Methyl 2,5-dibromobenzoate
- Product Name
- Methyl 2,5-dibromobenzoate
- CAS No.
- 57381-43-8
- Chemical Name
- Methyl 2,5-dibromobenzoate
- Synonyms
- METHYL 2,5-DIBROMOBENZOATE;Methyl2,5-Dibromobenzoate>Methyl 2,5-dibromobenzoate-98%;2,5-DIBROMOBENZOIC ACID METHYL ESTER;Benzoic acid, 2,5-dibromo-, methyl ester;2,5-DIBROMOBENZOIC ACID METHYL ESTER 98+%
- CBNumber
- CB5689697
- Molecular Formula
- C8H6Br2O2
- Formula Weight
- 293.94
- MOL File
- 57381-43-8.mol
Methyl 2,5-dibromobenzoate Property
- Melting point:
- 48-51 °C (lit.)
- Boiling point:
- 291.3±20.0 °C(Predicted)
- Density
- 1.840±0.06 g/cm3(Predicted)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- color
- White to Orange to Green
- Water Solubility
- Slightly soluble in water.
- CAS DataBase Reference
- 57381-43-8(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 532894
- Product name
- Methyl 2,5-dibromobenzoate
- Purity
- 99%
- Packaging
- 25g
- Price
- $188
- Updated
- 2023/01/07
- Product number
- D2673
- Product name
- Methyl 2,5-Dibromobenzoate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $45
- Updated
- 2025/07/31
- Product number
- D2673
- Product name
- Methyl 2,5-Dibromobenzoate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $141
- Updated
- 2025/07/31
- Product number
- M301218
- Product name
- Methyl 2,5-dibromobenzoate
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 2623-9-07
- Product name
- Methyl 2,5-dibromobenzoate
- Purity
- 98%
- Packaging
- 25g
- Price
- $103
- Updated
- 2021/12/16
Methyl 2,5-dibromobenzoate Chemical Properties,Usage,Production
General Description
Methyl 2,5-dibromobenzoate, an aromatic ester, can be prepared from 2,5-dibromobenzoic acid via esterification with methanol. It undergoes Ni(0)-catalyzed polymerization to form soluble polyphenylenes.
Synthesis
67-56-1
610-71-9
57381-43-8
Step 1: A methanol (2L) solution of 2,5-dibromobenzoic acid (250 g, 0.90 mol) and concentrated sulfuric acid (18.4 g, 0.19 mol) were added to a 2L round bottom flask. The reaction mixture was heated to reflux overnight and subsequently cooled to room temperature. The resulting precipitate was collected by filtration, washed with cold methanol and dried under vacuum to give 203.6 g of methyl 2,5-dibromobenzoate as a yellow solid. Step 2: To another 2L round-bottomed flask was added a solution of methyl 2,5-dibromobenzoate (198.2 g, 0.68 mol) in anhydrous DMF (1L). Copper cyanide (122 g, 1.36 mol) and sodium iodide (22.8 g, 0.15 mol) were subsequently added. The mixture was stirred at 130 °C overnight under nitrogen protection. Upon completion of the reaction, extraction was carried out with ethyl acetate (500 mL x 3), the organic layer was washed with water (500 mL), and finally purified by silica gel column chromatography (petroleum ether/ethyl acetate = 5/1) to afford 95.2 g of methyl 2,5-dicyanobenzoate as a brown solid in 75.1% yield.
References
[1] Tetrahedron, 2016, vol. 72, # 24, p. 3454 - 3467
[2] Asian Journal of Chemistry, 2014, vol. 26, # 19, p. 6655 - 6657
Methyl 2,5-dibromobenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 2,5-dibromobenzoate manufacturers
- Product
- Methyl 2,5-dibromobenzoate 57381-43-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-11