Ketanserin

Product Name: Ketanserin
CAS No.: 74050-98-9
Chemical Name: Ketanserin
Synonyms: RHS;Ket;p73L;p73H;OFC8;EEC3;SHFM4;p53CP;TP53L;TP73L
CBNumber: CB5704758
Molecular Formula: C22H22FN3O3
Formula Weight: 395.43
MOL File: 74050-98-9.mol

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Ketanserin Property

Melting point:: 227-235°C
Density: 1.280±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: DMF: 10 mg/mL, clear, colorless
form: Solid
pka: 7.5(at 25℃)
color: White to Off-White
Merck: 14,5296
CAS DataBase Reference: 74050-98-9(CAS DataBase Reference)

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Safety

WGK Germany: 3
RTECS: VA1411190
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: K0051
Product name: Ketanserin
Purity: >98.0%(HPLC)(T)
Packaging: 200mg
Price: $62
Updated: 2024/03/01

TCI Chemical

Product number: K0051
Product name: Ketanserin
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $186
Updated: 2024/03/01

TRC

Product number: K165450
Product name: Ketanserin
Packaging: 250mg
Price: $135
Updated: 2021/12/16

TRC

Product number: K165450
Product name: Ketanserin
Packaging: 50mg
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-6055
Product name: Ketanserin
Purity: 98.57%
Packaging: 50mg
Price: $50
Updated: 2021/12/16

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Ketanserin Chemical Properties,Usage,Production

Description

Ketanserin is an antihypertensive agent with antagonist properties at both the serotonin-S2 and α1-adrenergic receptors. Its mechanism of action, while still controversial, may involve interactions at both of these loci.

Chemical Properties

Off-White Solid

Originator

Janssen (Belgium)

Uses

An antihypertensive, with affinity for multiple GPCR receptors.

Uses

receptor antagonist

Definition

ChEBI: A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.

brand name

SEREFREX

Purification Methods

It has been purified by recrystallisation from 4-methyl-3-pentanone [Peeters et al. Cryst Structure Commun 11 375 1982, Kacprowicz et al. J Chromatogr 272 417 1983, Davies et al. J Chromatogr 275 232 1983]. It is an antihypertensive.

Ketanserin Preparation Products And Raw materials

Raw materials

4-(4-Fluorobenzoyl)piperidine 2-Pentanone

Preparation Products

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Ketanserin Suppliers

Americas 1 Canada 2 China 171 Europe 4 Germany 2 India 6 Japan 1 Switzerland 1 The Netherlands 1 United Kingdom 8 United States 32 USA 1 Global 230

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View Lastest Price from Ketanserin manufacturers

Sinoway Industrial co., ltd.

Product: Ketanserin 74050-98-9
Price: US $0.00/Kg/Bag
Min. Order: 2Kg/Bag
Purity: 99% up / EP
Supply Ability: 20 tons
Release date: 2021-07-21

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Ketanserin 74050-98-9
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 99%min
Supply Ability: 10KG
Release date: 2021-06-08

Hebei Weibang Biotechnology Co., Ltd

Product: Ketanserin 74050-98-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-28

74050-98-9, KetanserinRelated Search:

Hydroxyurea Everolimus Vincristine sulfate RS-127445 ABT 737 A 769662 Barasertib (AZD1152-HQPA) Quinazoline Ketanserin/Ritanserin/Sufrexal/Serefrex KETANSERIN TARTRATE,KETANSERIN TARTRATE SALT,KETANSERIN TARTRATE (R 41468) (SELECTIVE 5-HT2/5-HT1C SEROTONI 7-azidoketanserin KETANSERIN HCL, [ETHYLENE-3H]-,KETANSERIN HYDROCHLORIDE, [ETHYLENE-3H]- Ketanserin 7-aminoketanserin

Ketanserin, 99%, a specific 5-HT2A serotonin receptor antagonist

B(p51A)

B(p51B)

EEC3

OFC8

p53CP

p63, GST tagged human

p73H

p73L

RHS

SHFM4

TP53CP

TP53L

TP73L

3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1h,3h]-quinazolinedione

KETANSERIN

3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)quinazoline-2,4(1H,3H)-dione

3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2，4-(IH，3H)-quinazolinedione

Ketanserin (Vulketan Gel)|

Ketanserin(R 41 468)

Ket

Ketensin

Perketan

R-49945

Serefrex

Serepress

Sufrexal

Taseron

2,4(1H,3H)-Quinazolinedione, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-

3-[2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl]-1H-quinazoline-2,4-dione

3-[2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl]-2,4(1H,3H)-quinazolinedione

3-[2-[4-(4-Fluorobenzoyl)piperidino]ethyl]-2,4(1H,3H)-quinazolinedione

Ketanserine

Ketanserin&gt

Ketanserinum

Ketanserin USP/EP/BP

Ketanserine Base

3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-1,2,3, 4-tetrahydroquinazoline-2,4-dione

TIANFU CHEM----Ketanserin

Ketanserin,3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione

3-[2-[4-(4-Fluorobenzoyl)-1-piperidyl]ethyl]quinazoline-2,4(1H,3H)-dione

74050-98-9

C22H22FN3O3

Intermediates & Fine Chemicals

Pharmaceuticals

Other APIs

ketone