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Tris(2-methyl-1-aziridinyl)phosphine oxide

Product Name
Tris(2-methyl-1-aziridinyl)phosphine oxide
CAS No.
57-39-6
Chemical Name
Tris(2-methyl-1-aziridinyl)phosphine oxide
Synonyms
mapo;c3172;metepa;MAPO(R);ent50,003;metapoxide;MAPO HIIA;Methapoxide;methaphoxide;Methyl aphoxide
CBNumber
CB5693380
Molecular Formula
C9H18N3OP
Formula Weight
215.23
MOL File
57-39-6.mol
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Tris(2-methyl-1-aziridinyl)phosphine oxide Property

Melting point:
25°C
Boiling point:
90-92 °C (0.15-0.3 mmHg)
Density 
1.0790
form 
liquid
pka
3.80±0.40(Predicted)
Odor
amine odor
InChI
InChI=1S/C9H18N3P/c1-7-4-10(7)13(11-5-8(11)2)12-6-9(12)3/h7-9H,4-6H2,1-3H3
InChIKey
DKKKIFBZPVPZMU-UHFFFAOYSA-N
SMILES
P(N1CC1C)(N1CC1C)N1CC1C
NIST Chemistry Reference
Tris(1-(2-methyl)aziridinyl)phosphine oxide(57-39-6)
IARC
3 (Vol. 9, Sup 7) 1987
EPA Substance Registry System
Metapa (57-39-6)
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Safety

RIDADR 
2810
HazardClass 
6.1(b)
PackingGroup 
III
Toxicity
LD50 in male, female rats (mg/kg): 136, 213 orally (Gaines)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H310Fatal in contact with skin

Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P350IF ON SKIN: Gently wash with plenty of soap and water.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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Tris(2-methyl-1-aziridinyl)phosphine oxide Chemical Properties,Usage,Production

Chemical Properties

Amber liquid; amine odor. Miscible with water and organic solvents.

Uses

Metepa is a chemosterilant.

Uses

Chemosterilant; in creaseproofing and flameproofing textiles.

Definition

ChEBI: Tris(2-methyl-1-aziridinyl)phosphine oxide is a phosphoramide.

Hazard

Toxic by ingestion and skin absorption, strong irritant to skin.

Safety Profile

Poison by ingestion, skin contact, intraperitoneal, and subcutaneous routes. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental carcinogenic data. Animal experiments suggest cholinesterase inlubition, possibly due to metabolic products of this material in the body. When heated to decomposition it emits very toxic fumes of NOx and POx.

Tris(2-methyl-1-aziridinyl)phosphine oxide Preparation Products And Raw materials

Raw materials

Preparation Products

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Tris(2-methyl-1-aziridinyl)phosphine oxide Suppliers

Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
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58
Alfa Chemistry
Tel
--
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Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Wonda Science
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--
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Email
wonda@wondascience.com
Country
United States
ProdList
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50
MP Biomedicals, Inc.
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Country
United States
ProdList
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Amfinecom Inc.
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sales@amfinecom.com
Country
United States
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Chemstock Inc.
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mail@chemstock.com
Country
United States
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3B Scientific Corporation
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sales@3bsc.com
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United States
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Orion Chem Pvt. Ltd.
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Riedel-de Haen AG
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United States
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Aceto Corporation
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Pfaltz & Bauer, Inc.
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George Uhe Co., Inc.
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Country
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