ChemicalBook > CAS DataBase List > 2-Methylpropanedioic acid
2-Methylpropanedioic acid
- Product Name
- 2-Methylpropanedioic acid
- CAS No.
- 516-05-2
- Chemical Name
- 2-Methylpropanedioic acid
- Synonyms
- METHYLMALONIC ACID;2-Methylmalonic acid;AI315327;onic acid;NSC 25201;AI3 15327;AI3-15327;Methylmalonic;isosuccinicacid;Isosuccinic acid
- CBNumber
- CB5713714
- Molecular Formula
- C4H6O4
- Formula Weight
- 118.09
- MOL File
- 516-05-2.mol
More
Less
2-Methylpropanedioic acid Property
- Melting point:
- 128-130 °C (lit.)
- Boiling point:
- 272.71°C (rough estimate)
- Density
- 1.45
- refractive index
- 1.4304 (estimate)
- Flash point:
- 2℃
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Crystalline Powder
- pka
- 3.07, 5.76(at 25℃)
- color
- White
- Specific Gravity
- 1.455
- PH
- 3.23(1 mM solution);2.6(10 mM solution);2.05(100 mM solution)
- Water Solubility
- soluble
- BRN
- 1756084
- CAS DataBase Reference
- 516-05-2(CAS DataBase Reference)
- NIST Chemistry Reference
- Methylmalonic acid(516-05-2)
More
Less
Safety
- Hazard Codes
- Xi,Xn,F
- Risk Statements
- 36/37/38-36-20/21/22-11
- Safety Statements
- 26-36/37-16
- RIDADR
- UN 1648 3 / PGII
- WGK Germany
- 3
- RTECS
- OO1400000
- HS Code
- 29171900
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- M54058
- Product name
- Methylmalonic acid
- Purity
- 99%
- Packaging
- 5g
- Price
- $65.8
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- M-080
- Product name
- Methylmalonic acid solution
- Purity
- 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging
- 1mL
- Price
- $113
- Updated
- 2024/03/01
TCI Chemical
- Product number
- M0568
- Product name
- Methylmalonic Acid
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $74
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 14885
- Product name
- Methylmalonate
- Purity
- ≥95%
- Packaging
- 1g
- Price
- $20
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 14885
- Product name
- Methylmalonate
- Purity
- ≥95%
- Packaging
- 5g
- Price
- $48
- Updated
- 2024/03/01
More
Less
2-Methylpropanedioic acid Chemical Properties,Usage,Production
Chemical Properties
white crystalline powder
Uses
Methylmalonic acid can be used as a substrate in:
- Esterification reactions by various catalysts.
- Synthesis of pyrimidinium betaines with formamidine.
- Synthesis of malonic acid half thioester (MAHT).
Uses
2-Methylpropanedioic acid binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.
Definition
ChEBI: Methylmalonic acid is a dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group. It has a role as a human metabolite. It is functionally related to a malonic acid. It is a conjugate acid of a methylmalonate(1-).
Biological Functions
Methylmalonic acid is capable of diffusing out of cells in which it is being produced, so it may be detected in excess in the blood, CSF, and urine of patients with these various forms of the disease.
General Description
Methylmalonic acid is an indicator of vitamin B12 deficiency and methylmalonic acidemia. This Certified Spiking Solution? is suitable for use in preparation of calibrators or controls in clinical and diagnostic testing using GC/MS or LC/MS.
storage
Store at RT
Purification Methods
The acid crystallises as the hydrate from water. [Beilstein 2 IV 1932.]
2-Methylpropanedioic acid Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
2-Methylpropanedioic acid Suppliers
- Tel
- 027-65526929 15102793023
- Fax
- 027-65526669
- hbhxry@foxmail.com
- Country
- China
- ProdList
- 2006
- Advantage
- 55
- Tel
- 0592-7828678 18050056030
- Fax
- 0592-7828678
- 357187337@qq.com
- Country
- China
- ProdList
- 59
- Advantage
- 58
- Tel
- 0573-82813639 15157377625
- Fax
- 0573-82813637
- sales@jlightchem.com
- Country
- China
- ProdList
- 167
- Advantage
- 58
- Tel
- 010-57903446 15869909019
- Fax
- 010-57903446
- 168931144@qq.com
- Country
- China
- ProdList
- 2994
- Advantage
- 58
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 94657
- Advantage
- 76
- Tel
- 021-61259108 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 010-88425576
- Fax
- (+86)-10-88425546
- sales@dhltchem.com
- Country
- China
- ProdList
- 793
- Advantage
- 59
- Tel
- +86 351 7031519
- Fax
- +86 351 7031519
- sales@RHFChem.com
- Country
- China
- ProdList
- 2338
- Advantage
- 56
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 010-60275820 13031183356
- Fax
- 010-60270825
- elainezt@sina.com
- Country
- China
- ProdList
- 1390
- Advantage
- 62
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44689
- Advantage
- 61
- Tel
- 010-82967028 13552068683
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12386
- Advantage
- 60
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11655
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42958
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18738
- Advantage
- 57
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
- Tel
- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14435
