2-Methylpropanedioic acid
- Product Name
- 2-Methylpropanedioic acid
- CAS No.
- 516-05-2
- Chemical Name
- 2-Methylpropanedioic acid
- Synonyms
- METHYLMALONIC ACID;2-Methylmalonic acid;AI315327;onic acid;NSC 25201;AI3 15327;AI3-15327;Methylmalonic;isosuccinicacid;Isosuccinic acid
- CBNumber
- CB5713714
- Molecular Formula
- C4H6O4
- Formula Weight
- 118.09
- MOL File
- 516-05-2.mol
2-Methylpropanedioic acid Property
- Melting point:
- 128-130 °C (lit.)
- Boiling point:
- 272.71°C (rough estimate)
- Density
- 1.45
- refractive index
- 1.4304 (estimate)
- Flash point:
- 2℃
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Crystalline Powder
- pka
- 3.07, 5.76(at 25℃)
- color
- White
- Specific Gravity
- 1.455
- PH
- 3.23(1 mM solution);2.6(10 mM solution);2.05(100 mM solution)
- Water Solubility
- soluble
- BRN
- 1756084
- CAS DataBase Reference
- 516-05-2(CAS DataBase Reference)
- NIST Chemistry Reference
- Methylmalonic acid(516-05-2)
Safety
- Hazard Codes
- Xi,Xn,F
- Risk Statements
- 36/37/38-36-20/21/22-11
- Safety Statements
- 26-36/37-16
- RIDADR
- UN 1648 3 / PGII
- WGK Germany
- 3
- RTECS
- OO1400000
- HS Code
- 29171900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M54058
- Product name
- Methylmalonic acid
- Purity
- 99%
- Packaging
- 5g
- Price
- $65.8
- Updated
- 2024/03/01
- Product number
- M-080
- Product name
- Methylmalonic acid solution
- Purity
- 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging
- 1mL
- Price
- $113
- Updated
- 2024/03/01
- Product number
- M0568
- Product name
- Methylmalonic Acid
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $74
- Updated
- 2024/03/01
- Product number
- 14885
- Product name
- Methylmalonate
- Purity
- ≥95%
- Packaging
- 1g
- Price
- $20
- Updated
- 2024/03/01
- Product number
- 14885
- Product name
- Methylmalonate
- Purity
- ≥95%
- Packaging
- 5g
- Price
- $48
- Updated
- 2024/03/01
2-Methylpropanedioic acid Chemical Properties,Usage,Production
Chemical Properties
white crystalline powder
Uses
Methylmalonic acid can be used as a substrate in:
- Esterification reactions by various catalysts.
- Synthesis of pyrimidinium betaines with formamidine.
- Synthesis of malonic acid half thioester (MAHT).
Uses
2-Methylpropanedioic acid binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.
Definition
ChEBI: Methylmalonic acid is a dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group. It has a role as a human metabolite. It is functionally related to a malonic acid. It is a conjugate acid of a methylmalonate(1-).
Biological Functions
Methylmalonic acid is capable of diffusing out of cells in which it is being produced, so it may be detected in excess in the blood, CSF, and urine of patients with these various forms of the disease.
General Description
Methylmalonic acid is an indicator of vitamin B12 deficiency and methylmalonic acidemia. This Certified Spiking Solution? is suitable for use in preparation of calibrators or controls in clinical and diagnostic testing using GC/MS or LC/MS.
storage
Store at RT
Purification Methods
The acid crystallises as the hydrate from water. [Beilstein 2 IV 1932.]
2-Methylpropanedioic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-Methylpropanedioic acid Suppliers
- Tel
- --
- Fax
- --
- chiron@chiron.no
- Country
- Norway
- ProdList
- 2801
- Advantage
- 72
View Lastest Price from 2-Methylpropanedioic acid manufacturers
- Product
- 2-Methylpropanedioic acid 516-05-2
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-15
- Product
- 2-Methylpropanedioic acid 516-05-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 5KG
- Purity
- 99%
- Supply Ability
- 1000 kg/Month
- Release date
- 2024-05-15
- Product
- 2-Methylpropanedioic acid 516-05-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-08-24