ChemicalBook > CAS DataBase List > 2-HYDROXY-3-METHYLBUTYRIC ACID

2-HYDROXY-3-METHYLBUTYRIC ACID

Product Name
2-HYDROXY-3-METHYLBUTYRIC ACID
CAS No.
4026-18-0
Chemical Name
2-HYDROXY-3-METHYLBUTYRIC ACID
Synonyms
2-Hydroxy-3-methylbutanoic acid;2-HYDROXYISOVALERIC ACID;3-Methyl-2-hydroxybutyric Acid;Butanoic acid, 2-hydroxy-3-methyl-;Nsc 227884;AKOS 239-06;Einecs 223-697-5;2-HYDROXY-3-METHYLBU;2-Oxyisovaleric Acid;A-HYDROXYISOVALERIC ACID
CBNumber
CB5706262
Molecular Formula
C5H10O3
Formula Weight
118.13
MOL File
4026-18-0.mol
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2-HYDROXY-3-METHYLBUTYRIC ACID Property

Melting point:
86-87 °C (lit.)
Boiling point:
120-125 °C(Press: 17 Torr)
Density 
1.136±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in dimethyl sulfoxide and methanol.
form 
Solid
pka
3.87±0.16(Predicted)
color 
White
LogP
0.013 (est)
CAS DataBase Reference
4026-18-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
3-10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
219835
Product name
2-Hydroxy-3-methylbutyric acid
Purity
99%
Packaging
1g
Price
$201
Updated
2024/03/01
Alfa Aesar
Product number
H60872
Product name
2-Hydroxy-3-methylbutyric acid, 98%
Packaging
1g
Price
$67.5
Updated
2024/03/01
TRC
Product number
H946510
Product name
2-Hydroxy-3-methylbutyric acid
Packaging
5g
Price
$155
Updated
2021/12/16
TRC
Product number
H946510
Product name
2-Hydroxy-3-methylbutyric acid
Packaging
500mg
Price
$55
Updated
2021/12/16
TRC
Product number
H946510
Product name
2-Hydroxy-3-methylbutyric acid
Packaging
1g
Price
$65
Updated
2021/12/16
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2-HYDROXY-3-METHYLBUTYRIC ACID Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

2-Hydroxy-3-methylbutyric Acid is a α-hydroxylated butyric acid derivative used as a marker in chemical diagnosis of organic aciduria and other inborn errors. 2-Hydroxy-3-methylbutyric Acid is also us ed as a metabolomic biomarkers in preeclampsia.

Uses

2-Hydroxy-3-methylbutyric acid is employed as internal standard for analysis of ethylene glycol (EG) and γ-hydroxybutyrate (GHB) in whole blood.

Definition

ChEBI: A valine derivative that is valine in which the amino group has been replaced by a hydroxy group.

General Description

Chiral resolution of 2-hydroxy-3-methylbutyric acid without derivatization has been studied by capillary electrophoresis using 2-hydroxypropyl-β-cyclodextrin.

2-HYDROXY-3-METHYLBUTYRIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-HYDROXY-3-METHYLBUTYRIC ACID manufacturers

Career Henan Chemical Co
Product
(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID 4026-18-0
Price
US $20.00/KG
Min. Order
10KG
Purity
98%
Supply Ability
100kg
Release date
2018-08-02

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