- Advantage
- 57
- Tel
- Please Send Email 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 4378
- Advantage
- 65
- Tel
- +86 (573) 82222445 (0)18006601000 452520369
- Fax
- +86 (573) 82222643
- sales@maya-r.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 021-021-021-67601398-809-809-809 15221380277
- Fax
- 021-57711696
- marketing_china@spectrumchemical.com
- Country
- China
- ProdList
- 9658
- Advantage
- 60
- Tel
- 86-21-34053660
- Fax
- 86-21-34053661
- sale@labgogo.com
- Country
- China
- ProdList
- 9865
- Advantage
- 52
- Tel
- 800-810-5118
- Fax
- +86-10-84193589
- cnchemical@thermofisher.com
- Country
- China
- ProdList
- 17770
- Advantage
- 75
- Tel
- 400-810-7969 010-59572699
- Fax
- 010-59572688
- ningzi.li@inno-chem.com.cn
- Country
- China
- ProdList
- 6134
- Advantage
- 55
- Tel
- 025-66099280 17798518460
- Fax
- (1)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 19915
- Advantage
- 55
- Tel
- 18017383231 18017383231
- Fax
- qq：2817624287
- lyh_antaeus@163.com
- Country
- China
- ProdList
- 9347
- Advantage
- 55
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 18209
- Advantage
- 56
- Tel
- 400-6206333 18021050169
- Fax
- 021-50323701
- market@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- 021-021-33632979 15002134094
- Fax
- 021-33632979
- marketing@targetmol.com
- Country
- China
- ProdList
- 7783
- Advantage
- 58
- Tel
- 021-33632979
- Fax
- 021-34692979
- info@tsbiochem.com
- Country
- China
- ProdList
- 8065
- Advantage
- 58
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 41462
- Advantage
- 60
- Tel
- 021-54359730 400-008-9730
- Fax
- 021-54353864
- info@chemxyz.com
- Country
- China
- ProdList
- 3991
- Advantage
- 60
- Tel
- 0371-13526885213 15637198702
- Fax
- 0371-63709726
- xpkchem@163.com
- Country
- China
- ProdList
- 3980
- Advantage
- 58
- Tel
- 023-89130144 18523560356
- Fax
- 023-67534737
- zhyong1011@163.com
- Country
- China
- ProdList
- 297
- Advantage
- 58
- Tel
- 021-021-56795766
- Fax
- +86-21-56795266
- sales@worldyachem.com
- Country
- China
- ProdList
- 9349
- Advantage
- 58
- Tel
- 400-1166-196 13458535857
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 13350
- Advantage
- 58
- Tel
- 0512-87182056 18013166090
- Fax
- 0512-87182056
- lingling.qi@yacoo.com.cn
- Country
- China
- ProdList
- 7295
- Advantage
- 60
- Tel
- 400-821-5857 021-64326257
- Fax
- 021-64393586 QQ;2798200800
- credit-chem@foxmail.com
- Country
- China
- ProdList
- 5219
- Advantage
- 58
- Tel
- 027-59262863 13277907145 3091977954
- Fax
- 027-59420980
- Country
- China
- ProdList
- 4943
- Advantage
- 58
- Tel
- 15221275939 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 16166
- Advantage
- 55
- Tel
- 021-69106960 13701823733
- Fax
- 021-69106780
- 13701823733@163.com
- Country
- China
- ProdList
- 4772
- Advantage
- 60
- Tel
- 0373-7129549; 13598610367
- Fax
- QQ:2468833170
- 2841375912@qq.com
- Country
- China
- ProdList
- 2727
- Advantage
- 52
- Tel
- 13718199399
- Fax
- QQ : 206661479
- holiyangchem@163.com
- Country
- China
- ProdList
- 3381
- Advantage
- 56
- Tel
- 021-69005955 13701776567
- Fax
- 021-69005775
- youpengchem@163.com
- Country
- China
- ProdList
- 4295
- Advantage
- 56
- Tel
- 13708085536
- Fax
- QQ : 121102042
- hanovichem@163.com
- Country
- China
- ProdList
- 3383
- Advantage
- 56
- Tel
- 021-021-69182866 13701855675
- Fax
- 021-69182022
- tongyuanchem@126.com
- Country
- China
- ProdList
- 4321
- Advantage
- 58
- Tel
- 021-33516722 13701817765
- Fax
- 021-33516776
- kaisaichem@163.com
- Country
- China
- ProdList
- 4743
- Advantage
- 58
- Tel
- 021-69515658 ; 69515628 13701998368
- Fax
- 021-69515998
- longrunchem@163.com
- Country
- China
- ProdList
- 3912
- Advantage
- 50
- Tel
- 021-69992220 13701886816
- Fax
- 021-69992237
- roleadchem@163.com
- Country
- China
- ProdList
- 4750
- Advantage
- 50
More
Less
View Lastest Price from 2-Methylpropanedioic acid manufacturers
Hubei Yiling biotechnology Co Ltd
- Product
- 2-Methylpropanedioic acid 516-05-2
- Price
- US $0.00/G/KG
- Min. Order
- 1G/KG
- Purity
- 99%
- Supply Ability
- 100MT
- Release date
- 2025-02-14
Hebei Mujin Biotechnology Co.,Ltd
- Product
- 2-Methylpropanedioic acid 516-05-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-08-24
Hebei Weibang Biotechnology Co., Ltd
- Product
- 2-Methylpropanedioic acid 516-05-2
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-15
516-05-2, 2-Methylpropanedioic acidRelated Search:
Diethyl methylmalonate
2,4-Difluoronitrobenzene
flurbiprofen
4-Acetyl-2-fluorobiphenyl
Flurbiprofen Impurity 8
Flurbiprofen Impurity 15
2,4-Difluorobiphenyl
diethyl (3-fluoro-4-nitrophenyl)methylmalonate
4'-hydroxyflurbiprofen
2-Fluorobiphenyl-4-carboxylic Acid
Flurbiprofen Impurity
Flurbiprofen Related Impurity 1
4-ETHYL-2-FLUORO-1,1'-BIPHENYL
diethyl (4-amino-3-fluorophenyl)methylmalonate
Flurbiprofen Impurity 16
(2-FLUORO-4-BIPHENYL)ACETIC ACID
α-Hydroxy Flurbiprofen
3-Fluoro-4-phenylphenol
Methylmalonic Acid