3-phenylenebis(oxy))dianiline

1,3-Bis( 4-aminophenoxy)benzene (TPE-R/1,3,4-APB)

1,3-bis(4′-Aminophenoxyl)benzene, CAS 2479-46-1

4,4'-(1,3-Phenylenedioxy)dianiline

1,3-Bis(4'-aminophenoxyl)benzene

2479-46-1

2427-46-1

C6H4OC6H4NH22

C18H16N2O2

C18H16O2N2

Diphenyl Ethers (for High-Performance Polymer Research)

Reagent for High-Performance Polymer Research

Amine Monomers

Monomers

Primary Amines

Electronic Chemicals

Miscellaneous

Diphenyl Ethers (for High-Performance Polymer Research)

Functional Materials

Reagent for High-Performance Polymer Research

2479-46-1