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5-Cyanoindole

Product Name
5-Cyanoindole
CAS No.
15861-24-2
Chemical Name
5-Cyanoindole
Synonyms
1H-INDOLE-5-CARBONITRILE;indoline-5-carbonitrile;5-Cyanoindolecas;Indolecarbonitrile;INDOLE-5-CARBONITRILE;5-Cyanoindole, 99% 1GR;5-CI;5-CYANOINDOLE;5-Cyano-1H-indole;5-CYANOINDOLE 98%
CBNumber
CB5706833
Molecular Formula
C9H6N2
Formula Weight
142.16
MOL File
15861-24-2.mol
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5-Cyanoindole Property

Melting point:
106-108 °C(lit.)
Boiling point:
249.72°C (rough estimate)
Density 
1.1777 (rough estimate)
refractive index 
1.6211 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform, Hexane, Methanol
pka
15.62±0.30(Predicted)
form 
Crystalline Powder
color 
White to slightly yellow
Water Solubility 
Soluble in chloroform, hexane and methanol. Insoluble in water.
Sensitive 
Air & Light Sensitive
BRN 
116738
InChIKey
YHYLDEVWYOFIJK-UHFFFAOYSA-N
CAS DataBase Reference
15861-24-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-36-22
RIDADR 
3276
WGK Germany 
3
RTECS 
NL5993120
8-10
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
29339990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C92006
Product name
Indole-5-carbonitrile
Purity
99%
Packaging
5g
Price
$71.6
Updated
2024/03/01
Sigma-Aldrich
Product number
C92006
Product name
Indole-5-carbonitrile
Purity
99%
Packaging
10g
Price
$131
Updated
2023/06/20
TCI Chemical
Product number
C1491
Product name
5-Cyanoindole
Purity
>98.0%(GC)
Packaging
1g
Price
$27
Updated
2024/03/01
TCI Chemical
Product number
C1491
Product name
5-Cyanoindole
Purity
>98.0%(GC)
Packaging
5g
Price
$77
Updated
2024/03/01
Alfa Aesar
Product number
B21810
Product name
Indole-5-carbonitrile, 98+%
Packaging
1g
Price
$47.65
Updated
2024/03/01
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5-Cyanoindole Chemical Properties,Usage,Production

Chemical Properties

Off-White Crystalline Powder

Uses

• ;Reactant for parallel synthesis of dihydroisoquinolines via silver and L-proline co-catalyzed three-component coupling reaction1• ;Reactant for chemoselective and regioselective preparation of benzoyl indoles2• ;Reactant for preparation of novel PPARα/γ dual agonists for potential treatment of metabolic syndrome and IDDM3• ;Reactant for preparation of 4,5-dihydrocyclopenta[c]quinolines by palladium-catalyzed ring-expansion reaction alkynes, using O2 as the oxidant4• ;Reactant for preparation of vinylindoles by hydroarylation of alkynes using indium bromi

Uses

Inhibitor of enzyme.

Uses

Reactant used for parallel synthesis of dihydroisoquinolines via silver and L-proline co-catalyzed three-component coupling reaction, preparation of novel PPARα/γ dual agonists for potential treatment of metabolic syndrome and IDDM, chemo selective and regioselective preparation of benzoyl indoles, 4,5-dihydrocyclopenta[c]quinolines by palladium-catalyzed ring-expansion reaction alkynes, using O2 as the oxidant and vinylindoles by hydroarylation of alkynes using indium bromide catalyst.

Purification Methods

Dissolve the nitrile in 95% EtOH, boil it in the presence of charcoal, filter, evaporate to a small volume and add enough H2O to cause crystallisation and cool. Recrystallise it directly from aqueous EtOH and dry it in a vacuum. UV has at max 276 nm (log 3.6) in MeOH. [Lindwall & Mantell J Org Chem 18 345 1953, 20 1458 1955, Thesing at al. Chem Ber 95 2205 1962, NMR: Lallemend & Bernath Bull Soc Chim Fr 4091 1970, Beilstein 22/3 V 45.]

5-Cyanoindole Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Cyanoindole Suppliers

Ramidus AB
Tel
--
Fax
--
Email
info@ramidus.se
Country
Sweden
ProdList
155
Advantage
50
Ramidus AB
Tel
--
Fax
--
Email
hans.holmberg@synthelec.se
Country
Sweden
ProdList
1103
Advantage
30
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View Lastest Price from 5-Cyanoindole manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
5-Cyanoindole 15861-24-2
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-09
Hebei Best Biological Technology Co., Ltd
Product
5-Cyanoindole 15861-24-2
Price
US $200.00/g
Min. Order
10g
Purity
99%
Supply Ability
1000t/month
Release date
2022-11-14
Henan Aochuang Chemical Co.,Ltd.
Product
5-Cyanoindole 15861-24-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-19

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