ChemicalBook > CAS DataBase List > Isopropyl chloroformate

Isopropyl chloroformate

Product Name
Isopropyl chloroformate
CAS No.
108-23-6
Chemical Name
Isopropyl chloroformate
Synonyms
isopropyl carbonochloridate;IPCF;ISOPROPYL CHLOROCARBONATE;ISOPROPYL CHLOROMATE;Isopropyl chloroform;1-PROPYLCHLOROFORMATE;2-Methylchloroformate;Tenofovir Impurity 95;Isopropylchlorcarbonat;sopropyl chloroformate
CBNumber
CB5702693
Molecular Formula
C4H7ClO2
Formula Weight
122.55
MOL File
108-23-6.mol
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Isopropyl chloroformate Property

Boiling point:
105 °C
Density 
0.892 g/mL at 25 °C
vapor pressure 
27.998hPa at 20℃
refractive index 
n20/D 1.485(lit.)
Flash point:
43 °F
storage temp. 
2-8°C
solubility 
Chloroform (Sparingly), Dichloromethane (Soluble), Ethyl Acetate (Slightly), Tol
form 
liquid
BRN 
506416
Stability:
Moisture Sensitive
InChIKey
IVRIRQXJSNCSPQ-UHFFFAOYSA-N
CAS DataBase Reference
108-23-6(CAS DataBase Reference)
EPA Substance Registry System
Isopropyl chloroformate (108-23-6)
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Safety

Hazard Codes 
F,C,T+
Risk Statements 
11-34-48/20-63-65-67-43-26
Safety Statements 
26-36/37/39-45-62-28-16
RIDADR 
UN 3286 3/PG 2
WGK Germany 
2
RTECS 
LQ6475000
F 
10-19
HazardClass 
6.1(a)
PackingGroup 
I
HS Code 
29159000
Hazardous Substances Data
108-23-6(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H304May be fatal if swallowed and enters airways

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H330Fatal if inhaled

H336May cause drowsiness or dizziness

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
335908
Product name
Isopropyl chloroformate solution
Purity
1.0M in toluene
Packaging
100ml
Price
$101
Updated
2024/03/01
Sigma-Aldrich
Product number
335908
Product name
Isopropyl chloroformate solution
Purity
1.0M in toluene
Packaging
800ml
Price
$201
Updated
2024/03/01
TRC
Product number
I824330
Product name
IsopropylChloroformate,30%inToluene
Packaging
10g
Price
$80
Updated
2021/12/16
TRC
Product number
I824330
Product name
IsopropylChloroformate,30%inToluene
Packaging
100g
Price
$225
Updated
2021/12/16
Matrix Scientific
Product number
139325
Product name
Isopropyl chloroformate
Purity
95%+
Packaging
5g
Price
$323
Updated
2021/12/16
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Isopropyl chloroformate Chemical Properties,Usage,Production

Chemical Properties

Isopropyl chloroformate is a colorless liquid with corrosive properties and a pungent odor. generally present as 1.0 mol/L toluene solution of isopropyl chloroformate. It is a highly flammable chemical. Isopropyl chloroformate decomposes when heated, producing toxic and corrosive fumes, including hydrogen chloride and phosgene. The chemical reacts with water to produce alcohol and hydrogen chloride. Hydrolysis would yield chloroformic acid, which is considered a strong acid.

Uses

Chemical intermediate for free-radical polymerization initiators, organic synthesis.

Uses

Isopropyl chloroform was used in the preparation of isopropyl cyclohexane via alkylation of cyclohexene. It was also used in the preparation of 10-isopropyloctadecanoic acid via reaction with oleic acid in the presence of ethylaluminum sesquichloride

Production Methods

Prepared by the reaction of liquid anhydrous isopropyl alcohol with molar excess of dry, chlorine-free phosgene at low temperature.

General Description

A clear colorless volatile liquid with a pungent irritating odor. About the same density as water and insoluble in water. Floats on water Flash point 75°F. Very irritating to skin and eyes and very toxic by inhalation, ingestion and skin absorption. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Gives off HCl fumes in moist air. Insoluble in water. Decomposes slowly in water forming isopropyl alcohol, HCl, and CO2.

Reactivity Profile

Isopropyl chloroformate is water reactive. A sample stored in a refrigerator exploded [Wischmeyer 1973]. Attacks many metals especially in humid atmosphere [Handling Chemicals Safely, 1980. p. 476]. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Hazard

Toxic by inhalation.

Health Hazard

Acute: highly toxic by inhalation, ingestion and skin absorption. Delayed: can produce delayed pulmonary edema (2-24 hours after exposure) similar to that produced by phosgene. Inhalation of material may cause death or permanent injury.

Fire Hazard

Extremely dangerous; Isopropyl chloroformate has exploded while stored in refrigerator. Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Like other chlorides, when heated to decomposition or on contact with acids or acrid fumes, they evolve highly toxic chloride fumes. Reacts violently with phosgene. Unstable, avoid phosgene

Isopropyl chloroformate Preparation Products And Raw materials

Raw materials

Flow Cell

Preparation Products

Chlorpropham DIETHOFENCARB 3-FORMYL-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
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Isopropyl chloroformate Suppliers

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View Lastest Price from Isopropyl chloroformate manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
Isopropyl chloroformate 108-23-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 ton
Release date
2024-08-23
Career Henan Chemical Co
Product
Isopropyl chloroformate 108-23-6
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-15

108-23-6, Isopropyl chloroformateRelated Search:

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