Tris(2-methyl-1-aziridinyl)phosphine oxide Property

Melting point:

25°C

Boiling point:

90-92 °C (0.15-0.3 mmHg)

Density 

1.0790

form 

liquid

pka

3.80±0.40(Predicted)

Odor

amine odor

NIST Chemistry Reference

Tris(1-(2-methyl)aziridinyl)phosphine oxide(57-39-6)

IARC

3 (Vol. 9, Sup 7) 1987

EPA Substance Registry System

Metapa (57-39-6)

Safety

RIDADR 

2810

HazardClass 

6.1(b)

PackingGroup 

III

Toxicity

LD50 in male, female rats (mg/kg): 136, 213 orally (Gaines)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H310Fatal in contact with skin

Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P350IF ON SKIN: Gently wash with plenty of soap and water.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

Tris(2-methyl-1-aziridinyl)phosphine oxide Chemical Properties,Usage,Production

Chemical Properties

Amber liquid; amine odor. Miscible with water and organic solvents.

Uses

Metepa is a chemosterilant.

Uses

Chemosterilant; in creaseproofing and flameproofing textiles.

Definition

ChEBI: Tris(2-methyl-1-aziridinyl)phosphine oxide is a phosphoramide.

Hazard

Toxic by ingestion and skin absorption, strong irritant to skin.

Safety Profile

Poison by ingestion, skin contact, intraperitoneal, and subcutaneous routes. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental carcinogenic data. Animal experiments suggest cholinesterase inlubition, possibly due to metabolic products of this material in the body. When heated to decomposition it emits very toxic fumes of NOx and POx.