ChemicalBook > CAS DataBase List > (S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID

(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID

Product Name
(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID
CAS No.
17407-55-5
Chemical Name
(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID
Synonyms
L-Valic acid;(S)-(+)-2-Hydroxy-3-;l-α-hydroxyisovaleric acid;L-2-Hydroxyisovaleric acid;L-a-Hydroxyisovaleric acid;(2S)-2-Hydroxyisovaleric acid;L-ALPHA-HYDROXYISOVALERIC ACID;2-HYDROXY-3-METHYLBUTYRIC ACID;3-METHYL-2-HYDROXY-BUTANOIC ACID;(S)-alpha-Hydroxyisovaleric acid
CBNumber
CB9275991
Molecular Formula
C5H10O3
Formula Weight
118.13
MOL File
17407-55-5.mol
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(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Property

Melting point:
68-70 °C (lit.)
Boiling point:
124-125 °C/13 mmHg (lit.)
Density 
1.136
refractive index 
1.4641 (estimate)
Flash point:
112℃
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form 
Powder
pka
3.87±0.16(Predicted)
color 
White
optical activity
[α]20/D +19°, c = 1 in chloroform
BRN 
1721140
InChI
1S/C5H10O3/c1-3(2)4(6)5(7)8/h3-4,6H,1-2H3,(H,7,8)/t4-/m0/s1
InChIKey
NGEWQZIDQIYUNV-BYPYZUCNSA-N
SMILES
CC(C)[C@H](O)C(O)=O
CAS DataBase Reference
17407-55-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
3-10
Hazard Note 
Irritant
HS Code 
29181990
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
379093
Product name
(S)-(+)-2-Hydroxy-3-methylbutyric acid
Purity
99%, optical purity ee: 99% (GLC)
Packaging
1g
Price
$98.6
Updated
2026/03/19
Sigma-Aldrich
Product number
379093
Product name
(S)-(+)-2-Hydroxy-3-methylbutyric acid
Purity
99%, optical purity ee: 99% (GLC)
Packaging
5g
Price
$250
Updated
2026/03/19
Cayman Chemical
Product number
10007090
Product name
(S)-(+)-2-hydroxy-3-Methylbutyric Acid
Purity
>98%
Packaging
500mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
10007090
Product name
(S)-(+)-2-hydroxy-3-Methylbutyric Acid
Purity
>98%
Packaging
1g
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
10007090
Product name
(S)-(+)-2-hydroxy-3-Methylbutyric Acid
Purity
>98%
Packaging
5g
Price
$199
Updated
2024/03/01
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(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Chemical Properties,Usage,Production

Chemical Properties

white fine crystalline powder

Uses

A useful chiral building block for peptide synthesis. Used in the preparation of the cytotoxic didemnin cyclopeptides and of the antineoplastic agent dolastatin 15.

Definition

ChEBI: (S)-2-hydroxy-3-methylbutyric acid is the S-enantiomer of 2-hydroxy-3-methylbutyric acid. It is used as a chiral building block for peptide synthesis. It has a role as a chiral reagent and a human metabolite. It is a conjugate acid of a (S)-2-hydroxy-3-methylbutyrate. It is an enantiomer of a (R)-2-hydroxy-3-methylbutyric acid.

(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Suppliers

ANHUI JINGKE BIOTECHNOLOGY CO.,LTD
Tel
15556523109
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sales@kingobiotech.com
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China
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J & K SCIENTIFIC LTD.
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18210857532; 18210857532
Fax
86-10-82849933
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jkinfo@jkchemical.com
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China
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96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006356688 18621169109
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86-21-61259102
Email
market03@meryer.com
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China
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40228
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Bridge Organics
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+1269-649-4200
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+1269-649-0611
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ab@bridgeorganics.com
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United States
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Energy Chemical
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021-021-58432009 400-005-6266
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021-58436166
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sales8178@energy-chemical.com
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China
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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0086-571-85864795
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China
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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info@hanhongsci.com
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China
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Chemsky (shanghai) International Co.,Ltd
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021-50135380
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shchemsky@sina.com
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China
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Syntechem Co.,Ltd
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Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
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Maya High Purity Chemicals
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+86 (573) 82222445 (0)18006601000 452520369
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+86 (573) 82222643
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sales@maya-r.com
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China
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View Lastest Price from (S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID manufacturers

Career Henan Chemical Co
Product
(S)-2-hydroxyvaleric acid 17407-55-5
Price
US $20.00/KG
Min. Order
10KG
Purity
99%
Supply Ability
100kg
Release date
2018-08-02

17407-55-5, (S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACIDRelated Search:


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  • (S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID
  • (S)-2-HYDROXY-3-METHYLBUTYRIC ACID
  • L-ALPHA-HYDROXYISOVALERIC ACID
  • 2S-HYDROXY-3-METHYL-BUTANOIC ACID
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  • (S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID, 99% (99% EE/GLC)
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  • (2R)-2-Hydroxy-3-methylbutanoic acid 97%
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  • (S)-3-Methyl-2-hydroxybutyric acid
  • (S)-(+)-2-Hydroxy-3-methylbutyric acid 99%, optical purity ee: 99% (GLC)
  • L-α-Hydroxyisovaleric acid,(S)-2-Hydroxy-3-methylbutyric acid
  • (S)-(+)-2-Hydroxy-3-methylbutyric acid,L-α-Hydroxyisovaleric acid
  • (S)-(+)-2-Hydroxy-3-
  • (2S)-(+)-2-Hydroxy-3-methylbutyric acid, L-alpha-Hydroxyisovaleric acid
  • (S)-alpha-Hydroxyisovaleric acid
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