ChemicalBook > CAS DataBase List > 2-Quinolinol

2-Quinolinol

Product Name
2-Quinolinol
CAS No.
59-31-4
Chemical Name
2-Quinolinol
Synonyms
2-HYDROXYQUINOLINE;2(1h)-quinolinone;2-QUINOLONE;CARBOSTYRIL;2-quinolinone;1,2-Dihydroquinolin-2-one;2-Quinoline;2-QUINOLINOL;2-Quinolinol 50;2(1H)-Quinolone
CBNumber
CB5730153
Molecular Formula
C9H7NO
Formula Weight
145.16
MOL File
59-31-4.mol
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2-Quinolinol Property

Melting point:
198-199 °C (lit.)
Boiling point:
264.27°C (rough estimate)
Density 
1.1555 (rough estimate)
refractive index 
1.4500 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
alcohol: soluble(lit.)
form 
Powder
pka
-0.31, 11.76(at 20℃)
color 
White to light purple or purple-brownish
Water Solubility 
1.052g/L(20 ºC)
Merck 
14,1825
BRN 
2855
CAS DataBase Reference
59-31-4(CAS DataBase Reference)
NIST Chemistry Reference
2(1H)-Quinolinone(59-31-4)
EPA Substance Registry System
2(1H)-Quinolinone (59-31-4)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-20/21/22-41-37/38-22
Safety Statements 
26-37/39-36
RIDADR 
2811
WGK Germany 
3
RTECS 
FG7175000
Hazard Note 
Harmful/Irritant
TSCA 
Yes
HS Code 
29334900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
270873
Product name
2-Hydroxyquinoline
Purity
98%
Packaging
1g
Price
$59.2
Updated
2024/03/01
Sigma-Aldrich
Product number
270873
Product name
2-Hydroxyquinoline
Purity
98%
Packaging
5g
Price
$125
Updated
2024/03/01
TCI Chemical
Product number
H0304
Product name
2-Quinolinol
Purity
>98.0%(GC)
Packaging
1g
Price
$19
Updated
2024/03/01
TCI Chemical
Product number
H0304
Product name
2-Quinolinol
Purity
>98.0%(GC)
Packaging
10g
Price
$108
Updated
2024/03/01
TRC
Product number
H954215
Product name
2-Hydroxyquinoline
Packaging
500mg
Price
$75
Updated
2021/12/16
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2-Quinolinol Chemical Properties,Usage,Production

Chemical Properties

white to light purple or purple-brownish powder

Uses

2-Hydroxyquinoline was used to obtain the design of the platinum(IV) complexes with intense bands shifted towards longer wavelengths. The Pt(IV) complexes are inert stable prodrugs that were photoactivated to produce Pt(II) species with promising anticancer activity.

Definition

ChEBI: A quinolone that is 1,2-dihydroquinoline substituted by an oxo group at position 2.

Synthesis Reference(s)

Synthesis, p. 739, 1975 DOI: 10.1055/s-1975-23918

General Description

2-Hydroxyquinoline is a specific inhibitor of plaque paraoxonase1 (PON1).

Purification Methods

Crystallise it from MeOH. It has m 200-201o after sublimation in a vacuum. The picrate has m 132o after crystallisation from Et2O. [Gibson et al. J Chem Soc 4340 1955, Beilstein 21 III/IV 1057, 21/8 V 217.]

2-Quinolinol Preparation Products And Raw materials

Raw materials

Quinoline Ethanol Acetic anhydride Hydrogen peroxide Tosyl chloride Acetic acid

Preparation Products

RUFLOXACIN 2-CHLOROQUINOLIN-6-AMINE 4-hydroxy-1-methyl-3-[(3-nitrophenyl)azo]-2-quinolone 2-Chloroquinoline Rebamipide Dibucaine hydrochloride
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2-Quinolinol Suppliers

Americas 1 Austria 1 Belgium 1 China 219 Europe 3 France 2 Germany 5 India 12 Japan 3 Slovakia 1 South Korea 2 Switzerland 2 United Kingdom 9 United States 43 Global 304
Hebei Fanbo Pharmaceutical Technology Co., Ltd.
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View Lastest Price from 2-Quinolinol manufacturers

Hebei Zhanyao Biotechnology Co. Ltd
Product
2-Quinolinol 59-31-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-10-14
Dideu Industries Group Limited
Product
2-Quinolinol 59-31-4
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-18
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Quinolinol 59-31-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

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